Vasopressor

This class of drugs can be lifesaving in emergency medical situations. Vasopressors are a group of medicines that contract (tighten) blood vessels and raise blood pressure. They're used to treat severely low blood pressure, especially in people who are critically ill. Very low blood pressure can lead to organ damage and even death. These drugs can help doctors treat patients who are in shock or are undergoing surgery. Vasopressors have been used since the 1940s. They're commonly given in combination with medicines called inotropes (which affect cardiac muscle contraction). Common Vasopressors Medicines — including synthetic hormones — that are used as vasopressors include: • • • • • • Vasopressor Precautions Vasopressors should only be given under the supervision of a medical professional. These are powerful drugs, and they can be dangerous if used incorrectly. The medicines may reduce blood flow to some parts of the body. Vasopressors are commonly given in an emergency situation, but if you can, tell your doctor if you have any of the following conditions before receiving a vasopressor: • High blood pressure • Diabetes • Heart disease • Circulation problems • A history of blood clots • An • Varicose veins • Asthma • Allergies to medications Side Effects of Vasopressors Tell your doctor if you experience any of the following serious side effects after receiving a vasopressor: • Slow or uneven heartbeat • Blue lips or fingernails • Pain, burning, irritation, or discoloratio...

• Basic anatomy & physiology • Introduction to ECG Interpretation • Arrhythmias and arrhythmology • Myocardial Ischemia & Infarction • Conduction Defects • Cardiac Hypertrophy & Enlargement • Drugs & Electrolyte Imbalance • Genetics, Syndromes & Miscellaneous • Exercise Stress Testing (Exercise ECG) • Pacemaker & CRT • Pediatric & neonatal ECG • ECHO • SCA & CPR • TAKE A TEST • POPULAR Inotropes and vasopressors Vasopressors induce vasoconstriction and increase mean arterial pressure (MAP). Inotropes increase cardiac contractile force (contractility). Several endogenous and synthetic agents exist and are frequently combined to achieve the desired hemodynamic outcome. Most agents exhibit both vasopressor and inotropic effects (Figure 1). Below follows a drug manual for use in the CCU (coronary care unit), ICU (intensive care unit) or ER (emergency room). Careful electrocardiographic and hemodynamic monitoring with Overview of vasopressors and inotropes Inotropes and vasopressors. Table 1. Drug manual for inotropes and vasopressors Drug Indications Dose α1 effect β1 effect β2 effect D1/D2 effect Result Side Effects Dopamine – low dose Rarely used Low dose: 0.5-3.0 μg/kg/min + + + +++++ Low dose dopamine stimulates D1 receptors and induces vasodilation in coronary, renal, cerebral and mesenteric vessels. Few Dopamine – medium dose Cardiogenic shock Vasodilatory shock Heart failure (HF), chronic Medium dose: 3.0-10.0 μg/kg/min. + ++++ + +++++ Medium dose dopamine activates β1,...

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Overview What is a vasopressor? A vasopressor is a drug that healthcare providers use to make Healthcare providers usually give vasopressors through a central venous catheter, or central line, which is an IV tube that goes into a large vein. You may have fewer complications if it’s in your chest or neck instead of your arm. What do vasopressors do? Vasopressors constrict or tighten your blood vessels, making your Common vasopressors Healthcare providers can treat you with these vasopressor drugs: • • • • • • • Terlipressin. Vasopressor examples • You’re using a vasopressor when you use a nasal decongestant. Ephedrine and pseudoephedrine in these products constrict the blood vessels inside your • You have epinephrine in your pocket if you have a nut allergy and carry an EpiPen® Auto-Injector or Adrenalin® in case of an allergy attack. • If you take Sudafed PE Cold/Cough®, Theraflu Cold and Cough® or many other cold or allergy medicines, you’re taking phenylephrine. Vasopressors vs. inotropes Healthcare providers often use both vasopressors and inotropes to help people who have shock or another condition with very low blood pressure. The two drugs have different jobs, though. Vasopressors make your blood vessels narrower to increase your blood pressure. Inotropes help your heart pump more blood. Together, these two drugs can help your body send more blood to your organs so they can keep running. Who needs to have vasopressors? Healthcare providers use vasopressors to increas...

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"Vasopressor" redirects here. It is not to be mistakenly equated with An antihypotensive agent, also known as a vasopressor agent or simply vasopressor, or pressor, is any substance, whether If low blood pressure is due to blood loss, then preparations increasing volume of blood circulation—plasma-substituting solutions such as colloid and crystalloid solutions (salt solutions) [ medical citation needed] Blood products should only be used if reduced oxygen carrying capacity or coagulopathy is present. [ medical citation needed] Other causes of either absolute (dehydration, loss of plasma via wound/burns) or relative ( Classification [ ] Antihypotensive agents can be classified as follows: [ citation needed]