Terbutaline sulphate

What are Terbutaline Sulfate Tablets for Cats and Dogs? • Terbutaline is a prescription medication that eases labored breathing and wheezing in dogs and cats suffering from asthma, bronchitis, and other conditions that make breathing difficult. • Terbutaline relaxes constricted airways so your pet can breathe more steadily. • Terbutaline is the generic drug name for the brand Brethine. Why do cats and dogs use Terbutaline? • Terbutaline may be prescribed for dogs and cats suffering breathing problems due to asthma, collapsing trachea, allergic bronchitis and some lung diseases. What else should I know about Terbutaline? • Effective for dogs and cats with asthma, allergic bronchitis, tracheobronchitis, and some lung diseases. • Eases breathing. What problems could my dog or cat have with Terbutaline? • Overdoses of Terbutaline can be serious. Keep the tablets out of reach of children and animals. • Terbutaline may increase heart rate and cause excitement. • Terbutaline can also delay labor in pregnant animals. How do you use Terbutaline? • Give Terbutaline by mouth as directed by your veterinarian. What is in Terbutaline? • The drug Terbutaline Sulfate is a bronchodilator that works by relaxing constricted airways. • Terbutaline stimulates certain receptors in the airways so they open, or dilate, and make breathing easier. Will I get what I see in the picture? • Terbutaline is sold as an FDA approved generic drug. Brand may vary from order to order and variation to variatio...

WARNING: PROLONGED TOCOLYSIS Terbutaline sulfate has not been approved and should not be used for prolonged tocolysis (beyond 48-72 hours). In particular, Terbutaline sulfate should not be used for maintenance tocolysis in the outpatient or home setting. Serious adverse reactions, including death, have been reported after administration of Terbutaline sulfate to pregnant women. In the mother, these adverse reactions include increased heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema and myocardial ischemia. Increased fetal heart rate and neonatal hypoglycemia may occur as a result of maternal administration (see Terbutaline Description Terbutaline Sulfate, USP, the active ingredient of Terbutaline Sulfate Injection, USP, is a beta‑adrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each milliliter of solution contains 1 mg of Terbutaline Sulfate, USP (0.82 mg of the free base), sodium chloride for isotonicity, 0.055% edetate disodium dihydrate as a stabilizing agent, and hydrochloric acid for adjustment to a target pH of 4. Terbutaline sulfate is (±)-a-[( tert‑butylamino) methyl]-3,5-dihydroxybenzyI alcohol sulfate (2:1) (salt). The molecular formula is (C 12H 19N0 3) 2•H 2SO 4 and the structural formula is: Related/similar drugs Terbutaline - Clinical Pharmacology Terbutaline sulfate injection is a beta-adrenergic receptor agonist. In vitro and in vivo phar...

Number:0468 Policy Aetna considers magnesium sulfate injections medically necessary for short-term prolongation of pregnancy (up to 48 hours) in pregnant women who are at risk of preterm delivery within 7 days. Aetna considers the use of a terbutaline pump for administration of subcutaneous terbutaline experimental and investigational for the prevention or treatment of premature labor becauase its effectiveness has not been established. See also Background Terbutaline for Preterm Labor Terbutaline has been used in selected patients to inhibit uterine contractions in preterm labor (tocolysis) in an attempt to prolong pregnancy and prevent preterm birth. An infusion pump is required for the subcutaneous administration of terbutaline. Preterm labor often results in preterm births, which significantly contributes to infant morbidity and mortality. There is no evidence that tocolytics reduces the risk of preterm delivery (Haas, 2007; Nanda et al, 2002; CTAF, 2002). The incidence of preterm birth has not decreased in the last 2 decades, despite the increased use of tocolytics. A review of 17 randomized controlled trials (RCTs)that compared a tocolytic with a placebo or no tocolytic for women in preterm labor found that tocolytics were not associated with significant reduction in births before 30 weeks' gestation, before 32 weeks' gestation, or before 37 weeks' gestation. However, tocolytics were associated with significant decreases in the likelihood of delivery within 24 hours....

