Ct value full form in corona report in hindi

There is little choice with us in the pandemic times, but to increase our awareness around scientific terms that can have a bearing on us. One such terminology referred to as ‘CT Value’ has become popular as the viral disease swept the country leading to deaths. The ‘Ct value’ indicated in RT-PCR tests basically helps in determining whether a patient is Covid-19 positive or not. In fact, the Maharashtra government has recently sought clarity from the Indian Council of Medical Research (ICMR) on this subject. Also Read: As per the Indian Express report, the state wanted to understand if a person can be considered Covid-negative with the Ct value more than 24 and the person is asymptomatic. The ICMR DG responded back based on the inputs from virology laboratories across the country after which it arrives at a single Ct value cut-off. What is the CT value in the RT-PCR report? At the time of an RT-PCR test, the Naso-Laryngeal swabs is taken from the suspected Covid-19 patient after which there are cycles of tests carried out on the sample. The patient is tested positive based on the cycle threshold (CT) value which is the number of cycles after which the virus can be detected. It works as a criterion to check how soon after an RT-PCR test, the SARS-CoV-2 is detected in a sample. Scientifically, a CT value signals the number of cycles for a sample to go through to amplify and bring up the viral DNA to a traceable level under given settings, according to the American Associatio...

Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. Flu

Science's COVID-19 reporting is supported by the Pulitzer Center and the Heising-Simons Foundation. Ever since the coronavirus pandemic began, battles have raged over testing: Which tests should be given, to whom, and how often? Now, epidemiologists and public health experts are opening a new debate. They say testing centers should report not just whether a person is positive, but also a number known as the cycle threshold (CT) value, which indicates how much virus an infected person harbors. Advocates point to new research indicating that CT values could help doctors flag patients at high risk for serious disease. Recent findings also suggest the numbers could help officials determine who is infectious and should therefore be isolated and have their contacts tracked down. CT value is an imperfect measure, advocates concede. But whether to add it to test results "is one of the most pressing questions out there," says Michael Mina, a physician and epidemiologist at Harvard University's T.H. Chan School of Public Health Standard tests identify SARS-CoV-2 infections by isolating and amplifying viral RNA using a procedure known as the polymerase chain reaction (PCR), which relies on multiple cycles of amplification to produce a detectable amount of RNA. The CT value is the number of cycles necessary to spot the virus; PCR machines stop running at that point. If a positive signal isn't seen after 37 to 40 cycles, the test is negative. But samples that turn out positive can star...

What is the N gene? How do I know if I have tested positive for the delta variant or the omicron variant? How to check the Ct value? These are very common questions people ask each other the moment they download the COVID-19 test report. It is very important to understand what a COVID-19 test report holds so that one can know the severity of the infection. What is the N gene? How do I know if I have tested positive for the delta variant or the omicron variant? How to check the Here we have decoded the COVID-19 test report step by step: ORF1ab: This collectively refers to the open reading frames, ORF1a and ORF1b, found in genomes of coronaviruses. They encode polyprotein 1a, b which are involved in N gene: In simple words, N gene or Nucleocapsid is a type of structural protein of coronavirus. "Nucleocapsid proteins of several viruses have been demonstrated to play multiple regulatory roles during viral pathogenesis. They are equipped with specific structural motifs and/or signature sequences, by which they associate with other viral/ host factors and skew the host cellular machinery in such a manner that it becomes more favorable for the survival of the virus," says a research study. It’s a potential target for the detection of the virus. During the intracellular life cycle, COVID-19 inducing coronavirus replicates its genomic RNA. Currently, the detection of coronavirus is done by real-time RT-PCR detection of two target genes, the open reading frame of 1ab (ORF1ab) and th...

Dr Shahid Jameel, Virologist and Director at Trivedi School of Biosciences, Ashoka University, reveals in a conversation with FIT, that the RT-PCR test, ie, polymerase chain reaction test, examines the viral DNA or RNA to check the amount of molecules in it. There are many cycles in this test. DNA or RNA molecules are doubled in every cycle. These tests are amplification tests - because the molecules in the sample are very small, the virus can be detected only after amplification in some cycles. The CT value indicates the number of cycles needed for the virus to be detected. Due to amplification, a negative sample also starts giving non-specific positive signals in 40 cycles. Therefore, if the number is less than 40, the sample is considered positive. It is being claimed in many news reports that even if the report is positive for the RT-PCR test, patients who have a CT value of more than 24 will not spread the infection. Dr. Shahid Jameel falsifies such claims. He says that if someone with a CT value of 30 is roaming without a mask, then they are more likely to spread the virus than an infected person with a 22 CT value who stays isolated. In such a situation, fixing the cutoff at 24 can mislead people. The ICMR clearly states that it does not recommend COVID-19 patients to rely on numerical CT values to determine infectiousness and patient management protocols. The guideline states- • There are no reliable studies to definitively prove a direct correlation between diseas...

A term related to the ‘gold standard’ RT-PCR tests to detect the novel coronavirus has got a lot of attention – the ‘Cycle Threshold’ value. From a viral video by an Indian cardiologist, to Biocon’s head Kiran Mazumdar Shaw, everyone is talking about Cycle Threshold value and its role in deciding whether you can infect someone else or how contagious you are. Dr Shahid Jameel, Virologist and Director at Trivedi School of Biosciences, Ashoka University falsifies such claims. He says that if someone with a CT value of 30 is roaming around without a mask, then they are more likely to spread the virus than an infected person with a 22 CT value who stays isolated. In such a situation, fixing the cutoff at 24 can mislead people, he told FIT. Patients in early symptomatic stage may show a high CT value which may subsequently change. CT values differ from one kit to the other. Comparability of CT values among different kits is a challenge as our labs are using a mixed basket of kits now with different CT cut-offs and different gene targets.

Amid the ongoing second wave of the pandemic, as states are conducting a higher number of Rt-PCR tests, people are now aware of a new term, called CT value, a score written on the RT-PCR report, if the outcome of the test is positive. According to ICMR documents, CT value is the cycle threshold value, which is "inversely proportional" to viral load, which means the lower the number higher the viral load and vice versa. But the value can differ from one kit to another and the viral load does not have much role in patient management, the ICMR has said. A health worker collects a swab sample from a woman for the Covid-19 test in Kanpur. (PTI) Dr Hemant Deshmukh of Mumbai's King Edward Memorial Hospital has said if the value is over 35, then it is considered a negative result and when the value is below negative, the result is considered positive. The number suggests the number of cycle after which the virus has been detected. So in general, if the CT Score is, for example, 20, it means the virus is spotted in 20 cycles, thus implying that the load is higher than a score, for example, 30. '1 CT scan is equivalent to 300 chest X-rays', Guleria warns against risk of cancer "But whatever the value is, be it 10 or 28, an infected person can spread the virus," Dr Deshmukh said. What is CT Scan score? Dr Deshmukh said doctors may advise CT Scan if a patient does not get cured of fever or cough after medicine. A CT scan score of 5 out of 25 is considered normal. "If the score is more...