Ketoconazole

• العربية • تۆرکجه • Cymraeg • Deutsch • Ελληνικά • Español • فارسی • Français • Galego • 한국어 • Հայերեն • Bahasa Indonesia • Italiano • Lingua Franca Nova • Magyar • Македонски • Nederlands • 日本語 • ଓଡ଼ିଆ • Polski • Português • Română • Русский • Slovenščina • Српски / srpski • Srpskohrvatski / српскохрватски • Suomi • ไทย • Türkçe • Українська • Tiếng Việt • 中文 Medical uses [ ] Topical antifungal [ ] Topically administered ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as Systemic antifungal [ ] Ketoconazole has activity against many kinds of fungi that may cause human disease, such as Ketoconazole is used orally in dosages of 200 to 400mg per day in the treatment of superficial and deep fungal infections. Off-label uses [ ] Hair loss [ ] See also: The side effects of ketoconazole are sometimes harnessed in the treatment of non-fungal conditions. While ketoconazole blocks the synthesis of the sterol Ketoconazole has been used to prevent the Contraindications [ ] Oral ketoconazole has various Side effects [ ] Gastrointestinal [ ] Vomiting, diarrhea, nausea, constipation, abdominal pain, upper abdominal pain, dry mouth, Endocrine [ ] The drug may cause Liver [ ] In July 2013, the Hypersensitivity [ ] Topical formulations [ ] The topical formulations have not been associated with liver damage, adrenal problems, or drug interactions. These formulations include creams, shampoos, foams, and gels applied to the skin, unlike the ket...

Ketoconazole is an It treats different types of fungal infections including: • • jock itch, an infection in the groin area • sweat rash (intertrigo), a rash that usually appears in folds of skin • • Ketoconazole is available as a cream or shampoo. You can buy most ketoconazole creams and shampoos in pharmacies and supermarkets, or get them on prescription. For treating pityriasis versicolor, you will need a prescription. Ketoconazole also comes as tablets but these usually only treat a rare condition called • Ketoconazole usually works within 2 to 3 weeks for most fungal infections, but it can take 6 weeks for athlete's foot to get better. • It works by killing the yeasts (fungi) that cause the infections. • The most common side effects of the cream and shampoo are irritated or red skin. • For most infections, you'll usually use the cream once or twice a day and the shampoo once or twice a week. • Some people use ketoconazole shampoo every 1 to 2 weeks to help stop dandruff coming back. 3. Who can and cannot use ketoconazole Ketoconazole creams and shampoos can be used by most adults and children aged 12 years and over. Ketoconazole is not suitable for everyone. To make sure it's safe for you, talk to your doctor or pharmacist before using it if you have ever had an allergic reaction to ketoconazole or any other medicine. 4. How and when to use ketoconazole Always follow the instructions that come with your medicine, or your doctor's advice. How long you use ketoconazole f...

• Your doctor has prescribed Ketoconazole to cure your infection and improve symptoms. • Do not skip any doses and finish the full course of treatment even if you feel better. • Take it with food, preferably at the same time every day. • Do not take indigestion remedies (antacids) within two hours of taking Ketoconazole. • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. •

What is ketoconazole? Ketoconazole is an imidazole medicine used to treat infections. Ketoconazole binds to the fungal p450 enzymes and stops the cells making ergosterol, the main component of the cell wall. In New Zealand, it is available as shampoo and cream. Ketoconazole is effective against a broad spectrum of fungi including: • • Yeasts such as Ketoconazole 2% Cream (Nizoral Cream®) daily and 2% Shampoo (Nizoral®, Sebizole®) twice weekly are used for seborrhoeic dermatitis, a common scaly rash affecting scalp and face. They are subsidised on prescription, but can also be obtained over the counter at a chemist. Topical ketoconazole is safe. Oral ketoconazole Oral ketoconazole was discontinued in New Zealand 1 December 2013. As it may still be available elsewhere, information about the product is included below. Ketoconazole reaches the surface of the skin through normal blood circulation, sweat and sebum (skin oils). Very high concentrations of the drug develop within the skin, so it is effective in treating superficial fungal infections. The oral dose of ketoconazole in adults is 200 to 400 mg daily, taken for two to eight weeks (a single dose may be effective for pityriasis versicolor). Nail infections are treated for up to twelve months. The dose in children is usually 50 mg per day for those weighing less than 20 kg and 100mg daily for those 20-40 kg. The oral medication is somewhat better absorbed when it is taken with a fatty meal or acidic drink (e.g. orange jui...

