Dr hargobind khorana

Who was Har Gobind Khorana? Har Gobind Khorana was a legendary Indian biochemist (acquired American citizenship later). Har Gobind Khorana is one of the few people of Indian origin to ever win the Nobel Prize. He won the 1968 Nobel Prize for Medicine/Physiology along with his colleagues from the University of Wisconsin-Madison, Marshall W. Nirenberg and Robert W. Holley. Har Gobind Khorana and his fellow Nobel laureates conducted ground breaking research which displayed the order of nucleotides within nucleic acid molecules. These nucleotides perform the function of cellular protein synthesis as well as carry the genetic code for each cell. Har Gobind Khorana and fellow laureate Marshall Nirenberg were also awarded with Columbia University’s prestigious Gross Horwitz Prize in the same year as their Nobel prize. Har Gobind Khorana was born before India’s independence and partition and went on to work as faculty at three prestigious universities in North America. Har Gobind Khorana also became a naturalized citizen of the United States States of America in 1966. For his achievements and contributions in the field of science as an American, Har Gobind Khorana was bestowed with the prestigious National Medal of Science in 1987. One of his favourite quotes was Otto Loewi’s “we must be modest except in our aims”. Where was Har Gobind Khorana born? Har Gobind Khorana was born on January 9 th, 1922 in Raipur (not to be confused with Raipur in modern day India’s Chhattisgarh), Mult...

• Full Name: Har Gobind Khorana • Known For: Research showing the role of nucleotides in the synthesis of proteins and the first artificial synthesis of a complete gene. • Born: January 9, 1922 in Raipur, Punjab, British India (now Pakistan) • Parents: Krishna Devi and Ganpat Rai Khorana • Died: November 9, 2011 in Concord, Massachusetts, USA • Education: Ph.D., University of Liverpool • Key Accomplishments: Nobel Prize for Physiology or Medicine in 1968 • Spouse: Esther Elizabeth Sibler • Children: Julia Elizabeth, Emily Anne, and Dave Roy Early Years Har Gobind Khorana was likely born to Krishna Devi and Ganpat Rai Khorana on January 9, 1922. While that is his officially recorded date of birth, there is some uncertainty as to whether or not that was his exact date of birth. He had four siblings and was the youngest of the five children. His father was a taxation clerk. While the family was poor, his parents realized the value of educational attainment and Ganpat Rai Khorana ensured that his family was literate. By some accounts, they were the only literate family in the area. Khorana attended the D.A.V. High School and then matriculated to Punjab University where he earned both a Bachelor's (1943) and a Master's degree (1945). He distinguished himself in both instances and graduated with honors for each degree. Subsequently he was awarded a fellowship from the government of India. He used the fellowship to earn his Ph.D. in 1948 from the University of Liverpool in Englan...

Throughout his career, Har Gobind Khorana was devoted to working in the lab himself. When his lab undertook a new research direction, he insisted on knowing how to master the relevant experimental methods with his own hands. Khorana is shown here conducting a DNA polymerase assay at the University of Wisconsin. Photo: University of Wisconsin-Madison Archives (S04437). The rise of the information age in the second half of the 20th centurywas spurred on by two related but distinct scientific and technologicalrevolutions. The first, of course, was the digital revolution, whichemerged with the development of the mathematics necessary forcomputation and data storage based entirely on a binary code. Thesecond revolution came about from the discovery that information encoded in the molecular sequence of DNA carries the instructions forthe working parts of a cell and thus is the blueprint of life. The field ofmolecular biology emerged as the study of how genetic information istransmitted from one generation to another and is read out to form functional cellular components and regulatory circuits. The foundational science of molecular biology has led to methodsfor reading and writing biological information and to alter genomesby design. The capability to reprogram living organisms to do usefulthings forms the basis of the biotechnology industry. No single institution has had a greater impact in accelerating therevolution in molecular biology and biotechnology than MIT. Theorigins o...