Dosage Forms & Strengths tablet • 2.5mg • 5mg injectable solution • 1mg/mL Bronchospasm PO • Initiate at 2.5 mg three/four times daily PO • Maintenance: 5 mg three times daily PO q6hr while patient is awake; reduce dose to 2.5 mg q6hr • Not to exceed 15 mg/Day SC • 0.25 mg q15-30min x 3 doses PRN in lateral deltoid • Not to exceed 0.5 mg/4 hr Preterm Labor (Off-label) Initiate at 2.5-5 mcg/min IV Increase gradually as tolerated at 20-30 minute intervals Typical effective dose ranges between 17.5-30 mcg/min IV; some require doses up to 70-80 mcg/min Continue infusion for 12 hr following cessation of uterine contractions; not to exceed 48-72 hr PO use or prolonged IV use not recommended (see Black Box Warnings) Renal Impairment GFR 50mL/min: Dose adjustment not necessary Dosage Forms & Strengths tablet • 2.5mg • 5mg injectable solution • 1mg/mL Bronchospasm PO • 15 years: 5 mg/dose PO q8hr three times daily; reduce dose to 2.5 mg q6hr; not to exceed 15 mg/24hr SC (in lateral deltoid) • 12 years: 0.25 mg q15-30min x 3 doses PRN in lateral deltoid; not to exceed 0.5 mg/4 hr Contraindicated (0) Serious - Use Alternative (18) • amitriptyline amitriptyline, terbutaline. Other (see comment). Avoid or Use Alternate Drug. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. • amoxapine amoxapine, terbutaline. Other (see comment). Avoid or Use Altern...

WARNING: PROLONGED TOCOLYSIS Terbutaline sulfate has not been approved and should not be used for prolonged tocolysis (beyond 48 to 72 hours). In particular, terbutaline sulfate should not be used for maintenance tocolysis in the outpatient or home setting. Serious adverse reactions, including death, have been reported after administration of terbutaline sulfate to pregnant women. In the mother, these adverse reactions include increased heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema and myocardial ischemia. Increased fetal heart rate and neonatal hypoglycemia may occur as a result of maternal administration (see ). DESCRIPTION Terbutaline Sulfate Injection, USP, is a beta-adrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each mL of solution contains: 1 mg of terbutaline sulfate USP (0.82 mg of the free base), and Water for Injection, USP. Sodium chloride is used for isotonicity, and hydrochloric acid for adjustment to a pH of 3.0 to 5.0. Terbutaline sulfate is (±)-α-[( tert -butyl-amino) methyl]-3,5-dihydroxybenzyl alcohol sulfate (2:1) (salt). The structural formula is: (C 12 H 19 NO 3 ) 2 • H 2 SO 4 M.W. 548.65 Terbutaline sulfate USP is a white to gray-white crystalline powder. It is odorless or has a faint odor of acetic acid. It is soluble in water and in 0.1N hydrochloric acid, slightly soluble in methanol, and insoluble in chloroform. CLINICAL PH...

What Is Terbutaline Sulfate? Terbutaline Sulfate Injection is a beta-adrenergic receptor agonist used for the prevention and reversal of bronchospasm in patients 12 years of age and older with What Are Side Effects of Terbutaline Sulfate? Terbutaline Sulfate may cause serious side effects including: • uncontrollable shaking, • nervousness, • dizziness, • drowsiness, • difficulty falling asleep or staying asleep, • weakness, • headache, • nausea, • sweating, and • dry mouth Get medical help right away, if you have any of the symptoms listed above. Common side effects of terbutaline sulfate injection include: • • nervousness, • dizziness, • headache, • drowsiness, • • rapid heart rate, • shortness of breath, • chest discomfort, • nausea, • vomiting, • weakness, • flushed feeling, • sweating, • pain at the injection site, • anxiety, • muscle cramps, and • Seek medical care or call 911 at once if you have the following serious side effects: • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out; • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors. This document does not contain all possible side ...