Levocetirizine hydrochloride & montelukast sodium syrup

Xyzal Generic Name Levocetirizine DrugBank Accession Number DB06282 Background Levocetirizine is a selective histamine H 1 antagonist used to treat a variety of allergic symptoms. 1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995. Type Small Molecule Groups Approved Structure inhibitor Humans Absorption Following a 5mg oral dose of levocetirizine, a C max of 0.27±0.04µg/mL with a T max of 0.75±0.50h. max by 1.25 hours and lowers C max by 36%. Volume of distribution The volume of distribution of levocetirizine is 0.33±0.02L/kg. Protein binding Plasma protein binding of levocetirizine was on average 96.1% 1 hour post dose and 91.9% 6 hours post dose. Metabolism Levocetirizine is poorly metabolized with 85.8% of an oral dose being excreted as the unchanged drug. Hover over products below to view reaction partners • Levocetirizine • Route of elimination 168 hours post dose an average of 85.4% of a radiolabeled dose was recovered with an average of 80.8% in the urine and 9.5% in the feces. Half-life The average half life of levocetirizine is 7.05±1.54 hours. Clearance The average clearance of levocetirizine is 0.57±0.18mL/min/kg. Adverse Effects The risk or severity of CNS depression can be increased when Levocetirizine is combined with 1,2-Benzodiazepine. Abacavir may decrease the excretion rate of Levocetirizine which could result in a higher serum level. The serum concentration of Levocetirizine can be increased when it is combined with Abametapir. ...

Although both are considered nonsedating antihistamines, both Xyzal and Zyrtec have drowsiness as a potential side effect. Zyrtec is considered a second-generation antihistamine, and Xyzal is a third-generation antihistamine. These medications are classified by how likely they are to reach the brain and cause drowsiness. First-generation antihistamines, such as Second generation are less likely to reach the brain or be sedating, and third-generation antihistamines are the least likely. However, they all still have the potential to make you feel tired. As you should with every medication, confer with your doctor before taking Xyzal or Zyrtec. Some important subjects to discuss with your doctor include: • Allergies. Tell your doctor about any medication allergies, including those to levocetirizine (Xyzal) and cetirizine (Zyrtec). • Medications. Talk to your doctor about other prescription and OTC medications or supplements you currently use — especially • Medical history. Tell your doctor if you have a history of kidney disease or liver disease. • Pregnancy. Are you pregnant or do you plan to become pregnant? There are no well-controlled studies of using Xyzal or Zyrtec during pregnancy, so discuss the pros and cons with your doctor. • Breastfeeding. You shouldn’t breastfeed when taking Xyzal or Zyrtec. • Alcohol consumption. Alcoholic beverages can add to the drowsiness caused by Xyzal or Zyrtec. Xyzal and Zyrtec are both antihistamines. • • • itching • They can also addres...

What Are Possible Side Effects of Xyzal? Common • drowsiness, • • weakness, • • • • • • vomiting, • • • • weight gain Tell your • • nosebleeds (especially • pain or fullness in your • hearing problems, • • agitation, • aggression, • hallucinations, • numbness or tingling around your • yellowing of your • painful or • dark-colored • foul-smelling stools, • • • loss of appetite What Are Possible Side Effects of Allegra? Common side effects of Allegra include: • • diarrhea, • upset stomach, • • sleepiness, • drowsiness, • • • Contact your doctor if you have serious but less common side effects of Allegra including • allergic reactions, • fever, • • body aches, • cough, or • other How Should Allegra Be Taken? Do not use if you have ever had an Ask a doctor before use if you have When using this product • do not take more than directed • do not take at the same time as • do not take with fruit juices Stop use and ask a doctor if an allergic reaction to this product occurs. Seek medical help right away. If pregnant or breast-feeding, ask a Keep out of reach of children. All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA). Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph. Drug information found in the drug comparisons published on Rx...

Key:ZKLPARSLTMPFCP-OAQYLSRUSA-N Y N Y Levocetirizine, sold under the brand name Xyzal among others, is a second-generation Common side effects include sleepiness, dry mouth, cough, vomiting, and diarrhea. 1-receptors. Levocetirizine was approved for medical use in the United States in 2007. million prescriptions. Medical uses [ ] Levocetirizine is used for allergic rhinitis. Side effects [ ] Levocetirizine is referred to as a non-sedating antihistamine as it does not enter the brain in significant amounts and is therefore unlikely to cause drowsiness. Cardiac safety with repolarization may be better than some other antihistamines, as levocetirizine does not significantly Pharmacology [ ] Levocetirizine is an R)-(-)-cetirizine, is essentially a S)-counterpart, the Chemistry [ ] Chemically, levocetirizine is the active levorotary l-enantiomer of cetirizine. It is a member of the History [ ] Levocetirizine was first launched in 2001 by the Belgian pharmaceutical company Union Chimique Belge). Society and culture [ ] Availability [ ] On 31 January 2017, the Brand names [ ] Preparations of levocetirizine are sold under the following brand names: • Xyzal ˈ z aɪ ˌ z ɑː l/ (sometimes spelled Xyzall) in Australia, Austria, Bulgaria, Croatia, Cyprus, Czech Republic, Finland, France, Hungary, India, Ireland (also Rinozal), Italy, Japan, Lithuania, Netherlands, Poland, Portugal, Romania, Taiwan, Thailand, Turkey, The Philippines, Serbia, Singapore, Slovakia, Slovenia, South Africa, Sp...

Description and Brand Names Drug information provided by: US Brand Name • Xyzal Descriptions Levocetirizine is used to relieve the symptoms of hay fever and hives of the skin. It is an antihistamine that works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can also close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Histamine can also cause some persons to have hives, with severe itching of the skin.