Celiac disease treatment

Caption: Fly into new horizons! Image: CC BY 2.0--Sunny M5 Celiac.com 06/10/2023 - If you suffer from celiac disease like I do you are well aware that the current and only treatment recommended for the disease is a lifelong adherence to a strict gluten-free diet. Anyone who has tried a gluten-free diet knows that it works fine as a treatment for the disease, but it also can be difficult to deal with, especially when cooking, dining out, and buying food (it can also be expensive!). According to one line of research done over the past few years, however, there may be hope that one day in the not too distant future we might be able to eat gluten without harm. How—you ask? Immunotherapy In 2001 the Scandinavian Journal of Immunology published an article authored by a group of Italian scientists wherein mice were used to test a new idea called immunomodulation and its ability to treat celiac disease. The scientists purified the protein gliadin (the component of gluten that triggers immune-mediated injury when ingested by people with celiac disease), fractionated it, and then administered the different fragments intra-nasally to laboratory mice (presumably transgenic mice with induced celiac disease, although this is unclear) and noted the results. They found that when a particular fragment of gliadin, which they refer to as alpha-gliadin, was administered intra-nasally it down-regulated T-cell proliferation and interferon-gamma production in response to whole gliadin in vitro. ...

Are you looking for a potential new celiac disease treatment? The LILY Study is a phase 1 celiac disease study that will measure the safety of the study medication, DONQ52, for targeting an immune complex known to cause celiac disease symptoms. There is no gluten challenge in this study. You may be compensated for time and travel. Study Requirements: • You are 18-70 years old • You have celiac disease • You are already on a gluten-free diet for at least 12 months • Have or can obtain medical records which show diagnosis of celiac disease • Other requirements will apply. Study Site Locations: • Multisite (US) If you’re interested in the study, think you may qualify, or want to find a study site location near you, visit Tags:

Eric Audras/ Getty Images Gluten exposure leads to a dreary combination of It's tough to feel normal when you can't sleep at nightand only want to sleep during the day. The solution? Get as much rest as you possibly can—whenever you can grab it. If you're lucky enough to work at home, or if you have a flexible schedule, try to build in time for a daily 20-minute nap. Even if you can't actually sleep, lying down and simply resting with your eyes closed may help. Try breathing deeply to clear your mind of any gluten-induced anxiety as you rest. Les and Dave Jacobs/Getty Images You may experience Needless to say, that's not a good combination for tasks that involve decision-making or deep analysis. If you're feeling the effects of gluten contamination, try to avoid those types of tasks. Reschedule what you possibly can. If you can't (which is the case for many), use plenty of caution when performing potentially dangerous tasks. Extra sleep (again, if you can manage it) can help with brain fog. In most cases, though, you'll just have to wait for it to lift. Lactose intolerance is common in people with celiac disease, especially among those newly diagnosed with celiac. However, many people report that they're better able to digest dairy again once they've followed a Lactose intolerance related to glutening is usually only temporary. Just make sure to avoid milk and products that contain milk such as yogurt, ice cream, and soft cheese until you feel recovered. If your lactose in...