Vitamin deficiency anemia is a lack of healthy red blood cells caused by lower than usual amounts of vitamin B-12 and folate. This can happen if you don't eat enough foods containing vitamin B-12 and folate, or if your body has trouble absorbing or processing these vitamins.

Megaloblastic anemia is caused by deficiency or impaired utilization of vitamin B12 and/or folate, whereas nonmegaloblastic macrocytic anemia is caused by various diseases such as myelodysplastic syndrome ( MDS ), liver dysfunction, alcoholism, hypothyroidism, certain drugs, and by less commonly inherited disorders of DNA synthesis.

The most significant problem with microcytic anemia is that its symptoms can be mild or develop over time. You may not notice changes in your body right away that are signs something isn’t right. Microcytic anemia is a sign of other anemias and medical conditions that, if left untreated, may cause serious medical problems.

noun : an anemia (as pernicious anemia) characterized by the presence of megaloblasts in the circulating blood Dictionary Entries Near megaloblastic anemia megaloblast megaloblastic anemia megalocephaly See More Nearby Entries Cite this Entry Style “Megaloblastic anemia.”

Megaloblastic macrocytic anemia: This form of macrocytic anemia happens when you don’t get enough vitamin B12 and/or vitamin B9 (folate). Without these nutrients, your bone marrow can’t make healthy red blood cells able to carry oxygen throughout your body. The unhealthy cells also die earlier than normal.

Diet. Certain restrictive diets can lead to low levels of folate or B-12 because the child does not get enough of these nutrients. What are the symptoms of megaloblastic anemia in a child? These are some of the symptoms of megaloblastic anemia: Pale or yellow skin Fast heart beat Shortness of breath Lack of energy, feeling tired Decreased appetite

Megaloblastic anemia is an anemia that results from inhibition of DNA synthesis in red blood cell production. When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis stage. This leads to continuing cell growth without division, which presents as macrocytosis.