Total GH secretory rate (ng/ mL /12.5 h) was significantly greater in the HIE than the CON ( P = 0.05), but MOD was not different from CON or HIE. Nocturnal GH secretion (ng/ mL /7.5 h) was not different between the three trials. For these women, in this pilot study, a single bout of HIE was sufficient to increase 12.5 h pulsatile GH secretion.