Dengue igm antibody positive means

  1. CHIKV
  2. Chikungunya Antibodies, IgG and IgM
  3. IgM and IgG Antibody Testing in Diagnosing Dengue
  4. Dengue Fever Virus Antibodies, IgG & IgM
  5. Serological and molecular epidemiology of the Dengue, Zika and Chikungunya viruses in a risk area in Brazil


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CHIKV

This test may be used as an aid to diagnose recent or past infection with Chikungunya virus (ChikV) in patients with recent travel to endemic regions and a compatible clinical syndrome. IgM and IgG antibodies to ChikV are typically detectable 3 to 4 days and 6 to 7 days following onset of symptoms, respectively. IgM antibodies to ChikV typically remain detectable for 3 to 4 months after infection, whereas IgG antibodies to ChikV remain detectable for years. Chikungunya virus (ChikV) is a single-stranded RNA alphavirus and a member of the Togaviridae family of viruses. The name Chikungunya is derived from the language of the Makonde ethnic groups in southeast Africa and means "that which bends" or "stooped walk." This is in reference to the hunched-over appearance of infected individuals due to the characteristically painful and incapacitating arthralgia caused by the virus. ChikV is endemic throughout Africa, India, and, more recently, the Caribbean islands. In 2014, the first case of autochthonous, or local transmission, in the United States occurred in Florida. Humans are the primary reservoir for ChikV and Aedes species mosquitos are the primary vectors for transmission. Unlike other mosquito-borne viruses, such as West Nile virus and Dengue, the majority of individuals who are exposed to ChikV become symptomatic, with the most severe manifestations observed at the extremes of age and in those with suppressed immunity. Once exposed to ChikV, individuals develop lasting ...

Chikungunya Antibodies, IgG and IgM

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent." Test Code Component Reference Interval 2011808 Chikungunya Antibody, IgG 0.79 Index or less Negative: No significant level of Chikungunya IgG antibody detected. 0.80-1.09 Index Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.10 Index or greater Positive: Chikungunya IgG antibody detected; suggests current or past infection. 2011810 Chikungunya Antibody, IgM 0.79 Index or less Negative: No significant level of Chikungunya IgM antibody detected. 0.80-1.09 Index Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful. 1.10 Index or greater Positive: Chikungunya IgM antibody detected. CPT Codes The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as re...

IgM and IgG Antibody Testing in Diagnosing Dengue

The country is seeing a massive dengue outbreak as thousands of cases are being reported monthly. This is a mosquito-borne illness that begins in the monsoon(mosquito-breeding) season but lingers around till December. There is no treatment for dengue available till date, which makes this a life-threatening condition. Thus, timely diagnosis and management are the only means to deal with dengue. Talking about diagnosis, there are two serotypes of dengue that are tested in a blood sample- IgM and IgG. Let us tell you what these mean and why you should check them. Dengue is preventable and treatable only if you know how to do it. Anyone of any age can get dengue and if this wasn’t enough, a person can get dengue four times in their lifetime as there are four subtypes of dengue. You become immune to the variant you got infected but still susceptible to others. India is one of the most affected countries by dengue as all the four serotypes of dengue are prevalent in India. Also, if a person gets infected with dengue subsequently, it might lead to severe consequences like dengue haemorrhagic fever and shock syndrome. Thus, it is important to track the prognosis of dengue which is only possible through dengue testing. Antibody testing is conducted to find if a person is dengue-positive and its serotype. Serological markers of Dengue fever Dengue virus is present in everyone with dengue fever but the antigen marker changes with the progression of the infection. NS1 antigen occurs b...

Dengue Fever Virus Antibodies, IgG & IgM

Dengue Fever Virus Antibody, IgG 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody. 1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. 2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection. Dengue Fever Virus Antibody, IgM 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody. 1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful. 2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Serological and molecular epidemiology of the Dengue, Zika and Chikungunya viruses in a risk area in Brazil

Background The co-circulation of types of arbovirus in areas where they are endemic increased the risk of outbreaks and limited the diagnostic methods available. Here, we analyze the epidemiological profile of DENV, CHIKV and ZIKV at the serological and molecular level in patients with suspected infection with these arboviruses in the city of Juazeiro do Norte, Ceará, Brazil. Methods In 2016, the Central Public Health Laboratory (LACEN) of Juazeiro do Norte received 182 plasma samples from patients who visited health facilities with symptoms compatible with arbovirus infection. The LACEN performed serological tests for detection of IgM/IgG to DENV and CHIKV. They then sent these samples to the Retrovirology Laboratory of the Federal University of São Paulo and Faculty of Medical of the ABC where molecular analyses to confirm the infection by DENV, ZIKV and CHIKV were performed. The prevalence of IgM/IgG antibodies and of infections confirmed by RT-qPCR were presented with 95% confidence interval. Results In serologic analysis, 125 samples were positive for antibodies against CHIKV and all were positive for antibodies against DENV. A higher prevalence of IgG against CHIKV (63.20% with 95% CI: 45.76–70.56) than against DENV (95.05% with 95% CI: 78.09–98.12) was observed. When the samples were submitted to analysis by RT-qPCR, we observed the following prevalence: mono-infection by ZIKV of 19.23% (95% CI: 14.29–34.82) patients, mono-infection by CHIKV of 3.84% (95% CI...