Sickle cell anaemia upsc

  1. SICKLE CELL ANAEMIA
  2. How is India addressing sickle cell anaemia?
  3. Genetic Disorders
  4. World Sickle Cell Disease Day 2021
  5. Sickle Cell Anemia
  6. What is Sickle Cell Disease?


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SICKLE CELL ANAEMIA

• Home • Create Notes • Create Questions • Current Affairs • Previous year questions • Editorials • Books • Paid Books • Today Newspapers • Daily Quiz • CSAT Daily Quiz • Prelims Test Series • Mains Test Series • Mock Tests (APPSC GROUP 1) • Practice questions • Articles • Blogs • Tutors list • Download App Now Union Finance Minister Nirmala Sitharaman, while presenting the Union Budget, declared Sickle cell Anaemia as a national mission. 2. Key Points • Way back in 2019, Prof Sudam Laxman Kate, emeritus scientist with the Indian Council of Medical Research (ICMR) and Former Deputy Director of the Tribal Health Research project, at B.J. Medical College, Pune, was crusading to help tribals suffering from Sickle Cell Anaemia. • He has done pioneering research in Sickle Cell Disease, especially among tribal populations of India. • He was the first scientist to find Sickle Cell disorder in the tribes of north Maharashtra in 1972. Diseases of the Poor often get neglected in discussions on health. • He set up two centres dedicated to Sickle Cell anaemia in northern Maharashtra and a community health care centre in 1998 called "Sickle cell Dawakhana" in the remote Satpuda, under the aegis of Maharashtra Arogya Mandal Hadapsar, Pune. 3. Nature of the disease • It is an inherited genetic disease where a point mutation in haemoglobin makes it abnormal and prone to structural change. • This causes the red blood cells to take an abnormal " sickle" shape, which obstructs blood flow. • ...

How is India addressing sickle cell anaemia?

• Open menu • • • • • • • • • • • • • • • • • • Open menu • • • • • • • • • • • • • • • • • Open menu • • • • • • • • • • • • • • • • • • • • • • • • • • • Open menu • • • • • • • • • • Open menu • • • • • • • • • • • • • • • • • • • • • • • Open menu • • • • • • • • • • • Open menu • • • • • • • • • • • • • Open menu • • • • • • • • • Open menu • • • List of Contents • • • • • Source: The post is based on the article “How is India addressing sickle cell anaemia?” published in The Hindu on 20th February 2023 What is the News? In Budget 2023-24, the Finance Minister has said that the government will work in “mission mode” to eliminate Sickle Cell Anaemia(SCA) by 2047. Note: India is the second-worst affected country in terms of predicted births with SCA — i.e. chances of being born with the condition. What is Sickle Cell Anaemia? Haemoglobin which is tasked with carrying oxygen to all parts of the body has four protein subunits — two alpha and two betas. In some people, mutations in the gene that creates the beta subunits impact the shape of the blood cell and distort it to look like a sickle. A round red blood cell can move easily through blood vessels because of its shape but sickle red blood cells end up slowing and even blocking, the blood flow. Moreover, sickle cells die early, resulting in a shortage of red blood cells that deprive the body of oxygen. These obstructions and shortages may cause chronic anaemia, pain, fatigue, acute chest syndrome, stroke and a host of ...

Genetic Disorders

• About us • • • • • • • Prelims • • • • • • • • • • • • • • • • • • • • Practice Quiz • • • • • • • • • • • • • • • • • Mains & Interview • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • Current Affairs • • • • • • • • • Drishti Specials • • • • • • • • • • • • • • • Test Series • • • • • • • • • • • • • • • • • • • • • State PCS • • • • • • • • • Videos • • • • • • • • • • • • • • • • • • • • • • • • • • • Quick Links Tags: • • The government is setting up specialist laboratories in the country to conduct tests for genetic diseases, which is a leading cause of death among infants and children in the poorest districts across the country. • There are 117 aspirational districts that lack such diagnostic facilities. • The laboratories will run under the Human Genetics and Genome Analysis Programme under the Department of Biotechnology, Ministry of Science and Technology. • The programme addresses issues related to specific inherited diseases concerning the Indian population. Genetic Disorders in India • Common genetic disorders in India are Beta-Thalassemia, Cystic Fibrosis, Sickle Cell Anaemia, Spinal Muscular Atrophy and • Beta thalassemia is a blood disorder that reduces the production of hemoglobin. • Cystic fibrosis is a disorder that causes severe damage to the lungs, digestive system and other organs in the body. • Sickle cell anemia, or sickle cell disease (SCD), is a genetic disease of the red blood cells (RBCs). • Spinal muscular atrophy is a disorde...

