Estradiol

Your body needs estrogen for your reproductive, cardiovascular and bone health. Too much estrogen, though, can cause irregular periods and may worsen conditions that affect your reproductive health. Your provider can help diagnose what’s causing your high estrogen levels and recommend treatments that can help. Overview What does it mean to have high estrogen? Estrogen is an important hormone that regulates your Estrogen levels that are too high or cause a hormone imbalance can cause problems. High estrogen can disrupt reproductive processes, cause unpleasant symptoms and increase your risk of certain conditions. What is estrogen dominance? Estrogen and progesterone work well together to prevent the lining of your uterus from getting too thick. Some people’s bodies don’t make enough progesterone, leading to what’s called unopposed estrogen. Unopposed estrogen is called estrogen dominance in some medical literature. Without progesterone’s balancing influence, estrogen can work overtime in your body and cause cell overgrowths, like tumors in your uterine lining. How does high estrogen affect the body of a woman or AFAB person? It’s rare for your levels to be high because of the estrogen you’re producing. It’s more likely that your estrogen levels are high because of medications you’re taking. For instance, you may have a low sex drive because of high estrogen levels, but this is most likely caused by your birth control pills — not your body’s natural estrogen. Elevated estrog...

What is estradiol vaginal (systemic)? Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal This medication guide provides information about estradiol vaginal for systemic treatment of certain symptoms of menopause, including hot flashes and Estradiol vaginal (systemic) may also be used for purposes not listed in this medication guide. Warnings You should not use estradiol vaginal if you have: undiagnosed vaginal bleeding, liver disease, a Do not use if you are pregnant. Estradiol may increase your risk of developing a condition that may lead to Report any unusual vaginal bleeding right away. Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Estradiol should not be used to prevent heart disease, stroke, or Related/similar drugs Before taking this medicine You should not use estradiol if you are allergic to it, or if you have: • unusual vaginal bleeding that has not been checked by a doctor; • liver disease; • a history of heart attack, stroke, or blood clot; • an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or • a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina. Do not use estradiol if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more a...

What is this medication? ESTRADIOL (es tra DYE ole) reduces vaginal irritation, dryness, and pain during sex due to menopause. It is an estrogen hormone. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Estrace What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • Abnormal vaginal bleeding • Blood vessel disease or blood clots • Breast, cervical, endometrial, ovarian, liver, or uterine cancer • Dementia • Diabetes • Gallbladder disease • Heart disease or recent heart attack • High blood pressure • High cholesterol • High levels of calcium in the blood • Hysterectomy • Kidney disease • Liver disease • Migraine headaches • Protein C/S deficiency • Stroke • Systemic lupus erythematosus (SLE) • Tobacco smoker • An unusual or allergic reaction to estrogens, other hormones, soy, other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? This medication is for use in the vagina only. Do not take by mouth. Follow the directions on the prescription label. Read package directions carefully before using. Use the special applicator supplied with the cream. Wash hands before and after use. Fill the applicator with the prescribed amount of cream. Lie on your back, part and bend your knees. Insert the applicator into the vagina and push the plunger to expel the ...

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, breast, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water. This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions. Wash your hands with soap and water before and after using this medicine. To use the patch: • Wash your hands with soap and water before and after you use this medicine. • Carefully tear open the pouch when you are ready to put the patch on your skin. Do not cut it. • Peel off the backing from the patch and apply the patch to a clean, dry, and hair-free area of the lower stomach or upper buttock area. This area must be free of powder, oil, or lotion for the patch to stick on to your skin. • Press the patch firmly in place with your hand for about 10 seconds. • Do not apply the patch on the breast or over any skin folds. Do not apply the patch on oily, broken, burned, or irritated skin, or areas with skin conditions (eg, birth marks, tattoos). Avoid applying the patch on the waistline or other places where tight clothing may rub it off. • Wear the patch at all times until it is time to put on a new patch. Do not expose it to the sun for long periods of time. • When replacing your patch, make sure to apply the new patch to a different area of your lower abdomen. Wait at least 1 week before app...

Estradiol: 7 things you should know Medically reviewed by • • • • • • • 1. How it works • Estradiol is a synthetic estrogen that may be used to treat symptoms associated with menopause or other conditions that cause low estrogen levels. • Estradiol is the main type of estrogen that circulates naturally in humans. In women with menstrual periods, 70 to 500mcg of natural estradiol is secreted daily, depending on the phase of the menstrual cycle. After menopause, the adrenal cortex secretes a precursor to estrogen called androstenedione, which is converted by peripheral tissues into estrone, which is the most abundant circulating estrogen in postmenopausal women. • Estradiol also plays a critical role in male sexual function being essential for modulating libido, erectile function, and spermatogenesis. • All estrogens act by binding to estrogen receptors in estrogen-responsive tissues. Estrogens work by a negative feedback mechanism to reduce circulating levels of gonadotrophins, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in postmenopausal women. • Estradiol belongs to the class of medicines called estrogens. 2. Upsides • May be used for the treatment of moderate to severe vasomotor symptoms (eg, hot flashes/flushes), and vulvar and vaginal atrophy associated with menopause. However, topical estrogen products are preferred if just prescribing for vulvar and vaginal atrophy. • Treats low estrogen levels associated with hypogonadism, castration, or primary...