Mbasso

asm-dom A minimal WebAssembly virtual DOM to build C++ SPA (Single page applications) Table of Contents • • • • • • • • • Motivation asm-dom is a minimal WebAssembly virtual DOM to build C++ SPA (Single page applications). You can write an entire SPA in C++ and compile it to WebAssembly (or asmjs as fallback) using aims to execute at native speed by taking advantage of common hardware capabilities, also, you can use your C/C++ code without any change, you haven't to create a binding layer to use it (as we have to do if we want to use a C++ lib from JS). Basically we are creating an app in C++ that call javascript if needed instead of the opposite. You can write only once in C++ and share as much code as possible with desktop/mobile apps and web site. If you want to learn more about performance, please see How can I structure my application with asm-dom? asm-dom is a low-level virtual DOM library. It is unopinionated with regards to how you should structure your application. How did you come up with the concept of asm-dom? At the beginning asm-dom is born from the idea to test the powerful of WebAssembly in a common use case that is not gaming, VR, AR or Image / video editing. Unfortunately, at the moment, 🦄, so, asm-dom isn't totally developed in wasm. All interactions with the DOM are written in Javascript. This is a big disadvantage because of the overhead of the binding between JS and WASM, in the future asm-dom will be even more powerful, anyway results are satisfying....

Michele A. Basso Pronouns: She/Her/Hers Phone: Email: Department: Professor, Biological Structure, Physiology and Biophysics Director, WaNPRC Neuroscience Focus Groups: Behavioral Neuroscience, Disorders of the Nervous System, Motor Systems and Sensorimotor Integration, Neural Circuits Research: The work performed in the Basso laboratory is aimed at unraveling the neuronal circuits of decision-making in health and disease. Dr. Basso’s work spans multiple species and employs multiple technologies designed to understand how memory and sensory information are combined to give rise to our decisions and choices of action.

CONTACT Email : mbasso @uw.edu Phone : (206) 543-0440 BASSO LAB Website PROFESSOR Director of the Washington National Primate Research Center (WaNPRC) Research Focus: Systems Neuroscience, Neural Circuits, and Computational Neuroscience RESEARCH Dr. Basso studied Neuroscience at Stony Brook University in NY and was a post-doctoral fellow at the National Eye Institute, NIH. After serving as a faculty member at the University of Wisconsin Madison, she moved to UCLA and was then recruited to the University of Washington to serve as Director of the Washington National Primate Research Center (WaNPRC). The work performed in Dr. Basso’s laboratory is aimed at unravelling the neuronal circuits of decision-making in health and disease. Her work spans multiple species and employs multiple technologies designed to understand how memory and sensory information are combined to give rise to our decisions and choices of action. RECENT PUBLICATIONS Villalobos, CA, Basso MA. Cell Reports. 2022 39(3): 1-14. Milham M et al. Neuron. 2022 110(1): 16-20. Thakur VN, Basso MA, Ditterich J, Knowlton BJ. Scientific Report. 2021 11(1): 1-12. Jun EJ, Bautista AR, Nunez MD, Allen, D.C., Tak JH, Alvarez E, Basso MA. Nature Neuroscience. 2021 24(8): 1121-1131. Basso MA, Bickford ME, Cang J. Neuron. 2021 109(6): 918-937. LAB MEMBERS Vaibhav Thakur Krystyna Wieczerzak

Michele A. Basso Professor Biological Structure and Physiology and Biophysics School of Medicine What is your Research Focus? My research program seeks to answer some of the most pressing questions in neuroscience and I incorporate a variety of experimental approaches, bridging gaps between cellular and systems level neuroscience. We know very little about how the activity of populations of neurons and the circuits they create give rise to higher mental function, yet answers to circuit-based questions I believe, will reveal the fundamental mechanisms underlying neurological and neuropsychiatric diseases ranging from Parkinson’s disease and dystonia, to addiction, autism, depression and schizophrenia. The primary focus of my lab emphasizes behavioral, electrophysiological and computational techniques in monkeys. We also perform experiments using the in vitro rodent model, biophysical tools such as patch-clamp recording, and we make use of advances in molecular biology and genetics using transgenic mice combined with optogenetics to uncover cellular and circuit mechanisms of higher mental function. In the lab, we also extend the principles learned from fundamental science to translational research with patients. These efforts are leading to new ways of thinking about symptoms seen in patients with Parkinson’s disease. Our work represents an important step forward in understanding the neurobiology of Parkinson’s disease and may help fill unmet clinical needs by providing clue...