World Sickle Cell Disease Day 2021

Tags: • • • Why in News To commemorate the World Sickle Cell Disease (SCD) Day on 19 th June, the Ministry of Tribal Affairs (MOTA) flagged off mobile vans under the Unmukt project for strengthening screening and timely management of SCD in tribal districts of Jharkhand and Chhattisgarh. • The 22 th December, 2008. • The UNGA also recognised SCD as one of the first Key Points • Sickle Cell Disease: • It is an inherited blood disease which is most common among people of African, Arabian and Indian origin. • It is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. • People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent shape. • This blocks blood flow and oxygen from reaching all parts of the body. • Symptoms: • It can cause severe pain, referred to as sickle cell crises. • Over time, people with sickle cell disorders can experience damage to organs including the liver, kidney, lungs, heart and spleen. Death can also result from complications of the disorder. • Treatment: • Medication, blood transfusions and rarely a bone-marrow transplant. • Related Data: • India alone is home to about 1,50,000 patients with SCD and about 88% of Sickle Cell Anemia (SCA) cases in Asia. • The disease in India occurs predominantly in eastern Gujarat, Maharashtra, Madhya Pradesh, Chhattisgarh, western Odisha and in pockets of the Ni...

Sickle Cell Anemia

Focus: GS II: Health Why in News? The Government of India, through the National Health Mission, is supporting the states in their efforts to prevent and manage sickle cell disease. In Union Budget 2023-24, the government has announced a mission to eliminate Sickle cell Anaemia by 2047. Sickle Cell Anemia • Sickle cell anemia is a genetic blood disorder in which the red blood cells take on a crescent shape, making it difficult for the cells to pass through small blood vessels and causing blockages. Symptoms The symptoms of sickle cell anemia can vary from person to person, but common symptoms include: • Painful episodes (sickle cell crisis) • Anemia • Fatigue and weakness • Shortness of breath • Delays in growth and development • Joint pain • frequent infections Treatment Currently, there is no cure for sickle cell anemia, but treatments are available to manage the symptoms and prevent complications. • Pain management • Blood transfusions • Antibiotics to prevent infections • Hydoxyurea, a medication to reduce the frequency of sickle cell crises • Stem cell transplantation in some cases Indian Government Initiatives to reduce Sickle Cell Anaemia • Government has released technical operational guidelines for prevention and control of hemoglobinopathies in 2016 including sickle cell anaemia. • Integrated centers have also been established in 22 tribal districts for treatment and diagnosis. • The State Haemoglobinopathy Mission has been established in Madhya Pradesh ...

What is Sickle Cell Disease?

Our today's edition of Current Affairs is here. Read to know more about Sickle Cell Disease. Also, find the topic's relevance to the UPSC CSE syllabus below: For Prelims: General Science Sickle Cell Disease, Symptoms of Sickle Cell Disease, Diagnosis of Sickle Cell Disease, Stem cell transplantation, National Health Mission, Sickle Cell Disease Support Corner, Unmukt Project, National Council on Sickle Cell Disease and Tribal Health Cell. For Mains: General Studies Paper II (Health) & General Studies Paper III (Government Budgeting) Context The union budget of FY 2023-24 announced a mission to eliminate sickle cell anaemia by 2047. • The mission entails focus on awareness creation, universal screening of approximately seven crore people in the 0-40 years age group in affected tribal areas and counselling through collaborative efforts of central ministries and state governments. Probable Question The Government's target of eliminating sickle cell anaemia in the nation by 2047 is a very positive step as it will also aid in combating the endemic haematological illness like anaemia that plague the nations indigenous communities. Explain. (150 words, 10 marks). Related Data • With around 18 million people with sickle cell traits and 1.4 million patients with sickle cell disease, India is expected to have the second-highest numbers in the world. • A few states in India have a significantly higher SCD prevalence: Chhattisgarh, West Bengal, Uttar Pradesh, Maharashtra, Madhya Prade...