What is this medication? KETOCONAZOLE (kee toe KON na zole) treats fungal or yeast infections of the skin. It may also be used to treat seborrheic dermatitis, a condition that causes dry, flaky, and itchy skin. It belongs to a group of medications called antifungals. It will not treat infections caused by bacteria or viruses. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Kuric, Nizoral What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • Large areas of burned or damaged skin • An unusual or allergic reaction to ketoconazole, other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? This medication is for external use only. Do not take by mouth. Wash your hands before and after use. If you are treating your hands, only wash your hands before use. Do not use on healthy skin or over large areas of skin. Do not get this medication in your eyes. If you do, rinse it out with plenty of cool tap water. Use it as directed on the label at the same time every day. Do not use it more often than directed or for a longer time period than prescribed by your care team. Keep taking it unless your care team tells you to stop. Apply a thin film to the affected area and rub gently. Do not bandage or wrap the skin being treated unless directed to do so by your ca...

When you have a headache or a cold, it’s easy to go to any drugstore (or even some convenience stores) and buy medicine to treat your symptoms. You won’t have a problem getting Tylenol, Imodium, Vicks, or Advil, and the cashier wouldn’t bat an eye over whether you buy one capsule or the entire box. In other cases, however, your symptoms are not just everyday symptoms. Whether it’s extreme pain that regular painkillers can’t handle or a thyroid condition that’s making you palpitate, these are symptoms that cannot be explained as an everyday sickness and require more potent medicine you won’t find in any convenience store. But when you get to the drugstore, the pharmacists can refuse to give you medicine without a doctor’s prescription. And they’re legally capable of doing so because these special drugs require a medical prescription. Today, we’ll help you understand the differences between prescription and over-the-counter medicines. We’ll explain how prescriptions came to be and how they protect the patient from overdosing or misusing antibiotics and potent active ingredients. To show this, we’ll be using Ketoconazole and its various product forms as an example. Table of Contents • • • • • • • • • • • • • • • • • • Medical Prescriptions Originally, medical prescriptions were not a legal and medical requirement and was only a piece of paper where doctors wrote on the spot for patients with specific ailments. Before the 1950s, pharmacists had to compound medicine’s raw ingre...

Description and Brand Names Drug information provided by: US Brand Name • Extina • Ketodan Kit • Kuric • Nizoral • Nizoral A-D • Xolegel Canadian Brand Name • Ketoderm Descriptions Ketoconazole is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth. Ketoconazole cream is used to treat: • Athlete's foot (tinea pedis; ringworm of the foot); • Ringworm of the body (tinea corporis); • Ringworm of the groin (tinea cruris; jock itch); • Seborrheic dermatitis; • "Sun fungus" (tinea versicolor; pityriasis versicolor); and • Yeast infection of the skin (cutaneous candidiasis). Ketoconazole foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp). Ketoconazole 1% shampoo is used to treat dandruff. Ketoconazole 2% shampoo is used to treat "sun fungus" (tinea versicolor; pityriasis versicolor). This medicine may also be used for other fungus infections of the skin as determined by your doctor. Most forms of this medicine are available only with your doctor's prescription. Some forms are available without a prescription. However, your doctor may have special instructions on the proper use for your medical condition. This product is available in the following dosage forms: • Shampoo • Cream • Foam • Gel/Jelly

Ketoconazole (Ketoconazole HRA™), an imidazole derivative, is a useful treatment option in the management of endogenous Cushing’s syndrome in adults and adolescents > 12 years of age, based on evidence from more than three decades of use of the drug in clinical practice. Originally developed as an antifungal agent, ketoconazole is a potent steroidogenesis inhibitor. Approximately 60% (range, 45–88% across key studies) of patients with Cushing’s syndrome who are treated with ketoconazole achieve control of hypercortisolism, with efficacy demonstrated in all aetiologies of the disease. Furthermore, reductions in cortisol levels in patients treated with ketoconazole are associated with improvements in clinical and biochemical features of Cushing’s syndrome and common comorbidities. Hepatotoxicity, the main safety concern with ketoconazole, can be managed effectively with careful monitoring of hepatic enzymes, with hepatic enzyme abnormalities generally being mild to moderate, asymptomatic and reversible upon dose reduction or drug withdrawal. Indicated in the EU for the treatment of endogenous Cushing’s syndrome in adults and adolescents > 12 years of age Normalisation of urinary free cortisol levels achieved in ~ 60% (range, 45–88% across key studies) of treated patients, with further patients achieving partial control Risk of hepatotoxicity can be managed effectively with careful monitoring and dose reduction or drug withdrawal if required Other potential adverse events inc...