Agglutination meaning

Andrea Taktak Mrs. Taktak is in her 21st year of teaching high school science courses. She has designed curriculum and lessons for Forensic Science and Sports Medicine, and has taught Honors Biology, Anatomy and Physiology, Physical Science, and Environmental Science. Mrs. Taktak is a Master Teacher with a Teacher Leader Endorsement and has a Masters Degree in Education from Graceland University as well as a Bachelors of Science degree from Northern Kentucky University. She also most recently earned her Ohio Certified Volunteer Naturalist certificate while studying and volunteering at the Cincinnati Nature Center. • Instructor The body's immune system does a fabulous job of picking up on cells or toxins that are not supposed to be present. Part of the immune response uses agglutinin to rid the body of unwanted cells, such as pathogenic bacteria, viruses, fungi, or other invaders in a process called agglutination. What is agglutinin? Agglutinin is a special kind of antibody that binds foreign cells together, forming a clump. The process of forming the clump is called agglutination. Other antibodies then bind to the clumped foreign matter in the blood and mark it for destruction. Function and Working of Agglutinin Agglutination is the part of an immune response that tags or marks the grouped cells and makes them an easy target. For agglutination to occur, the body must discover a pathogen or foreign material. An agglutinin (a special antibody) will specifically bind to the o...

Agglutination Definition • Agglutination reactions are used to particulate test antigens that are usually conjugated to a carrier. • The carrier can either be artificial (such as latex or charcoal particles) or biological (such as red blood cells). • The agglutination process involving red blood cells is termed hemagglutination, and the process with white blood cells is termed leukoagglutination. • These conjugated particles then react with the patient’s serum which might or might not contain antibodies. • The result of this test can be collected based on the observation of clumps resulting from that antigen-antibody complex formation. • The sensitivity and accuracy of the result depend on a number of factors like the duration of incubation with the antibody, amount and strength of the antigen conjugated to the carrier, and test conditions like the pH and protein concentration. • Different forms of agglutination are used in diagnostic tests which include latex agglutination, flocculation tests, direct bacterial agglutination, and hemagglutination. • Because the process is quick and straightforward, these diagnostic tests are preferred over other sophisticated tests. • Agglutination has been used for the detection of antigens in bacteria which ultimately helps in the identification of those bacteria. • A modified and more sensitive technique associated with agglutination is agglutination-PCR. • In this technique, the antibodies bind and agglutinate with antigen-DNA conjug...

Introduction of Widal Test • Widal Test is an agglutination test which detects the presence of serum agglutinins (H and O) in patients serum with typhoid and paratyphoid fever. • When facilities for culturing are not available, the Widal test is the reliable and can be of value in the diagnosis of typhoid fevers in endemic areas. • It was developed byGeorges Ferdinand Widal in 1896. • The patient’s serum is tested for O andH antibodies (agglutinins) against the following antigen suspensions(usually stained suspensions): S. Typhi 0 antigen suspension, 9, 12 S. Typhi H antigen suspension, d S. Paratyphi A 0 antigen suspension, 1, 2, 12 S. Paratyphi A H antigen suspension, a S. Paratyphi B 0 antigen suspension, 1, 4, 5, 12 S. Paratyphi B H antigen suspension, b, phase 1 S. Paratyphi C 0 antigen suspension, 6, 7 S. Paratyphi C H antigen suspension, c, phase 1 • Salmonella antibody starts appearing in serum at the end of first week and rise sharply during the 3rd week of endemic fever.In acute typhoid fever, Oagglutinins can usually be detected 6–8 days afterthe onset of fever and H agglutinins after 10–12days. • It is preferable to test two specimens of sera at an interval of 7 to 10 days to demonstrate a rising antibody titre. • Salmonella antigen suspensions can be used as slide and tubetechniques. Principle of Widal Test Bacterial suspension which carry antigen will agglutinate on exposure to antibodies to Salmonella organisms. Patients’ suffering from enteric fever would p...

