H3n2 influenza virus

  1. What Is H3N2 Flu? What You Need to Know About the Deadly Outbreak
  2. Influenza A (H3N2) variant virus
  3. Influenza A virus subtype H3N2
  4. Flu season: These are the most commonly detected strains


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What Is H3N2 Flu? What You Need to Know About the Deadly Outbreak

An outbreak of H3N2 flu in India has left at least two people dead, according to Health experts in India are That said, Sure, with everything we’ve been through over the past three years, it’s understandable to feel a little nervous when you hear about an outbreak. So, do you need to worry about H3N2 in the U.S.? Here’s the deal. What is H3N2? In general, H3N2 is a strain of the flu that you want to avoid, if possible. But experts point out that the U.S. just faced a flu season with H3N2. H3N2 flu viruses began circulating in people in 1968, according to “When you have seasons that are dominated by H3N2, you tend to see more flu-related deaths,” Dr. Adalja says. “H3N2 is a strain of seasonal flu—it has been the dominant strain in this year’s influenza season, including in the U.S.,” Dr. Adalja says. “India just appears to be having a later peak than in the U.S.—H3N2 already came and went in the U.S. flu season.” Story continues Should you be worried about H3N2? Dr. Adalja says it’s unlikely we’ll see H3N2 again this season, despite how rapidly it’s spreading in India. “People have immunity because of exposure” from this season, Dr. Adalja points out. With flu season coming to an end in the U.S., it’s also unlikely that H3N2 would double back, he says. Consider this, too, per Dr. Adalja: H3N2 was Given that H3N2—which is a form of influenza A—was the dominant strain of the flu in the U.S. this season, there is a chance that we could s...

Influenza A (H3N2) variant virus

On 13 January, 2021, a child under 18 years of age in Wisconsin developed respiratory disease. A respiratory specimen was collected on 14 January. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) testing conducted at the Wisconsin State Laboratory of Hygiene indicated a presumptive positive influenza A(H3N2) variant virus infection. The specimen was forwarded to the Influenza Division of the Centers for Disease Control and Prevention (CDC) on 21 January for further testing. On 22 January, CDC confirmed an influenza A (H3N2)v virus infection using RT-PCR and genome sequence analysis. Investigation into the source of the infection has been completed and revealed that the child lives on a farm with swine present. Sampling of the swine on the property for influenza virus has not yet been conducted but is planned. Five family members of the patient reported respiratory illness during the investigation and were tested for influenza; all tested negative. The patient was prescribed antiviral treatment and was not hospitalized and has made a full recovery. No human to human transmission has been identified associated with this investigation. Sequencing of the virus by CDC revealed it is similar to A (H3N2) viruses circulating in swine in the mid-western United States during 2019-2020. Viruses related to this A (H3N2)v virus were previously circulating as human seasonal A (H3N2) viruses until around 2010-2011 when they entered the USA swine population. Thus, past v...

MRNA

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. MRNA-1083 overview mRNA-1083 is under development for the prevention of influenza virus infection caused by influenza A/H1N1, A/H3N2, and influenza B/Yamagata and B/Victoria strains and coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in 18 to 79 years of age group. It is a combination vaccine of mRNA-1283, which encodes Receptor Binding Doman (RBD) and N-Terminal Domain (NTD) of the spike protein and mRNA-1010, which encodes hemagglutinin (HA) glycoproteins of influenza A/H1N1, A/H3N2, and influenza B/Yamagata and B/Victoria-lineages. It is administered through intramuscular route in the form of sterile liquid for injection. Moderna overview For a complete picture of MRNA-1083’s drug-specific PTSR and LoA scores, GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s

Influenza A virus subtype H3N2

The Both the H2N2 and H3N2 The Hong Kong flu strain shared internal genes and the [ citation needed] The Hong Kong flu was the first known outbreak of the H3N2 strain, though there is serologic evidence of H3N2 infections in the late 19th century. The first record of the outbreak in Hong Kong appeared on 13 July 1968 in an area with a density of about 500 people per acre in an urban setting. The outbreak reached maximum intensity in two weeks, lasting six weeks in total. The virus was isolated in By July 1968, extensive outbreaks were reported in Vietnam and Fujian flu (2003–2004) [ ] Fujian flu refers to flu caused by either a Fujian human flu strain of the H3N2 subtype or a Fujian A/Fujian (H3N2) human flu (from A/Fujian/411/2002(H3N2)-like flu virus strains) caused an unusually severe 2003–2004 flu season. This was due to a 2004–2005 flu season [ ] The 2004–05 trivalent influenza vaccine for the United States contained: • an A/New Caledonia/20/99 (H1N1)-like virus • an • a B/Shanghai/361/2002-like virus. 2005–2006 flu season [ ] The • an A/New Caledonia/20/1999-like( • an A/California/7/2004-like( • a B/Jiangsu/10/2003-like viruses 2006–2007 flu season [ ] The 2006–2007 influenza vaccine composition recommended by the World Health Organization on 15 February 2006 and the US FDA's Vaccines and Related Biological Products Advisory Committee on 17 February 2006 used: • an A/New Caledonia/20/99 (H1N1)-like virus • an A/Wisconsin/67/2005 (H3N2)-like virus (A/Wisconsin/67/200...

Flu season: These are the most commonly detected strains

READ: FLU SEASON STARTED IN LAST WEEK OF APRIL The 2023 flu season started in Epidemiologic Week 17 (on 27 April) when the flu detection rate exceeded the The increase in cases was noted in all six provinces where influenza-like illness (ILI) and pneumonia are surveilled. KwaZulu-Natal, Mpumalanga, Gauteng, Western Cape, Eastern Cape, and North West. Influenza percentage detections and epidemic thresholds among cases of all ages, pneumonia surveillance in public hospitals, 01 January 2023 to 28 May 2023. Image: NICD. “As of 28 May 2023, the most commonly detected subtype and lineage is influenza A (H3N2) (146/272, 55%), followed by influenza A (H1N1)pdm09 (116/272, 43%) and, influenza B Victoria (3/272, 1%). 181 samples have subtyping results pending,” said the NICD. Influenza A(H3N2), A(H1N1)pdm09, and influenza B commonly circulate in South Africa seasonally. The NICD said Influenza A(H1N1)pdm09 is sometimes incorrectly referred to as “swine flu” – it has been circulating since its emergence in 2009. “The term ‘swine flu’ should not be used as it causes unnecessary panic. The clinical course of infection and management of this strain is similar to other influenza strains,” said the Institute. SYMPTOMS As previously reported, common flu symptoms include fever, muscle pains, body aches, dry cough, sore throat, runny nose, fatigue, and headache. These symptoms usually present between one to four days after infection and last for two to seven days. In most cases, symptoms re...