Anisole formula

Anisole is widely used as a solvent for the synthesis of various organic compounds, anethole, nonylphenol isomer 4-(3',6'-dimethyl-3-heptyl)phenol, perfumes, insect pheromones and pharmaceuticals. It finds application in the preparation of inorganic complexes and materials such as tin-core/tin oxide nanoparticles. Literature References The rate of ortho-lithiation of anisole is accelerated dramatically in the presence of TMEDA, effective also in sub-stoichiometric amounts: Tetrahedron Lett., 35, 385 (1994). For discussion of the mechanism of ortho-lithiation, see: J. Org. Chem., 62, 3024 (1997). Although direct dilithiation with n-BuLi/TMEDA was unsuccessful, a sequence involving monolithiation, silylation and further lithiation at the 6-position gave the 2,6-disilyl derivative in 72% yield: J. Org. Chem., 49, 4657 (1984). Widely used as a carbocation scavenger in the deblocking of, e.g. N-Boc or N-Cbz (Z) peptides with acidic reagents. Addition of anisole removes t-butyl or benzyl cations from the reaction mixture; see, e.g.: J. Chem. Soc., Chem. Commun., 922 (1976); Chem. Pharm. Bull., 25, 2929 (1977); Chem. Ber., 101, 3649 (1968). Lee, W-S.; Kumar, A.; Wang, Z.; Bhan, A. Chemical Titration and Transient Kinetic Studies of Site Requirements in Mo2C-Catalyzed Vapor Phase Anisole Hydrodeoxygenation. ACS Cata. 2015, 5 (7), 4104-4114. Peters, J. E.; Carpenter, J. R.; David, D. C. Anisole and Guaiacol Hydrodeoxygenation Reaction Pathways over Selected Catalysts. Energy Fuels ...

Cas No. 100-66-3 SDF PubChem ID 7519 Appearance Powder Formula C7H8O M.Wt 108.13 Type of Compound Phenols Storage Desiccate at -20°C Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. Chemical Name anisole SMILES COC1=CC=CC=C1 Standard InChIKey RDOXTESZEPMUJZ-UHFFFAOYSA-N General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. Structure Identificat...

• Spadone, Jean Claude; Jean Claude Spadone; Gary Takeoka; Remy Liardon (1990). "Analytical investigation of Rio off-flavor in green coffee". Journal of Agricultural and Food Chemistry. 38: 226–233. • Takeuchi, Hiroko; Hiroyuki Kato; Takashi Kurahashi (2013-09-16). Proceedings of the National Academy of Sciences. 110 (40): 16235–40.

• • • $100.00 / 1Kg/Drum • 2023-06-15 • CAS:100-66-3 • Min. Order: 1Kg/Drum • Purity: 99% • Supply Ability: 1000kg/month • • • $150.00 / 1ASSAYS • 2023-06-02 • CAS:100-66-3 • Min. Order: 10g • Purity: >99% • Supply Ability: 500kg/month • • • $10.00 / 25kg • 2023-05-27 • CAS:100-66-3 • Min. Order: 25kg • Purity: 99% • Supply Ability: 500t/month Anisole Chemical Properties Melting point -37 °C (lit.) Boiling point 154 °C (lit.) density 0.995 g/mL at 25 °C (lit.) vapor density 3.7 (vs air) vapor pressure 10 mm Hg ( 42.2 °C) FEMA refractive index n 20/D 1.516(lit.) Fp 125°F storage temp. Store below +30°C. solubility 1.71g/l form Liquid color Clear colorless Relative polarity 0.198 Odor phenol, anise odor Odor Threshold 0.057ppm explosive limit 0.34-6.3%(V) Odor Type phenolic Water Solubility 1.6 g/L (20 ºC) Merck 14,669 JECFA Number 1241 BRN 506892 Stability: Stable. Flammable. Incompatible with strong oxidizing agents. InChIKey RDOXTESZEPMUJZ-UHFFFAOYSA-N LogP 2.62 at 30℃ CAS DataBase Reference NIST Chemistry Reference EPA Substance Registry System Anisole Usage And Synthesis Anisole, also known as anise ether, methoxybenzene methyl phenyl ether, is a colorless liquid with an odor of anise, sweet, naturally present in the tarragon oil, insoluble in water, soluble in alcohol, ether, acetone, soluble in benzene. It irritates the eyes and mucous membranes. It is obtained originally from distilled methyl salicylate or methoxybenzoate, is now mainly produced through the reaction ...

