Promethazine

Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures . Promethazine may also be used for other conditions as determined by your doctor . This medicine is only available with your doctor's prescription . This product is available in the following dosage forms: • Syrup • Tablet Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Appropriate studies have not been performed on the relationship of age to the effects of promethazine in the pediatric population. Safety and efficacy have not been established in children below 2 years of age. Caution should be used when this medicine is given to children 2 years of age and older . Geriatric Insufficient information is available on the relationship of age to the effects of promethazine in geriatric patients. However, elderly patients may be more s...

Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Codeine belongs to the group of medicine called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: • Syrup Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Pediatric Use of promethazine and codeine combination is not recommended in children younger than 6 years of age for syrup or in children younger than 12 years of age for oral solution, because of the increased risk of respiratory depression. Promethazine and codeine combination should not be used to relieve pain after surgery to remove tonsils or ade...

Promethazine Pregnancy and Breastfeeding Warnings Promethazine is also known as: Adgan, Anergan 50, • • Promethazine Pregnancy Warnings Animal models have failed to reveal evidence of teratogenicity at doses 2.1 to 4.2 times the maximum recommended human dose. When animal models were given intraperitoneal doses, fetal mortality occurred. There are no controlled data in human pregnancy. AU TGA pregnancy category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible. Accompanying texts should be consulted for further details. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus. AU TGA pregnancy category: C US FDA pregnancy category: C Comments: -Some experts recommend avoiding use 2 weeks prior to delivery due to reports of irritability, excitement, and inhibited platelet aggregation in exposed neonates. -High doses given later in pregnancy have resulted in prolonged neurological/extrapyramidal disturbances in the neonate. Promethazine Breastfeeding Warnings Use is not recommended and a decision should be made to discontinue bre...