Clonazepam uses

Continuing Education Activity Clonazepam is a benzodiazepine drug used for the acute treatment of panic disorder, epilepsy, and nonconvulsive status epilepticus. The drug also has many off-label indications, including restless leg syndrome, acute mania, insomnia, and tardive dyskinesia. Clonazepam is a long-acting and high-potency benzodiazepine; it behaves as a GABA-A receptor agonist. Benzodiazepines facilitate GABA-A action by increasing the frequency of chloride channel opening resulting in hyperpolarization of the neurons and reduced firing, thus producing calming effects on the brain by decreasing the excitability of neurons. Clonazepam also has serotonergic activity by increasing serotonin synthesis. This activity will highlight the indications, mechanism of action, administration, adverse event profile, contraindications, monitoring, and toxicity of clonazepam in the clinical settings pertinent for interprofessional team members in treating patients with panic and seizure disorders. Objectives: • Identify the indications for using clonazepam therapy. • Select patients who will benefit from clonazepam therapy. • Coordinate the management of a patient with clonazepam toxicity. • Collaborate with the interprofessional team to monitor patients for clonazepam overdose and/or toxicity to improve outcomes and prevent the risk of developing severe side effects. Indications Clonazepam is a long-acting and high-potency benzodiazepine. It behaves as a GABA-A receptor agonist....

What is this medication? CLONAZEPAM (kloe NA ze pam) treats seizures. It may also be used to treat panic disorder. It works by helping your nervous system calm down. It belongs to a group of medications called benzodiazepines. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Ceberclon, Klonopin What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • An alcohol or drug abuse problem • Bipolar disorder, depression, psychosis or other mental health condition • Glaucoma • Kidney or liver disease • Lung or breathing disease • Myasthenia gravis • Parkinson disease • Porphyria • Seizures or a history of seizures • Suicidal thoughts • An unusual or allergic reaction to clonazepam, other benzodiazepines, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? Take this medication by mouth with a glass of water. Follow the directions on the prescription label. If it upsets your stomach, take it with food or milk. Take your medication at regular intervals. Do not take it more often than directed. Do not stop taking or change the dose except on the advice of your care team. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team regarding the use of this medication...

See also Warning section. Read the Take this medication by Do not remove the tablet from its pouch until you are ready to take it. Dry your hands before handling the medication. Open the pouch and peel back the foil layer. Do not push the tablet through the foil because it may get damaged. Place the dose in your Dosage is based on your medical condition, age, and response to treatment. For children, the dose is also based on Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details. If you have several different types of Tell your doctor if your condition lasts or gets worse. See also Warning section. Drowsiness, Remember that this A small number of people who take anticonvulsants for any condition (such as A very serious This is not a complete list of possible side effects. If you notice other ef...

Clonazepam (Klonopin) is one of the most popular members of Klonopin has remained one of the most commonly prescribed medications in the US for over 20 years. As of 2019, Klonopin was listed as the 46th most prescribed medication in the US. The drug is habit-forming, which means that misuse of clonazepam can cause addiction. It’s thought to be more euphoric and less sedative than other drugs of the same class. Some recreational users refer to this drug as the “MDMA of the benzo world.” A large number of young people abuse clonazepam for its euphoric properties. Studies support the idea that long-term use of Klonopin leads to issues with cognition (learning and memory), immune health, and rebound insomnia and anxiety. Clonazepam was first patented in 1960 by Roche and later approved by the Food and Drug Administration (FDA) in 1975. The patent for clonazepam expired long ago, and there are now many generic versions of the drug sold under different names [ Clonazepam Specs Status Approved 💊 Common Dosage 0.5–1 mg PubChem ID CAS# IUPAC Name: 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepine-2-one Other Names: Rivatril, Rivotril, Klonopin, Iktorivil, Paxam Metabolism Clonazepam is primarily metabolized into inactive metabolites by the cytochrome P450 enzymes, including the CYP3A4 enzyme. Because it is lipid-soluble, it can easily cross the placenta and the blood-brain barrier [ Duration of Effects Intermediate-Acting (9.5–50 hours). The half-life of clonazepam ranges b...

Proper Use Drug information provided by: Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence). This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Swallow the tablet whole with water. If you are using the disintegrating tablet (wafer), make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may take a sip of water. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you...

clonazepam, drug used to treat Clonazepam was developed in the early 1960s by Austro-Hungarian-born American chemist Leo Sternbach and his colleagues at the pharmaceutical company Hoffmann-La Roche. It was approved by the U.S. Clonazepam works bybinding to thegamma-aminobutyric acidA (GABA A) In addition to its use in the management of panic and seizure disorders, clonazepam is sometimes also used in the treatment of seizures in children, particularly petit mal absences, as well as for certain anxiety-related disorders, such as

• This drug is a benzodiazepine. The use of a benzodiazepine drug along with opioid drugs has led to very bad side effects. Side effects that have happened include slowed or trouble breathing and death. Opioid drugs include drugs like codeine, oxycodone, and morphine. Opioid drugs are used to treat pain and some are used to treat cough. Talk with the doctor. • If your child is taking this drug with an opioid drug, get medical help right away if your child feels very sleepy or dizzy; if your child has slow, shallow, or trouble breathing; or if your child passes out. Get medical help right away if your child does not respond, does not answer or react like normal, or will not wake up. • Benzodiazepines can put your child at risk for addiction, abuse, and misuse. Misuse or abuse of this drug can lead to overdose or death, especially when used along with certain other drugs, alcohol, or street drugs. Addiction can happen even if your child takes this drug as told by the doctor. Get medical help right away if your child has changes in mood or behavior, suicidal thoughts or actions, seizures, or trouble breathing. • Your child will be watched closely to make sure your child does not misuse, abuse, or become addicted to this drug. • Benzodiazepines may cause dependence. Lowering the dose or stopping this drug all of a sudden may cause withdrawal. This can be life-threatening. The risk of dependence and withdrawal are raised the longer your child takes this drug and the higher the ...