If 40 is presented with an electrophile like acrolein or methyl vinyl ketone, then cations 42a and 42b are obtained. Harman and his co-workers then found that 42a could react with an enolate ion to produce the tungsten complex 43. In another route, nucleophilic attack on the carbonyl groups in 42a-b triggered an intramolecular Michael addition, producing the oxahydrodecalin ligands 44a-d, 45 and 46. Even more elaborate reactions were used to prepare the novel, bicyclic ligand shown in 47. 18 Anisole is a reactive aromatic substrate and undergoes Friedel–Crafts acylations under a diverse range of conditions to give p-ketone ( 7) (the o-isomer is sometimes observed, e.g., ). Besides the standard reactions with carboxylic acids, acid chlorides, or anhydrides and a strong Lewis acid, many less active catalysts (e.g., AgClO 4, TiCl 4, AlBr 3) are effective. A host of mixed anhydrides and related species readily acylate aryl ethers under mild conditions . Furthermore, catalytic quantities of iron trichloride, iodine, zinc chloride and iron all promote acylations with acid chlorides and anhydrides, although usually at quite high temperatures . A number of novel catalytic systems allow for high yielding ketone synthesis using acid chlorides and anhydrides or carboxylic acids and their TMS derivatives under very mild conditions. Aryl ethers with a further alkyl substituent are generally acylated para to the alkoxy group or ortho if that position is blocked (( 8) and ( 9)). m-Alky...

• References • Fema No: 2097 Sigma-Aldrich • Experimental Physico-chemical Properties • Experimental Melting Point: -37 °C Alfa Aesar -37 °C OU Chemical Safety Data (No longer updated) -37.5 °C Jean-Claude Bradley Open Melting Point Dataset -37 °C Jean-Claude Bradley Open Melting Point Dataset -37 °C Alfa Aesar -37 °C Oakwood -37.5 °C FooDB -37 °C Sigma-Aldrich -37.5 °C Kaye & Laby (No longer updated) -37 °C Oakwood • Experimental Boiling Point: 153-154 °C Alfa Aesar 154 °C OU Chemical Safety Data (No longer updated) 153-154 °C Alfa Aesar 154 °C Oakwood 155 °C FooDB 154 °C Sigma-Aldrich 154 °C / 760 mmHg Kaye & Laby (No longer updated) 154 °C Oakwood • Experimental LogP: 2.11 Egon Willighagen • Experimental Flash Point: 43 °C Alfa Aesar 51 °C OU Chemical Safety Data (No longer updated) 43 °C Alfa Aesar 43 °F (6.1111 °C) Alfa Aesar 43 °C Oakwood 43 °C Oakwood • Experimental Refraction Index: 1.5168 Alfa Aesar 1.516 Sigma-Aldrich 1.5179 Kaye & Laby (No longer updated) • Experimental Density: 0.994 g/mL / 4 °C Merck Millipore 0.993 g/mL / 20 °C Merck Millipore 0.994 g/mL Alfa Aesar 0.995 g/mL Oakwood 0.995 g/mL Sigma-Aldrich 0.9961 g/mL / 20 °C Kaye & Laby (No longer updated) • Miscellaneous • Appearance: colourless liquid with a pleasant odour OU Chemical Safety Data (No longer updated) • Stability: Stable. Flammable. Incompatible with strong oxidizing agents. OU Chemical Safety Data (No longer updated) • Toxicity: ORL-RAT LD50 3700 mg kg-1, ORL-MUS LD50 2800 mg kg-1 OU Chem...

Catalogue Number Availability Packaging Qty/Pack Price Quantity 8014520100 Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Glass bottle 100 ml Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved ( ) — Request Pricing Added To My Favorites 8014520500 Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Glass bottle 500 ml Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved ( ) — Request Pricing Added To My Favorites 8014521000 Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Glass bottle 1 l Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved ( ) — Request Pricing Added To My Favorites 8014522500 Retrieving availability... — Limited Availability In Stoc...