Cholecalciferol

You can get vitamin D3 from sun exposure and meat, such as fish oil and egg yolk. You can get vitamin D2 from plants. Vitamin D is more than just one vitamin. It’s a family of nutrients that shares similarities in chemical structure. In your diet, the most commonly found members are vitamin D2 and D3. While both types help you meet your vitamin D requirements, they differ in a few important ways. Research even suggests that vitamin D2 is less effective than vitamin D3 at raising blood levels of vitamin D. This article sums up the main differences between vitamin D2 and D3. Your skin produces vitamin D when it’s exposed to sunlight. However, if you spend most of your time indoors or live at a high latitude, you’ll need to get this vitamin from your diet. Good dietary sources include fatty fish, fish oils, egg yolk, butter and liver. However, it may be difficult to get adequate amounts of this vitamin from your diet alone, as rich natural sources are rare. For these reasons, it’s common for people to not get enough. Luckily, many food manufacturers add it to their products, especially milk, margarine and breakfast cereals. Supplements are also popular. To prevent Since vitamin D is fat-soluble, it is better to choose oil-based supplements or take them with food that contains some fat ( The vitamin comes in two main forms: • Vitamin D2 (ergocalciferol) • Vitamin D3 (cholecalciferol) Their differences are discussed in detail below. Summary Vitamin D is a fat-soluble vitamin th...

Add a drug to check interactions Add • • View (5) Most frequently checked interactions View interaction reports for cholecalciferol and the medicines listed below. • Major • Moderate • Minor • Unknown • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • Cholecalciferol disease interactions There are • • • • • Drug Interaction Classification These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown No interaction information available. Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

• العربية • বাংলা • Bosanski • Čeština • Cymraeg • Deutsch • Ελληνικά • Español • Euskara • فارسی • Français • Galego • हिन्दी • Bahasa Indonesia • Italiano • Magyar • Bahasa Melayu • Minangkabau • Nederlands • 日本語 • ଓଡ଼ିଆ • Polski • Português • Română • Русский • Slovenčina • Slovenščina • Српски / srpski • Srpskohrvatski / српскохрватски • Sunda • Türkçe • Українська • Tiếng Việt • 中文 Key:QYSXJUFSXHHAJI-YRZJJWOYSA-N Cholecalciferol, also known as vitamin D 3 and colecalciferol, is a type of Cholecalciferol is made in the skin following Cholecalciferol can be taken as an oral dietary supplement to prevent μg) per day are generally required before Cholecalciferol was first described in 1936. million prescriptions. Medical uses [ ] Cholecalciferol appears to stimulate the body's Vitamin D deficiency [ ] Main article: Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to 6) • In the US: 15μg/d (600 IU per day) for all individuals (males, females, pregnant/lactating women) between the ages of 1 and 70 years old, inclusive. For all individuals older than 70 years, 20μg/d (800 IU per day) is recommended. • In the EU (except France): 20μg/d (800 IU per day) • In France: 25μg/d (1000 IU per day) Low levels of vitamin D are more commonly found in individuals living in northern latitudes, or with other reasons for a lack of regular sun exposure, including being housebound, frail, elderly, obese, having darke...

If you are using this medicine without a prescription, follow the instructions on the package. The chewable wafer must be chewed or crushed. Do not swallow the wafer whole. Using the oral liquid: • Use the dropper that comes with the package to measure your dose. • Adults and adolescents: Drop the liquid directly into the mouth or mix it with food or other liquids (eg, water or juice). • Children 2 years of age and older: Drop the liquid directly into the mouth, mix it with food or other liquids (eg, water or juice), or take it from a spoon. • Children younger than 2 years of age: Place one drop of the liquid on the pacifier, mother's nipple, or bottle nipple and allow baby to suck for at least 30 seconds. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. • For vitamin D deficiency: • For oral dosage form (capsules): • Adults—One capsule containing 5000 international units (IU) once a day. • Children—Use and dose must be determined by your doctor. • For oral dosage form ...

Olga Shumitskaya / Getty Images Why You Need Vitamin D Vitamin D, also referred to as calciferol, is a fat-soluble vitamin (meaning one that is broken down by fat and oils in the gut). It is commonly referred to as the "sunshine vitamin" because the D3 type can be naturally produced in the body following exposure to the sun. • Vitamin D2 is naturally found in mushrooms, including shiitake, Portobello, and crimini mushrooms. The vitamin D content increases when these mushrooms are exposed to UV radiation. • Vitamin D3 is naturally found in animals and animal-derived products like milk. It is also directly synthesized in the skin when it is exposed to ultraviolet B (UVB) radiation. Some studies suggest that vitamin D3 raises the vitamin D level in the bloodstream 87% more than vitamin D2. On the downside, vitamin D3 in supplements has historically been synthesized using lanolin derived from sheep's wool. This makes it unsuitable for those who choose to avoid animal-based products. Food IU Serving size % RDA Beef liver 42 3 ounce 5% Butter 9 1 tablespoon 1% Cereal 80 1-1/2 ounce 10% Cheese 12 1 ounce 2% Cod liver oil 1,360 1 tablespoon 170% Egg yolks 44 1 yolk 6% Fresh salmon 570 3 ounce 71% Halibut 384 1/2 fillet 48% Mackerel 360 1/2 fillet 45% Milk, fortified 120 1 cup 15% Sardines 46 2 fish 6% Trout 645 3 ounce 81% Tuna 40 3 ounce 5% • National Institutes of Health Office of Dietary Supplements. • US Preventive Services Task Force, et al. JAMA. 2021;325(14):1436-1442 . doi...

In the United States, vitamin D supplementation is primarily available as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Although these two have historically been considered interchangeable and equipotent, the current body of literature strongly supports the preference of Vitamin D3 (cholecalciferol) over D2 (ergocalciferol). Vitamin D2 versus Vitamin D3 Vitamin D3 (cholecalciferol) is produced by the human body in response to sunlight and is also available through dietary sources, such as fish. In contrast, vitamin D2 (ergocalciferol) is not produced in the human body, but is created by exposing certain plant-derived materials to ultraviolet light. When the manufacturing method for ergocalciferol was created, binding studies of the vitamin D receptor in rats showed equipotency between ergocalciferol and cholecalciferol. On the basis of this animal data, most resources cite the two being equipotent and interchangeable. Given that both ergocalciferol and cholecalciferol undergo metabolic changes in the human body, which differ from other animals, it should make sense that a binding study in rats may not be sufficient to show equivalence. In fact, recent literature (Trang 1998, Armas 2004, Houghton 2006) convincingly demonstrates that cholecalciferol is 1.7 to 3 times more potent and has a longer-lasting effect than ergocalciferol in increasing serum 25-hydroxyvitamin D levels, the active form of vitamin D in humans. The difference in duration of effect and po...