The divisions that have plagued the land of the five rivers – divisions over religion, national boundaries, war, diplomacy, cricket – have been the focus of the energies of our people for the 75 years since Independence. But if we can bring ourselves to move past the superficialities of these divisions, our shared legacies and heritage – of food, language, literature, geography, music – are far more profound and historical. Today, I wish to highlight one such shared heritage. A century ago on January 9, 1922, in the dusty village of Raipur, in Multan District – a village so small only about a hundred people could lay claim to residing there – my great-grandmother gave birth to her youngest son, whom they called Har Gobind. Our family came from poverty, although the meaning of our last name Khorana (alternatively spelt Khurana) perhaps reflects a time when we were “rich” enough to own a well. My great-grandfather, the family patriarch, was a patwari – a village clerk occupying the lowest rung in the agricultural revenue collection system set up by the ruling colonial government. Few records have survived the times, so we know little of how the boy Gobind grew up, although family lore speaks of a mischievous child who liked to steal sugarcane from the sugarcane fields. Gobind described our ancestral home as consisting of a kitchen and bedrooms in one corner, with a courtyard housing cows and horses on the opposite end. Raipur at the time had no schools to speak of, so my gre...

Dr. M. Gowri Sankar, MD, Senior Assistant Professor, Dept. of General Medicine, Government Medical College and ESI Hospital, Coimbatore. Today’s History Feature: 🇮🇳 Dr. Har Gobind Khorana🇮🇳 (Jan 9, 1922 – Nov 9, 2011) 💠Indian- American Biochemist 💠Father of Genetic Engineering His contributions… 🔹Har Gobind Khorana was born ina village called Raipur inPunjab inBritish India. 🔹His parents were native Indians and his father was a village Agricultural Taxation Clerk in the British Indian government. His family was the only literate family in the village at that time. 🔹Khorana completed his Bachelor degree and Master of Science from the Punjab University with the help of scholarship. 🔹Then he moved to England to study organic chemistry at the University of Liverpoolon a Government of India Fellowship. He completed his PhD in 1948. 🔹After completion of his studies, he received a job offer from Dr. Gordon M. Shrum, a Canadian scientist in the University of British Columbia. Khorana was actually inspired by him so he wanted to involve himself in all of his researches. 🔹In 1960, Khorana accepted the Job position offered by the Institute for Enzyme Research at the University of Wisconsin. By the support of his team of researchers, Khorana was very successful in developing the methods for synthesizing phosphateesterderivatives of nucleic acids. 🔹Subsequently, he collaborated with John G. Moffatt in the year1959 and discovered thesynthesisof acetyl coenzyme A (acetyl CoA) – it’s amol...

Who was Har Gobind Khorana? Har Gobind Khorana was a legendary Indian biochemist (acquired American citizenship later). Har Gobind Khorana is one of the few people of Indian origin to ever win the Nobel Prize. He won the 1968 Nobel Prize for Medicine/Physiology along with his colleagues from the University of Wisconsin-Madison, Marshall W. Nirenberg and Robert W. Holley. Har Gobind Khorana and his fellow Nobel laureates conducted ground breaking research which displayed the order of nucleotides within nucleic acid molecules. These nucleotides perform the function of cellular protein synthesis as well as carry the genetic code for each cell. Har Gobind Khorana and fellow laureate Marshall Nirenberg were also awarded with Columbia University’s prestigious Gross Horwitz Prize in the same year as their Nobel prize. Har Gobind Khorana was born before India’s independence and partition and went on to work as faculty at three prestigious universities in North America. Har Gobind Khorana also became a naturalized citizen of the United States States of America in 1966. For his achievements and contributions in the field of science as an American, Har Gobind Khorana was bestowed with the prestigious National Medal of Science in 1987. One of his favourite quotes was Otto Loewi’s “we must be modest except in our aims”. Where was Har Gobind Khorana born? Har Gobind Khorana was born on January 9 th, 1922 in Raipur (not to be confused with Raipur in modern day India’s Chhattisgarh), Mult...

• Full Name: Har Gobind Khorana • Known For: Research showing the role of nucleotides in the synthesis of proteins and the first artificial synthesis of a complete gene. • Born: January 9, 1922 in Raipur, Punjab, British India (now Pakistan) • Parents: Krishna Devi and Ganpat Rai Khorana • Died: November 9, 2011 in Concord, Massachusetts, USA • Education: Ph.D., University of Liverpool • Key Accomplishments: Nobel Prize for Physiology or Medicine in 1968 • Spouse: Esther Elizabeth Sibler • Children: Julia Elizabeth, Emily Anne, and Dave Roy Early Years Har Gobind Khorana was likely born to Krishna Devi and Ganpat Rai Khorana on January 9, 1922. While that is his officially recorded date of birth, there is some uncertainty as to whether or not that was his exact date of birth. He had four siblings and was the youngest of the five children. His father was a taxation clerk. While the family was poor, his parents realized the value of educational attainment and Ganpat Rai Khorana ensured that his family was literate. By some accounts, they were the only literate family in the area. Khorana attended the D.A.V. High School and then matriculated to Punjab University where he earned both a Bachelor's (1943) and a Master's degree (1945). He distinguished himself in both instances and graduated with honors for each degree. Subsequently he was awarded a fellowship from the government of India. He used the fellowship to earn his Ph.D. in 1948 from the University of Liverpool in Englan...