from The American Heritage® Dictionary of the English Language, 5th Edition. • noun The act or process of agglutinating; adhesion of distinct parts. • noun A clumped mass of material formed by agglutination. • noun Physiology The clumping together of red blood cells or bacteria, usually in response to a particular antibody. • noun Linguistics The formation of words from morphemes that retain their original forms and meanings with little change during the combination process. from The Century Dictionary. • noun In Wundt's psychology, the simplest type of apperceptive connection of ideas: a connection in which one is still clearly conscious of the constituent ideas, while the total idea aroused by their conjunction is nevertheless unitary: for example, watch-tower, steamboat. • noun In bacteriology, the clumping or coalescence of red blood-corpuscles or bacteria brought about by the action of special agglutinating substances (agglutinins). • noun The act of uniting by glue or other tenacious substance; the state of being thus united; adhesion of parts; that which is united; a mass or group cemented together. • noun In philology, the condition of being agglutinate; the process or result of agglutinate combination. See agglutinate, a. from the GNU version of the Collaborative International Dictionary of English. • noun The act of uniting by glue or other tenacious substance; the state of being thus united; adhesion of parts. • noun (Physiol.) Combination in which root words ar...

Agglutination Definition • Agglutination reactions are used to particulate test antigens that are usually conjugated to a carrier. • The carrier can either be artificial (such as latex or charcoal particles) or biological (such as red blood cells). • The agglutination process involving red blood cells is termed hemagglutination, and the process with white blood cells is termed leukoagglutination. • These conjugated particles then react with the patient’s serum which might or might not contain antibodies. • The result of this test can be collected based on the observation of clumps resulting from that antigen-antibody complex formation. • The sensitivity and accuracy of the result depend on a number of factors like the duration of incubation with the antibody, amount and strength of the antigen conjugated to the carrier, and test conditions like the pH and protein concentration. • Different forms of agglutination are used in diagnostic tests which include latex agglutination, flocculation tests, direct bacterial agglutination, and hemagglutination. • Because the process is quick and straightforward, these diagnostic tests are preferred over other sophisticated tests. • Agglutination has been used for the detection of antigens in bacteria which ultimately helps in the identification of those bacteria. • A modified and more sensitive technique associated with agglutination is agglutination-PCR. • In this technique, the antibodies bind and agglutinate with antigen-DNA conjug...

Andrea Taktak Mrs. Taktak is in her 21st year of teaching high school science courses. She has designed curriculum and lessons for Forensic Science and Sports Medicine, and has taught Honors Biology, Anatomy and Physiology, Physical Science, and Environmental Science. Mrs. Taktak is a Master Teacher with a Teacher Leader Endorsement and has a Masters Degree in Education from Graceland University as well as a Bachelors of Science degree from Northern Kentucky University. She also most recently earned her Ohio Certified Volunteer Naturalist certificate while studying and volunteering at the Cincinnati Nature Center. • Instructor The body's immune system does a fabulous job of picking up on cells or toxins that are not supposed to be present. Part of the immune response uses agglutinin to rid the body of unwanted cells, such as pathogenic bacteria, viruses, fungi, or other invaders in a process called agglutination. What is agglutinin? Agglutinin is a special kind of antibody that binds foreign cells together, forming a clump. The process of forming the clump is called agglutination. Other antibodies then bind to the clumped foreign matter in the blood and mark it for destruction. Function and Working of Agglutinin Agglutination is the part of an immune response that tags or marks the grouped cells and makes them an easy target. For agglutination to occur, the body must discover a pathogen or foreign material. An agglutinin (a special antibody) will specifically bind to the o...

from The American Heritage® Dictionary of the English Language, 5th Edition. • noun The act or process of agglutinating; adhesion of distinct parts. • noun A clumped mass of material formed by agglutination. • noun Physiology The clumping together of red blood cells or bacteria, usually in response to a particular antibody. • noun Linguistics The formation of words from morphemes that retain their original forms and meanings with little change during the combination process. from The Century Dictionary. • noun In Wundt's psychology, the simplest type of apperceptive connection of ideas: a connection in which one is still clearly conscious of the constituent ideas, while the total idea aroused by their conjunction is nevertheless unitary: for example, watch-tower, steamboat. • noun In bacteriology, the clumping or coalescence of red blood-corpuscles or bacteria brought about by the action of special agglutinating substances (agglutinins). • noun The act of uniting by glue or other tenacious substance; the state of being thus united; adhesion of parts; that which is united; a mass or group cemented together. • noun In philology, the condition of being agglutinate; the process or result of agglutinate combination. See agglutinate, a. from the GNU version of the Collaborative International Dictionary of English. • noun The act of uniting by glue or other tenacious substance; the state of being thus united; adhesion of parts. • noun (Physiol.) Combination in which root words ar...

