Dicyclomine hydrochloride and activated dimethicone suspension

Background We describe a “stability-indicating liquid chromatography” technique for the estimation of dimethicone (DEC) and dicyclomine hydrochloride (DEH) in the established tablet formulations. Individual quantification of DEH and DEC was reported. But simultaneous quantification of DEH and DEC was lacking. DEH and DEC were analysed on an “XTerra C 18 column (250 mm × 4.6 mm, 5 μm)” with the mobile phase solvent run isocratically with 0.1M K 2HPO 4-acetonitrile (55:45, v/v) on a flow speed of 1.0 mL/min. Results The chromatographic run period for the DEC and DEH assay was 6.0 min with retention times of 2.134 and 2.865 min, respectively. The method was validated for accuracy (99.453 to 100.417% and 99.703 to 100.303% recovery values for DEH and DEC, respectively), precision (RSV value 0.135% for DEC and 0.171% for DEH), linearity (5–15 μg/mL for DEH and 20–60 μg/mL for DEC), selectivity (no hinderance from excipients) and specificity (no hinderance from degradants) recovery. Conclusion The developed stability-indicating liquid chromatography process was well applied to established tablet formulations. Instruments Chromatographic analysis of DEH and DEC was performed employing “Waters HPLC system” furnished with quaternary pump, autosampler, column oven and degasser. UV spectrometric detection operated at 265 nm was used for DEH and DEC detection and quantitation. Hardware regulation, data acquisition and management were done using “Waters Empower 2â...

We are engaged in manufacturing and supplying supreme quality Dicyclomine HCL. & Activated Dimethicone Suspension. Offered drop is used to cure diseases related to ear and eye. Processed in execution with set medical industry norms using high grade substances, offered drop is tested on various quality parameters. We offer this drop in various quantity packing options at very realistic rates to the clients. Features: Accurate composition * No side effects We are engaged in manufacturing and supplying supreme quality Dicyclomine HCL. & Activated Dimethicone Suspension. Offered drop is used to cure diseases related to ear and eye. Processed in execution with set medical industry norms using high grade substances, offered drop is tested on various quality parameters. We offer this drop in various quantity packing options at very realistic rates to the clients. Features: • Accurate composition • No side effects • Purity • Safe consumption TICO-SPAS Dimethicone-40mg+dicyclomine-10 mg 15ML GST 03AAEFT5826F1ZD Established in the year 2006, at Dera Bassi (Punjab, India), we, “ Ticoma Pharmacia,” are a leading manufacturer and supplier of a wide range of Pharmaceutical Tablets, Cough Syrup, Capsules, Ointment or Gel, Injections, Pediatric Drops, Tonic, Dry Syrup, Ear & Eye Drops, etc. We have spare capacity, for 3rd Party, Contract manufacturing in Tablets, Capsules & Liquid Oral In Beta Lactum & Non Beta Lactum. Offered drugs are hygienically processed & formulated under the superv...

Unknown ఇతర మందులతో Dicyclomine + Dimethicone యొక్క తీవ్ర పరస్పర చర్య - Dicyclomine + Dimethicone Severe Interaction with Other Drugs in Telugu - itara mamdulato Dicyclomine + Dimethicone yokka teevra paraspara charya రోగులకు ఇది తీవ్రమైన దుష్ప్రభావాలను కలిగించవచ్చు కాబట్టి, ఈ క్రింది మందులతో కలిపి Dicyclomine + Dimethicone ను తీసుకోకూడదు - Paracetamol • • • • Caffeine • • • • Codeine • • • • Pseudoephedrine • • • • Dextromethorphan • • • • Phenylephrine • • • • Atenolol • • • • Ipratropium • • • • Dicyclomine + Dimethicone యొక్క వైరుధ్యములు - Dicyclomine + Dimethicone Contraindications in Telugu - Dicyclomine + Dimethicone yokka varidhyamulu మీరు గనక ఈ క్రింది వ్యాధులలో దేనితోనైనా బాధపడుతూ ఉన్నట్లయితే, మీ డాక్టరు గారు అలా చేయమని సలహా ఇస్తే తప్ప, మీరు Dicyclomine + Dimethicone ను తీసుకోకూడదు - • Dicyclomine + Dimethicone గురించి తరచుగా అడిగే ప్రశ్నలు - Frequently asked Questions about Dicyclomine + Dimethicone in Telugu - Dicyclomine + Dimethicone gurinchi tarachugaa adige prashnalu

Related/similar drugs DOSAGE & ADMINISTRATION Dosage must be adjusted to individual patient needs. Oral Dosage and Administration in Adults The recommended initial dose is 20 mg four times a day. After one week treatment with the initial dose, the dose may be increased to 40 mg four times a day unless side effects limit dosage escalation. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued. Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks. DOSAGE FORMS & STRENGTHS Dicyclomine hydrochloride oral solution 10 mg/5 mL Contraindications Dicyclomine hydrochloride is contraindicated in infants less than 6 months of age [ see Use in Specific Populations (8.4)], nursing mothers [ see Use in Specific Populations (8.3)], and in patients with: • unstable cardiovascular status in acute hemorrhage • myasthenia gravis [ see Warnings and Precautions (5.4)] • glaucoma [ see Adverse Reactions (6.3) and Drug Interactions (7.1)] • obstructive uropathy [ see Warnings and Precautions (5.8)] • obstructive disease of the gastrointestinal tract [ see Warnings and Precautions (5.5)] • severe ulcerative colitis [ see Warnings and Precautions (5.7)] • reflux esophagitis Warnings and Precautions Cardiovascular Conditions Dicyclomine hydrochloride needs to be used with caution in conditions characterized by tachyarrhythmia such as thyrotoxicosis, congestive heart failure and in ...

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