Dr. M. Gowri Sankar, MD, Senior Assistant Professor, Dept. of General Medicine, Government Medical College and ESI Hospital, Coimbatore. Today’s History Feature: 🇮🇳 Dr. Har Gobind Khorana🇮🇳 (Jan 9, 1922 – Nov 9, 2011) 💠Indian- American Biochemist 💠Father of Genetic Engineering His contributions… 🔹Har Gobind Khorana was born ina village called Raipur inPunjab inBritish India. 🔹His parents were native Indians and his father was a village Agricultural Taxation Clerk in the British Indian government. His family was the only literate family in the village at that time. 🔹Khorana completed his Bachelor degree and Master of Science from the Punjab University with the help of scholarship. 🔹Then he moved to England to study organic chemistry at the University of Liverpoolon a Government of India Fellowship. He completed his PhD in 1948. 🔹After completion of his studies, he received a job offer from Dr. Gordon M. Shrum, a Canadian scientist in the University of British Columbia. Khorana was actually inspired by him so he wanted to involve himself in all of his researches. 🔹In 1960, Khorana accepted the Job position offered by the Institute for Enzyme Research at the University of Wisconsin. By the support of his team of researchers, Khorana was very successful in developing the methods for synthesizing phosphateesterderivatives of nucleic acids. 🔹Subsequently, he collaborated with John G. Moffatt in the year1959 and discovered thesynthesisof acetyl coenzyme A (acetyl CoA) – it’s amol...

The divisions that have plagued the land of the five rivers – divisions over religion, national boundaries, war, diplomacy, cricket – have been the focus of the energies of our people for the 75 years since Independence. But if we can bring ourselves to move past the superficialities of these divisions, our shared legacies and heritage – of food, language, literature, geography, music – are far more profound and historical. Today, I wish to highlight one such shared heritage. A century ago on January 9, 1922, in the dusty village of Raipur, in Multan District – a village so small only about a hundred people could lay claim to residing there – my great-grandmother gave birth to her youngest son, whom they called Har Gobind. Our family came from poverty, although the meaning of our last name Khorana (alternatively spelt Khurana) perhaps reflects a time when we were “rich” enough to own a well. My great-grandfather, the family patriarch, was a patwari – a village clerk occupying the lowest rung in the agricultural revenue collection system set up by the ruling colonial government. Few records have survived the times, so we know little of how the boy Gobind grew up, although family lore speaks of a mischievous child who liked to steal sugarcane from the sugarcane fields. Gobind described our ancestral home as consisting of a kitchen and bedrooms in one corner, with a courtyard housing cows and horses on the opposite end. Raipur at the time had no schools to speak of, so my gre...

Throughout his career, Har Gobind Khorana was devoted to working in the lab himself. When his lab undertook a new research direction, he insisted on knowing how to master the relevant experimental methods with his own hands. Khorana is shown here conducting a DNA polymerase assay at the University of Wisconsin. Photo: University of Wisconsin-Madison Archives (S04437). The rise of the information age in the second half of the 20th centurywas spurred on by two related but distinct scientific and technologicalrevolutions. The first, of course, was the digital revolution, whichemerged with the development of the mathematics necessary forcomputation and data storage based entirely on a binary code. Thesecond revolution came about from the discovery that information encoded in the molecular sequence of DNA carries the instructions forthe working parts of a cell and thus is the blueprint of life. The field ofmolecular biology emerged as the study of how genetic information istransmitted from one generation to another and is read out to form functional cellular components and regulatory circuits. The foundational science of molecular biology has led to methodsfor reading and writing biological information and to alter genomesby design. The capability to reprogram living organisms to do usefulthings forms the basis of the biotechnology industry. No single institution has had a greater impact in accelerating therevolution in molecular biology and biotechnology than MIT. Theorigins o...