Introduction of Widal Test • Widal Test is an agglutination test which detects the presence of serum agglutinins (H and O) in patients serum with typhoid and paratyphoid fever. • When facilities for culturing are not available, the Widal test is the reliable and can be of value in the diagnosis of typhoid fevers in endemic areas. • It was developed byGeorges Ferdinand Widal in 1896. • The patient’s serum is tested for O andH antibodies (agglutinins) against the following antigen suspensions(usually stained suspensions): S. Typhi 0 antigen suspension, 9, 12 S. Typhi H antigen suspension, d S. Paratyphi A 0 antigen suspension, 1, 2, 12 S. Paratyphi A H antigen suspension, a S. Paratyphi B 0 antigen suspension, 1, 4, 5, 12 S. Paratyphi B H antigen suspension, b, phase 1 S. Paratyphi C 0 antigen suspension, 6, 7 S. Paratyphi C H antigen suspension, c, phase 1 • Salmonella antibody starts appearing in serum at the end of first week and rise sharply during the 3rd week of endemic fever.In acute typhoid fever, Oagglutinins can usually be detected 6–8 days afterthe onset of fever and H agglutinins after 10–12days. • It is preferable to test two specimens of sera at an interval of 7 to 10 days to demonstrate a rising antibody titre. • Salmonella antigen suspensions can be used as slide and tubetechniques. Principle of Widal Test Bacterial suspension which carry antigen will agglutinate on exposure to antibodies to Salmonella organisms. Patients’ suffering from enteric fever would p...

Agglutination Definition • Agglutination reactions are used to particulate test antigens that are usually conjugated to a carrier. • The carrier can either be artificial (such as latex or charcoal particles) or biological (such as red blood cells). • The agglutination process involving red blood cells is termed hemagglutination, and the process with white blood cells is termed leukoagglutination. • These conjugated particles then react with the patient’s serum which might or might not contain antibodies. • The result of this test can be collected based on the observation of clumps resulting from that antigen-antibody complex formation. • The sensitivity and accuracy of the result depend on a number of factors like the duration of incubation with the antibody, amount and strength of the antigen conjugated to the carrier, and test conditions like the pH and protein concentration. • Different forms of agglutination are used in diagnostic tests which include latex agglutination, flocculation tests, direct bacterial agglutination, and hemagglutination. • Because the process is quick and straightforward, these diagnostic tests are preferred over other sophisticated tests. • Agglutination has been used for the detection of antigens in bacteria which ultimately helps in the identification of those bacteria. • A modified and more sensitive technique associated with agglutination is agglutination-PCR. • In this technique, the antibodies bind and agglutinate with antigen-DNA conjug...

Andrea Taktak Mrs. Taktak is in her 21st year of teaching high school science courses. She has designed curriculum and lessons for Forensic Science and Sports Medicine, and has taught Honors Biology, Anatomy and Physiology, Physical Science, and Environmental Science. Mrs. Taktak is a Master Teacher with a Teacher Leader Endorsement and has a Masters Degree in Education from Graceland University as well as a Bachelors of Science degree from Northern Kentucky University. She also most recently earned her Ohio Certified Volunteer Naturalist certificate while studying and volunteering at the Cincinnati Nature Center. • Instructor The body's immune system does a fabulous job of picking up on cells or toxins that are not supposed to be present. Part of the immune response uses agglutinin to rid the body of unwanted cells, such as pathogenic bacteria, viruses, fungi, or other invaders in a process called agglutination. What is agglutinin? Agglutinin is a special kind of antibody that binds foreign cells together, forming a clump. The process of forming the clump is called agglutination. Other antibodies then bind to the clumped foreign matter in the blood and mark it for destruction. Function and Working of Agglutinin Agglutination is the part of an immune response that tags or marks the grouped cells and makes them an easy target. For agglutination to occur, the body must discover a pathogen or foreign material. An agglutinin (a special antibody) will specifically bind to the o...