Istavel 100

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Istavel 50 mg Tablet is an antidiabetic medicine. It is used alone or in combination with other medicines to treat type II diabetes in adults (abnormal increase in the blood sugar levels when your body cannot use the insulin it makes effectively to move sugar from the blood into the cells). It works by increasing the production of a hormone known as insulin, which helps in decreasing the excessive sugar level in the blood. Istavel 50 mg Tablet shows common side effects such as sore throat, stuffy nose, low blood sugar level, or headache. If these symptoms persist or worsen, consult your doctor for further assistance. Istavel 50 mg Tablet can be taken with or without food as directed by the doctor. Take the medicine at the same time daily for ease of remembering. Do not discontinue the medicine without consulting your doctor, as it can worsen your condition. Avoid the consumption of alcohol while taking this medicine as it may affect your blood sugar levels. Istavel 50 mg Tablet is not recommended if you are allergic to it. It should be taken with caution if you have kidney or heart condition, gallstones (hardened deposits that form in the gallbladder), pancreatitis (swelling of the pancreas, an organ vital for digestion and to control blood sugar levels), or a high triglyceride level (a type of fat). Istavel 50 mg Tablet is not recommended for use in children under 18 years of age as there is a lack of safety and efficacy data. Consult your doctor before taking this medici...

INTRODUCTION ISTAVEL D 5/100 TABLET is a combination of Dapagliflozin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to treat type II diabetes mellitus which is inadequately controlled on metformin monotherapy. Type 2 diabetes is a condition in which your body does not make enough insulin and the insulin that is produced does not work as well as it should. This results in sugar (glucose) build-up in the blood and thus high blood sugar levels. ISTAVEL D 5/100 TABLET is not recommended for use in patients having severe kidney problems or those on dialysis. Before taking ISTAVEL D 5/100 TABLET, inform your doctor if you have inflammation of the pancreas, gallstones, alcohol dependence, or very high levels of triglycerides (a form of fat) in the blood or any heart, kidney or liver problems. ISTAVEL D 5/100 TABLET should be used in pregnant women only if considered clearly necessary. ISTAVEL D 5/100 TABLET should be used with caution in breastfeeding women. Safety and effectiveness of ISTAVEL D 5/100 TABLET in children and adolescents (under 18 years of age) have not been established. It is important to stay on the diet and exercise recommended by your doctor while taking ISTAVEL D 5/100 TABLET as it can help your body use its blood sugar better. The most common side effects of taking ISTAVEL D 5/100 TABLET are nausea, headache, flatulence and constipation. Consult your doctor if any of the side effects worsen or persist...

TabletWise.com website users have reported 1 week and 1 day as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Istavel Tablet. • In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Before taking this medicine You should not use sitagliptin if you are allergic to it, or if you have Tell your doctor if you have ever had: • kidney disease (or if you are on dialysis); • heart problems; • • • • Follow your doctor's instructions about using sitagliptin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. Your name may need to be listed on a sitagliptin pregnancy registry when you start using this medicine. It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. Sitagliptin is not approved for use by anyone younger than 18 years old. How should I take sitagliptin? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take this medicine with or without food. Follow your doctor's instructions. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. You may have (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat Your doctor may prescribe a Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination. Blood sugar levels can be affected by Ask your doctor before changing your dose or medication schedule. Si...

Istavel Tablet The DPP-4 inhibitors are a class of agents that act as incretin enhancers. By inhibiting the DPP-4 enzyme, Istavel increases the levels of two known active incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). The incretins are part of an endogenous system involved in the physiologic regulation of glucose homeostasis. When blood glucose concentrations are normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells. GLP-1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production. This mechanism is unlike the mechanism seen with sulfonylureas; sulfonylureas cause insulin release even when glucose levels are low, which can lead to sulfonylurea-induced hypoglycemia in patients with type ll diabetes and in normal subjects. Istavel demonstrates high selectivity for DPP-4 and does not inhibit closely-related enzymes DPP-8 or DPP-9 at therapeutic concentrations. Istavel inhibits DPP-4 which leads to increased levels of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide(GIP), decreased levels of glucagon, and a stronger insulin response to glucose. Uses Monotherapy: Istavel is used for an adjunct to diet and exercise to improve glycemic control in patients with type ll diabetes mellitus. Combination with Metformin: Istavel is used for patients with type 2 diabetes mellitus to improve glycemic contro...