Hydroxyzine hydrochloride

Atarax, Vistaril Generic Name Hydroxyzine DrugBank Accession Number DB00557 Background Hydroxyzine is a first-generation histamine H 1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. Type Small Molecule Groups Approved Structure • U.C.B-4492 Pharmacology Indication Hydroxyzine is indicated for the symptomatic relief of anxiety and tension associated with psychoneuroses, and as an adjunct in organic disease states in which anxiety is manifested. Canadian labeling states that hydroxyzine is also indicated in adults and children as a premedication prior to medical procedures, such as dental surgery. Learn more Pharmacodynamics Hydroxyzine blocks the activity of histamine to relieve allergic symptoms such as pruritus. Hydroxyzine is relatively fast-acting, with an onset of effect that occurs between 15 and 60 minutes and a duration of action between 4-6 hours. Mechanism of action The H 1 histamine receptor is responsible for mediating hypersensitivity and allergic reactions. Exposure to an allergen results in degranulation of mast cells and basophils, which then release histamine and other inflammatory mediators. Histamine binds to, and activates, H 1 receptors, which results in the further release of pro-inflammatory cytokines, such as interleukins, from basophils and mast cells. These downstream effects of histamine binding are responsible for a wide variety of allergic symptoms, such as pruritu...

• Afrikaans • العربية • تۆرکجه • Cymraeg • Deutsch • Ελληνικά • Español • Euskara • فارسی • Français • Հայերեն • Bahasa Indonesia • Italiano • Nederlands • 日本語 • ଓଡ଼ିଆ • Polski • Português • Română • Русский • Slovenščina • Српски / srpski • Srpskohrvatski / српскохрватски • Suomi • Svenska • ไทย • Türkçe • Українська • Tiếng Việt • 中文 Key:ZQDWXGKKHFNSQK-UHFFFAOYSA-N Y Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an Common side effects include sleepiness, headache, and a It was first million prescriptions. Medical uses [ ] Hydroxyzine is used in the treatment of A Hydroxyzine can also be used for the treatment of [ medical citation needed] These have also been confirmed in both recent and past studies to have no adverse effects on the liver, blood, nervous system, or urinary tract. [ bettersourceneeded] Use of hydroxyzine for Hydroxyzine is used as a non- [ bettersourceneeded] and for the treatment of Doses of hydroxyzine hydrochloride used for sleep range from 25 to 100mg. Hydroxyzine has been used experimentally for the treatment of Gabasync [ ] In November 2011, the results of a double-blind, placebo-controlled study (financed by Hythiam and carried out at Contraindications [ ] The administration of hydroxyzine in large amounts by ingestion or intramuscular administration during the onset of pregnancy can cause [ bettersourceneeded] In humans, a significant dose has not yet been established in studies and, by default, the Other contraindi...

• • • • Hydroxyzine HCL is used to decrease activity in the central nervous system, and can also be used as an antihistamine to reduce allergic reactions and similar symptoms. Given the wide variety of uses, it is difficult to determine how this medication should be administered, so you will need to follow the instructions set by your doctor. Do not make any changes to your prescription before speaking to your doctor and receiving permission to do so. You will also need to talk with your doctor about how to alter other prescriptions you may be using as these can cause a negative reaction in the body if paired incorrectly. Indications and Usage Hydroxyzine is sold under the brand names Atarax or Vistaril. Itis used as an antihistamine to help reduce the occurrence of sneezing or runny nose. Unlike some antihistamines you can use this drugto treat allergic reactions on the skin, such as hives or contact dermatitis. In some cases, this medication is also used in conjunction with other substances as an anesthesia or to control nausea or vomiting. Hydroxyzine is available in tablet and liquid form. Dosage will vary based on the nature of your symptoms and the condition of the patient. Do not take more of your medication than prescribed as this can lead to severe side effects. If you are taking a tablet form of this drug, take your dose with a full glass of water. Those using the liquid form of this medication should use the dose measuring spoon provided rather than a utensil fr...

Hydroxyzine (Vistaril)* is a • treat • treat itching related to certain conditions, such as • help produce sedation (a state of relaxation and sleepiness) before or after Hydroxyzine comes as an oral tablet and oral capsule. Hydroxyzine also comes in an oral syrup and an injectable form, though this article does not cover them. For more information about these forms, talk with your doctor. Hydroxyzine may be used as a short-term or long-term treatment. As with other drugs, hydroxyzine can cause side effects. Read on to learn about potential common, mild, and serious side effects. For a general overview of hydroxyzine, including details about its uses, refer to * Hydroxyzine capsules are available as the brand-name drug Vistaril. In the past, hydroxyzine tablets were available as the brand-name drug Atarax. However, Atarax is no longer available. Hydroxyzine can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. These are just a few of the more common side effects reported by people who took hydroxyzine in clinical trials of • drowsiness • headache* • * For more information about this side effect, see “Hydroxyzine: Side effect specifics” below. Mild side effects can occur with hydroxyzine use. This list doesn’t include all possible mild side effects of the drug....

Usual Adult Dose for: • • • • • • Usual Pediatric Dose for: • • • • • • Additional dosage information: • • • • • Usual Adult Dose for Anxiety Oral: 50 to 100 mg orally 4 times a day Parenteral: 50 to 100 mg IM immediately, then every 4 to 6 hours as needed Comments: • Use should be periodically reassessed. • Treatment for longer than 4 months have not been assessed in clinical studies. Uses: Oral: • As an adjunct in organic disease states in which anxiety is manifested • Symptomatic relief of anxiety and tension associated with psychoneurosis Parenteral: • Adjunctive treatment in alcoholism • Allay associated anxiety and apprehension attendant to certain types of heart disease • Alleviating anxiety and tension in acute emotional problems or in the preparation for dental procedures • As pre-/postoperative and pre-/postpartum adjunctive medication to allay anxiety • Management of anxiety associated with allergic conditions with strong emotional overlay (e.g., asthma, chronic urticaria, pruritus) • Management of anxiety associated with organic disturbances • Treatment of patients who are acutely/chronically alcoholic with anxiety withdrawal symptoms or delirium tremens • Treatment of patients who are acutely disturbed or hysterical Usual Adult Dose for Atopic Dermatitis Oral: 25 mg orally 3 to 4 times a day Use: Management of pruritus due to histamine-mediated pruritus and allergic conditions (e.g., atopic/contact dermatoses, chronic urticaria) Usual Adult Dose for Pruritus O...

Check with your doctor immediately if any of the following side effects occur: Incidence not known • Chest pain, discomfort, or tightness • cough • difficulty with swallowing • dizziness • fainting • fast heartbeat • hives, itching, or skin rash • irregular or slow heart rate • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue • trouble breathing • unusual tiredness or weakness Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose • Decreased awareness or responsiveness • drowsiness • nausea • seizures • severe sleepiness • vomiting Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Rare • Shakiness in the legs, arms, hands, or feet • trembling or shaking of the hands or feet Incidence not known • Dry mouth • headache • seeing, hearing, or feeling things that are not there Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.