Pernicious anemia icd 10

Pernicious anemia Pernicious anemia Classification & external resources D51.0 281.0 DiseasesDB 9870 000569 eMedicine med/1799 D000752 Pernicious anemia (also known as Biermer's anaemia or Addison's anaemia or Addison-Biermer anaemia) is a form of 12 deficiency dependent on impaired absorption of vitamin B 12 in the setting of any cause of 12 deficiency, its proper usage refers to that caused by atrophic gastritis and parietal cell loss only. Contents • 1 Mechanisms & manifestations • 1.1 Pathophysiology • 1.2 Presentation • 2 Causes • 3 Diagnosis • 4 Treatment • 4.1 History • 5 Famous sufferers Mechanisms & manifestations Pathophysiology Vitamin B 12 cannot be produced by the human body, and must therefore be obtained from diet. Normally, dietary vitamin B 12 can only be absorbed by the 12 deficiency and thus megaloblastic anaemia. Presentation Main article: The presentation of pernicious anaemia resembles that of any other form of anaemia, but is often accompanied by the manifestations of vitamin B 12 deficiency (notably neurological abnormalities such as Causes Most commonly, the cause for impaired binding of vitamin B 12 by intrinsic factor is 12). Less frequently, loss of parietal cells may simply be part of a widespread atrophic gastritis of non-autoimmune origin, such as that frequently occurring in elderly people affected with long-standing chronic 12 deficiency other than pernicious anaemia must be considered in the Diagnosis A diagnosis of pernicious anaemia first...

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