Varicella

VZV transmission occurs via droplets, aerosols, or direct contact with respiratory secretions, and almost always produces clinical disease in susceptible individuals. While mostly a mild disorder in childhood, varicella tends to be more severe in adults. It may be fatal, especially in neonates and in immunocompromised persons. In temperate climates most cases occur before the age of 10. Varicella is characterized by an itchy, rash usually starting on the scalp and face and initially accompanied by fever and malaise. The rash gradually spreads to the trunk and extremities. The vesicles gradually dry out and crusts appear which then disappear over a period of one to two weeks. The infection may occasionally be complicated by pneumonia or encephalitis (inflammation of the brain), at times with serious or fatal consequences. Shingles is a painful rash that may occasionally result in permanent damage to the nerves or visual impairment. It is relatively common in HIV-infected persons, sometimes with fatal consequences. Varicella Vaccines Current varicella vaccines are attenuated vaccines based on the Oka VZV strain that has been modified through sequential propagation in different cell cultures. The attenuated strain is grown in cell culture, purified and lyophilized. Reconstituted vaccine is injected subcutaneously. Varicella vaccine has also been included in a combination vaccine with mesles mumps rubella (MMRV). A vaccine which contains higher level of the virus has also been...

The chickenpox (varicella) vaccine can prevent you or your child from getting chickenpox. The varicella vaccine is given in two doses. Side effects are usually mild and can include pain, redness and swelling at the injection site. Serious reactions are rare. All children ages 12 months and older and most adults should get the chickenpox vaccine. Overview What is the chickenpox vaccine? The chickenpox vaccine can protect you or your child from What does the chickenpox vaccine do? The chickenpox vaccine can prevent chickenpox. Every year, the chickenpox vaccine prevents more than 3.5 million cases of chickenpox, 9,000 hospitalizations and 100 deaths in the U.S. When did the chickenpox vaccine come out? Healthcare providers started giving the chickenpox vaccine in 1995. Chickenpox used to be a very common childhood disease. Before the chickenpox vaccine became available, about 4 million people got chickenpox each year. Between 10,500 and 13,000 people were hospitalized, and 100 to 150 people died each year from chickenpox. Who should get the chickenpox vaccine? All children ages 12 months and older — as well as adults who haven’t had chickenpox — should receive the chickenpox vaccine. This is especially important for adults who are: • Healthcare professionals. • Teachers. • Daycare workers. • Nursing home staff and residents. • College • Correctional institution staff and inmates. • Military personnel. • • Not pregnant but of child-bearing age. Who should not get the chickenp...

Varicella zoster virus ( VZV), also known as human herpesvirus 3 ( HHV-3, HHV3) or Human alphaherpesvirus 3 ( Human alphaherpesvirus 3 Human alphaherpesvirus 3 virion (unranked): Realm: Duplodnaviria Kingdom: Heunggongvirae Phylum: Peploviricota Class: Herviviricetes Order: Herpesvirales Family: Herpesviridae Genus: Varicellovirus Species: Main article: Primary varicella zoster virus infection results in Shingles In about a third of cases, VZV can also infect the central nervous system, with a 2013 article reporting an incidence rate of 1.02 cases per 100,000 inhabitants in Switzerland, and an annual incidence rate of 1.8 cases per 100,000 inhabitants in Sweden. Shingles lesions and the associated pain, often described as burning, tend to occur on the skin that is innervated by one or two adjacent sensory nerves, almost always on one side of the body only. The skin lesions usually subside over the course of several weeks, while the pain often persists longer. In 10–15% of cases the pain persists more than three months, a chronic and often disabling condition known as This section is missing information about Annotated ORFs, like we did for HSV. (Or at least the interesting parts -- maybe differences from HSV?) Please expand the section to include this information. Further details may exist on the ( November 2021) The genome was first sequenced in 1986. S (inverted S) which are present with equal frequency for a total frequency of 90–95%. The L segment can also be inverted ...

The However, the above ages are not the only times you can receive the vaccine. Experts encourage almost anyone who hasn’t received the vaccine or who hasn’t had chickenpox to get the vaccine. Experts especially encourage • work in healthcare or the military • live or work with children, in a correctional facility, or in a group home or group living situation • may become pregnant • plan to do extensive international travel Varicella vaccine schedule for adults Almost anyone more than 13 years old can get two doses of the varicella vaccine. Doctors need to give these doses at least How long is the varicella vaccination good for? Two doses of the varicella vaccine usually give lifetime protection. There is currently no recommendation for a varicella booster. The varicella vaccine is usually safe. However, all vaccines can have side effects. Side effects of the varicella vaccine are typically mild and generally resolve on their own within a day or two. • redness or discoloration • • rash • pain Very rarely, more serious effects do occur. These side effects can be symptoms of a serious • • face or throat swelling • • weakness • • The varicella vaccine typically protects against chickenpox. The vaccine is usually effective at preventing chickenpox for more than 90% of people who receive it. The CDC recommends that children receive their first dose of the vaccine between 12 and 15 months old and a second dose between 4 and 6 years old. Many people more than 13 years old can rec...