Itraconazole capsules 200 mg

Itraconazole (Monograph) Brand name: Drug class: Azoles VA class: AM700 Chemical name: 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-l]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one CAS number: 84625-61-6 • • • • • • • Warning • Itraconazole capsules should not be used for treatment of onychomycosis in patients with evidence of ventricular dysfunction, including CHF or history of CHF. • Discontinue itraconazole if signs or symptoms of CHF occur. IV itraconazole (no longer commercially available in the US) caused negative inotropic effects in healthy individuals and in dogs. • Concomitant use with cisapride (currently commercially available in the US only under a limited-access protocol), pimozide, quinidine, dofetilide, or levomethadyl (no longer commercially available in the US) is contraindicated. Itraconazole is a potent inhibitor of CYP3A4 isoenzymes and may increase plasma concentrations of drugs metabolized by CYP3A4. Serious cardiovascular events, including QT prolongation, torsades de pointes, ventricular tachycardia, cardiac arrest, and/or sudden death have occurred in patients using cisapride, pimozide, levomethadyl, or quinidine concomitantly with itraconazole and/or other CYP3A4 inhibitors. (See Interactions.) Introduction Antifungal; azole (triazole derivative). Related/similar drugs Uses for Itraconazole Aspergillosis Treatment of invasive aspergillosis. Considered an alternativ...

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. Itraconazole capsules and tablets should be taken with a full meal. The oral liquid is best taken on an empty stomach. Take the tablets at the same time each day. Measure the oral liquid with a marked measuring spoon or medicine cup. If you have thrush in the mouth or throat, place 10 milliliters (mL) of the liquid in your mouth, swish for several seconds, then swallow. Repeat these steps if your total dose is more than 10 mL. If you are using antacids (eg, Maalox®, Mylanta®, Pepcid® Complete, Rolaids®, or Tums®) or other stomach medicine (eg, H2 blocker, proton pump inhibitor), take them at least 2 hours before or 2 hours after using itraconazole. You may also take itraconazole with an acidic beverage (eg, non-diet cola) if you are taking it with an antacid. Use only the brand and the dosage form of this medicine that your doctor prescribed. Different brands and dosage forms may not work the same way. Sporanox® oral liquid works differently than itraconazole Sporanox® capsules, even at the same dose (number of milligrams). Do not switch from the capsules to the oral liquid unless your doctor tells you to. Dosing The dose of this medicine will be different f...