Nitroglycerin

Highlights for nitroglycerin • Nitroglycerin sublingual tablet is available as both a generic and a brand-name drug. Brand name: Nitrostat. • A sublingual tablet is a tablet that you dissolve under your tongue or inside your cheek. Nitroglycerin also comes as a spray, aerosol solution, transdermal patch, and ointment. In addition, it comes in an injectable form that’s only given by a healthcare professional. • Nitroglycerin sublingual tablet is used to stop or prevent angina (chest pain). Nitroglycerin sublingual tablet is a prescription drug that’s available as the brand-name drug Nitrostat. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Nitroglycerin also comes as a spray, aerosol solution, transdermal patch, and ointment. It also comes in an injectable form that’s only given by a healthcare professional. To take the sublingual tablet, you place it under your tongue or inside your cheek and let it dissolve. Why it’s used Nitroglycerin is used to treat How it works Nitroglycerin belongs to a class of drugs called vasodilators. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Nitroglycerin works by relaxing the smooth muscle and blood vessels in your body. This increases the amount of blood and oxygen that reaches your heart. In turn, your heart doesn’t w...

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Nitroglycerin (oral/sublingual) Generic name: nitroglycerin (oral/sublingual) [ NYE-troe-GLI-ser-in] Brand names: Dosage forms: oral capsule, extended release (2.5 mg; 6.5 mg; 9 mg), sublingual powder (400 mcg), sublingual spray (0.4 mg), sublingual tablet (0.3 mg; 0.4 mg; 0.6 mg) Drug classes: • • • • • • • Before taking this medicine You may not be able to use nitroglycerin if you have: • severe • increased pressure inside the skull; • circulation problems or • if you also take Do not use Tell your doctor if you have ever had: • an allergic reaction to nitroglycerin; • a • Tell your doctor if you are pregnant or breastfeeding. Not approved for use by anyone younger than 18 years old. How should I take nitroglycerin? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Try to rest or stay seated when you take nitroglycerin (may cause Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Use nitroglycerin at the first sign of chest pain. Use another dose every 5 minutes as needed, up to a total of 3 doses. Get emergency medical help if you still have chest pain after using a total of 3 doses in 15 minutes, or if your chest pain seems unusual. You may use nitroglycerin sublingual within 5 to 10 minutes before an activity that might cause chest pain. This medicine can affect the results of...

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions. Nitroglycerin is available as two types of products that are used for different reasons. The extended-release capsules are used every day on a specific schedule to prevent angina attacks. The oral spray, sublingual powder, and sublingual tablets work quickly to stop an angina attack that has already started or they can be used to prevent angina if you plan to exercise or expect a stressful event. When you begin to feel an attack of angina starting (chest pains, tightness or squeezing in the chest), sit down. Then place a sublingual powder or tablet in your mouth or under your tongue. If you use the oral spray, you should spray it on or under the tongue. You may become dizzy, lightheaded, or faint soon after using a tablet or spray, so it is safer to sit rather than stand while the medicine is working. If you become dizzy or faint while sitting, take several deep breaths and bend forward with your head between your knees. Remain calm and you should feel better in a few minutes. If you are taking the nitroglycerin sublingual powder: Empty the contents of a packet under your tongue. Close your mouth and breathe normally. Allow powder to dissolve without swallowing. Do not rinse or spit for 5 minutes after taking this medicine. Do not take more than 3 packets in 15 minutes. If you still have pain after you take a total of 3...

When something restricts blood flow to the heart muscle, a person may experience intense chest pain that doctors call angina. People can use the drug nitroglycerin to relieve this pain. Most often, the reason for this decrease in blood flow is plaque formation and the narrowing of the arteries supplying blood to the heart. Nitroglycerin helps open up the blood vessels and allows blood to flow. People can also use nitroglycerin to treat anal fissures. This article provides an overview of nitroglycerin, including its uses, how it works, possible side effects, interactions, and warnings. Nitroglycerin is a medication that treats The body breaks nitroglycerin down into nitric oxide. Nitric oxide causes the smooth muscle within the blood vessels to relax. This allows the arteries and veins to open up, allowing more blood to flow through. Healthcare professionals call this action vasodilation. During an angina attack, a person will experience intense chest pain. Nitroglycerin will start working within Different forms of the medication start working at different time periods, depending on their formulation. For example: • sublingual tablet: 1–3 minutes • translingual spray: 1–3 minutes • extended-release tablet: 60 minutes • topical ointment: 15–30 minutes • transdermal patch: 30 minutes • intravenous: immediately The medication’s maximal effect also depends on its formation. For example: • sublingual tablet: 7 minutes • translingual spray: 4–15 minutes • extended-release tablet:...

Description and Brand Names Drug information provided by: US Brand Name • Gonitro • Nitrocot • Nitrolingual • NitroMist • Nitroquick • Nitrostat • Nitrotab • Nitro-Time Canadian Brand Name • Gen-Nitro • Nitrolingual Pumpspray Descriptions Nitroglycerin is used to prevent angina (chest pain) caused by coronary artery disease. This medicine is also used to relieve an angina attack that is already occurring. Nitroglycerin belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load. When used regularly on a long-term basis, or just before exercise or a stressful event, this helps prevent angina attacks from occurring. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: • Spray • Tablet • Capsule, Extended Release • Packet

Nitroglycerin is used for the treatment of Angina [ ] GTN is useful in decreasing [ citation needed]It may also be given as a Other uses [ ] Tentative evidence indicates efficacy of glyceryl trinitrate in the treatment of various GTN is also used in the treatment of GTN has been used to decrease pain associated with GTN was once researched for the prevention and treatment of Tolerance [ ] After long-term use for chronic conditions, [ citation needed] and was first described soon after the introduction of GTN in cardiovascular therapy. Studies have shown [ citation needed] that nitrate tolerance is associated with vascular abnormalities which have the potential to worsen patients' prognosis. [ full citation needed] These include endothelial and autonomic dysfunction. [ full citation needed] The mechanisms of nitrate tolerance have been investigated over the last 30 years, and several hypotheses to explain tolerance have been offered, including: • plasma volume expansion • impaired transformation of GTN into NO or related species • counteraction of GTN vasodilation by neurohormonal activation • oxidative stress [ full citation needed] Recent evidence suggests [ weaselwords] that deleterious GTN-induced production of oxygen free radicals might induce a number of abnormalities, include those described above, so that the oxidative stress hypothesis might represent a unifying principle. Adverse events [ ] Glyceryl trinitrate can cause severe GTN also can cause severe hypotension...

Take this Swallow this medication whole. Do not crush or chew the capsules. Doing so can release all of the drug at once and may increase your risk of side effects. Use this medication regularly to get the most benefit from it. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Tell your doctor if this medication stops working well (for example, you have worsening Headache is often a sign that this medication is working. Your doctor may recommend treating To reduce the risk of dizziness and Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before using thi...