Nimesulide and paracetamol tablet uses

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. Chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. Tablet/Suspension: Adults: Treatment of a variety of painful inflammat...

Identification Summary Nimesulide is a cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Generic Name Nimesulide DrugBank Accession Number DB04743 Background Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries. Type Small Molecule Groups Approved, Investigational, Withdrawn Structure Learn more Pharmacodynamics Food, gender and advanced age have negligible effects on nimesulide pharmacokinetics. Mechanism of action The therapeutic effects of Nimesulide are the result of its complete mode of action which targets a number of key mediators of the inflammatory process such as: COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine. Target Actions Organism A inhibitor Humans U Not Available Humans U Not Available Humans Absorption Rapidly absorbed following oral administration. Volume of distribution Not Available Protein binding >97.5% Metabolism Hepatic. Extensive biotransformation, mainly to 4-hydroxynimesulide (which also appears to be biologically active). Route of elimination Renal (50%), fecal (29%) Half-life 1.8–4.7 hours Clearance Not Available Adverse Effects...

Nimesulide is used to treat pain, inflammation and fever. It is classified as a cyclooxygenase 2 inhibitor (COX-2) selective non-steroidal anti-inflammatory drug (NSAID). Nimesulide is not approved for use in the U.S. due to concerns about the risk of serious liver toxicity. Nimesulide has been withdrawn from the market in many countries due to these safety concerns. In countries where nimesulide is approved for human use, it may be used to treat conditions such as Is nimesulide approved in the U.S? No. In the U.S. the only approved COX-2 inhibitor is Nimesulide dosage forms include capsules, tablets, topical gels, topical spray, suppositories and powder or granules for oral suspension. It has been found in combination with capsaicin, lidocaine, or thiocolchicoside for topical use as an anti-inflammatory. Is nimesulide approved in Europe? Yes. According to The European Medicines Agency (EMA), a safety review found the benefits of systemic nimesulide continue to outweigh its risks but that its use should be restricted to the treatment of acute pain and primary dysmenorrhea. However, length of use was restricted to two weeks and as a second line treatment. EMA guidelines state it should not be used for the treatment of painful osteoarthritis, a chronic, long-term condition, due to higher risk for liver toxicity. How does nimesulide work? Nimesulide works by specifically targeting and blocking COX-2 enzymes, which are mediators of inflammation and pain. By targeting COX-2 enz...

Nemol Plus Tablet is an anti-inflammatory pain killer, containing Nimesulide and Paracetamol as active ingredient. It can be used to treat acute pain, pain related to menstrual cramps, backache, post-operative pains, osteoarthritis and fever. As this medicine is a combination of two drugs belonging to the same class, which is NSAID (Non-steroidal anti-inflammatory drugs). This medication functions by blocking the cyclooxygenases which actually produces pain signals in our body. This drug works by exerting pain relieving activities. Cyclooxygenases and Prostaglandin are the reasons for the occurrence of inflammation, swelling of joints and other acute pains. Cyclooxygenase is a type of enzyme which produces compounds known as Prostaglandin. The existence of Prostaglandin in your body creates inflammation in joints, swelling and pain. This medication is a cyclooxygenase inhibitor, so it effectively reduces these symptoms. If this medicine is given in high dosage, these drugs can also be used in treating inflammation in the body. But it is not good to use the drug for a prolonged period due to its harmful side effects. It is always advisable to finish the passage within 15 days. • How long is the duration of effect? On average, the effects of the medication can last for 24 hours. • What is the onset of action? The onset of the effects is immediate. • Are there any pregnancy warnings? Pregnant women must consult doctor before using this medication. • Is it habit forming? There...

Nims 100mg/15mg Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat. Nims 100mg/15mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor. The most common side effects of this medicine include nausea, vomiting, diarrhea, and increased liver enzymes. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects. Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness. Nims 100mg/15mg Tablet is a combination of two medicines that belon...