Polyethylene glycol

What is this medication? POLYETHYLENE GLYCOL (pol ee ETH i leen; GLYE col) prevents and treats occasional constipation. It works by increasing the amount of water your intestine absorbs. This softens the stool, making it easier to have a bowel movement. It also increases pressure, which prompts the muscles in your intestines to move stool. It belongs to a group of medications called laxatives. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): GaviLax, GIALAX, GlycoLax, Healthylax, MiraLax, Smooth LAX, Vita Health What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • History of blockage in your bowels • Nausea • Phenylketonuria • Stomach or intestine problem • Stomach pain • Sudden change in bowel habit lasting more than 2 weeks • Vomiting • An unusual or allergic reaction to polyethylene glycol (PEG), other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? Take this medication by mouth. Take it as directed on the label. Add the right dose to 4 to 8 ounces or 120 to 240 mL of water, juice, soda, coffee or tea. Do not mix this medication with foods or other liquids. Do not combine with starch-based thickeners (e.g., flour, cornstarch, arrowroot, tapioca, xanthan gum). Mix well. Drink the solution. Do not use it more often than directed. Talk to yo...

What is polyethylene glycol 3350? Polyethylene glycol 3350 is a laxative solution that increases the amount of water in the intestinal tract to stimulate bowel movements. Polyethylene glycol 3350 is used as a laxative to treat occasional Polyethylene glycol 3350 may also be used for purposes not listed in this medication guide. Before taking this medicine You should not use this medicine if you are allergic to polyethylene glycol, or if you have a bowel obstruction or intestinal blockage. If you have any of these conditions, you could have dangerous or life-threatening side effects from polyethylene glycol 3350. People with To make sure this medicine is safe for you, tell your doctor if you have: • • • • kidney disease; or • if you have had a sudden change in bowel habits that has lasted 2 weeks or longer. FDA It is not known whether polyethylene glycol 3350 passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take polyethylene glycol 3350? Follow all directions on your prescription label. Do not use polyethylene glycol 3350 in larger or smaller amounts or for longer than recommended. To use the powder form of this medicine, measure your dose with the medicine cap on the bottle. This cap should contain dose marks on the inside of it. Pour the powder into 4 to 8 ounces of a cold or hot beverage such as water, juice, soda, coffee, or tea. Stir this mixture and drink it right away. Do not save for later us...

If your doctor has directed you to use this Tell your doctor right away if you have A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking this Before using this medication, tell your doctor or pharmacist your medical history, especially of: Older adults may be more sensitive to the side effects of this drug, especially During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into

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Polyethylene Glycol Description A white powder for reconstitution. Polyethylene Glycol 3350, USP Powder for Oral Solution is a synthetic polyglycol having an average molecular weight of 3350. The actual molecular weight is not less than 90.0 percent and not greater than 110.0 percent of the nominal value. The chemical formula is HO(C 2H 4O) nH in which n represents the average number of oxyethylene groups. Below 55°C it is a free flowing white powder freely soluble in water. Polyethylene Glycol 3350, USP Powder for Oral Solution is an osmotic agent for the treatment of constipation. Polyethylene Glycol - Clinical Pharmacology Pharmacology: Polyethylene Glycol 3350, USP Powder for Oral Solution is an osmotic agent which causes water to be retained with the stool. Essentially, complete recovery of Polyethylene Glycol 3350, USP Powder for Oral Solution was shown in normal subjects without constipation. Attempts at recovery of Polyethylene Glycol 3350, USP Powder for Oral Solution in constipated patients resulted in incomplete and highly variable recovery. In vitro study showed indirectly that Polyethylene Glycol 3350, USP Powder for Oral Solution was not fermented into hydrogen or methane by the colonic microflora in human feces. Polyethylene Glycol 3350, USP Powder for Oral Solution appears to have no effect on the active absorption or secretion of glucose or electrolytes. There is no evidence of tachyphylaxis. Clinical Trials In one study, patients with less than 3 bowel mo...

Polyethylene Glycol Polyethylene glycol (PEG) is a polymer derived from ethylene oxide is an advantageous component for obtaining solid dispersions due to their physicochemical properties. From: Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics, 2017 Related terms: • Small Hairpin RNA • Oxides • Chitosan • Doxorubicin • In Vitro • In Vivo • Brain • Aqueous • Copolymer H.-W. Leung, in Encyclopedia of Toxicology (Third Edition), 2014 Chronic Toxicity Animal Long-term feeding and drinking water studies in rats and dogs and skin application studies in rabbits revealed that polyethylene glycols have very low toxicity. No adverse effects were observed in mice and rats exposed to concentrations of 1000mgm −3 of PEG-200 aerosol for 6h a day, 5 days a week, for 13 weeks. Nephrotoxicity and hepatotoxicity have been observed in dogs and monkeys after continuous intravenous infusion of high doses of polyethylene glycol. Human There are several published reports of hyperosmolality, metabolic acidosis, and subsequent renal failure resulting from the application of enormous quantities of polyethylene glycol ointments (as much as 13 kg) to burn patients. These effects may reflect the compromised kidney function of the severely stressed patient rather than the direct nephrotoxic effects of polyethylene glycols. Poly(ethylene glycol) (PEG) is a water-soluble polymer with a wide range of biomedical applications. Because of its uncharged and hydrophilic nature, it is h...