What is gene

Researchers have found a number of genes that are linked to Alzheimer's disease. Some genes increase the likelihood of getting the disease, called risk genes. Others ensure getting the disease, called deterministic genes. Deterministic genes are rare. However, genes are just part of what's involved in getting Alzheimer's disease. • APOE e2. This is the least common. It reduces the risk of Alzheimer's. • APOE e4. This gene is a little more common. It increases the risk of Alzheimer's. And it's linked to getting a worse form of the disease. • APOE e3. This most common gene doesn't seem to affect the risk of Alzheimer's. Genes aren't the only factor One copy of the APOE gene comes from the mother and another from the father. Having at least one APOE e4 gene doubles or triples the risk of getting Alzheimer's disease. Some people have two APOE e4 genes, one from each parent. Having two genes increases the risk of getting Alzheimer's disease even more, about eight- to twelvefold. But not everyone who has one or even two APOE e4 genes gets Alzheimer's disease. And many people who don't have an APOE e4 gene get the disease. That suggests that the APOE e4 gene increases risk but is not a cause. There's likely more to getting Alzheimer's disease than just genes, such as lifestyle, race, ethnicity and environment. Other late-onset genes As gene research goes on, researchers are finding links between late-onset Alzheimer's and a number of other genes. Examples include: • ABCA7. This g...

• A gene is a small section of • The purpose of • Each gene contains the information required to build specific proteins needed in an organism. • The human • Genes come in different forms, called • In humans, alleles of particular genes come in pairs, one on each • An individual’s • For example, for a gene that determines eye colour there may be several different alleles. One allele may result in blue eyes, while another might result in brown eyes. The final colour of the individual’s eyes will depend on which alleles they have and how they interact. • The characteristic associated with a certain allele can sometimes be

Somatic gene therapy: Somatic gene therapy aims to correct a defect in the DNA of a somatic cell or to provide an RNA molecule to treat or prevent a genetic disease in the person who is undergoing the therapy. This treatment may be used if you have an inherited mutation or if the mutation developed due to environmental factors. Some research using gene augmentation therapy involves the insertion of a healthy DNA molecule or an RNA sequence into a cell, but not into the DNA of the recipient. This has been shown in experimental studies to trigger the production of healthy proteins, but future copies of the cell are not expected to contain the healthy gene. • Cystic fibrosis: An inherited disorder in which thick mucus is produced, clogging the airways and blocking the secretion of digestive enzymes • Sickle cell disease: An inherited disorder that results in abnormal hemoglobin production (the protein that carries oxygen in the red blood cells) • Leber's hereditary optic neuropathy (LHON): An inherited disorder that causes the death of cells in the • Inherited or acquired retinal disease: Conditions that damage to the • WW domain-containing oxidoreductase (WWOX) epileptic encephalopathy syndrome: A genetic condition resulting in severe epilepsy, developmental delays, and early death • Spinocerebellar ataxia and autosomal recessive 12 (SCAR12): An inherited disorder resulting in seizures in infancy, developmental delays, and inability to coordinate movement • Cancer: Many type...

• Afrikaans • Alemannisch • العربية • Asturianu • Azərbaycanca • বাংলা • Bân-lâm-gú • Башҡортса • Беларуская • Беларуская (тарашкевіца) • Български • Bosanski • Català • Čeština • ChiShona • Cymraeg • Dansk • Davvisámegiella • Deutsch • Eesti • Ελληνικά • Español • Esperanto • Euskara • فارسی • Français • Frysk • Gaeilge • Galego • ГӀалгӀай • 한국어 • Հայերեն • हिन्दी • Hrvatski • Ido • Bahasa Indonesia • IsiXhosa • IsiZulu • Íslenska • Italiano • עברית • Jawa • ಕನ್ನಡ • ქართული • Қазақша • Kiswahili • Kreyòl ayisyen • Kriyòl gwiyannen • Kurdî • Кыргызча • Ladin • ລາວ • Latina • Latviešu • Lietuvių • Magyar • Македонски • മലയാളം • მარგალური • مصرى • Bahasa Melayu • 閩東語 / Mìng-dĕ̤ng-ngṳ̄ • Монгол • မြန်မာဘာသာ • Nederlands • नेपाली • 日本語 • Nordfriisk • Norsk bokmål • Norsk nynorsk • Occitan • Oromoo • Oʻzbekcha / ўзбекча • ਪੰਜਾਬੀ • پنجابی • پښتو • Patois • Polski • Português • Română • Runa Simi • Русский • Саха тыла • Scots • Shqip • Sicilianu • සිංහල • Simple English • سنڌي • Slovenčina • Slovenščina • Soomaaliga • Српски / srpski • Srpskohrvatski / српскохрватски • Suomi • Svenska • Tagalog • தமிழ் • తెలుగు • ไทย • Тоҷикӣ • ᏣᎳᎩ • Türkçe • Українська • اردو • Vahcuengh • Tiếng Việt • 文言 • Winaray • 吴语 • ייִדיש • 粵語 • 中文 A gene is a region of In gene (from γένος, generation birth gender) can have several different meanings. The Mendelian gene is a basic unit of During The transmission of genes to an organism's A gene can acquire The term gene was introduced by Danish botanist, ...

The stringy stuff in the test tube is DNA. But you can't tell which one of these organisms it came from just by looking at it. That's because DNA looks exactly the same in every organism on Earth. All living things have DNA. And whether it comes from you, a pea plant, or your pet rat, it's all the same molecule. It's the order of the letters in the code that makes each organism different. The order of building blocks in a strand of DNA makes up a "sequence." We can read a DNA sequence like letters in a book. In fact, we know the sequence of the entire human genome—all 3 billion letters. That's enough information to fill roughly 1,000 200-page books! Contained within the 3 billion letters of the human genome are about 21,000 genes. Most of our known genes code for proteins, but some code for RNA molecules. All humans have the same genes arranged in the same order. And more than 99.9% of our DNA sequence is the same. But the few differences between us (all 1.4 million of them!) are enough to make each one of us unique. On average, a human gene will have 1-3 bases that differ from person to person. These differences can change the shape and function of a protein, or they can change how much protein is made, when it's made, or where it's made.

The stringy stuff in the test tube is DNA. But you can't tell which one of these organisms it came from just by looking at it. That's because DNA looks exactly the same in every organism on Earth. All living things have DNA. And whether it comes from you, a pea plant, or your pet rat, it's all the same molecule. It's the order of the letters in the code that makes each organism different. The order of building blocks in a strand of DNA makes up a "sequence." We can read a DNA sequence like letters in a book. In fact, we know the sequence of the entire human genome—all 3 billion letters. That's enough information to fill roughly 1,000 200-page books! Contained within the 3 billion letters of the human genome are about 21,000 genes. Most of our known genes code for proteins, but some code for RNA molecules. All humans have the same genes arranged in the same order. And more than 99.9% of our DNA sequence is the same. But the few differences between us (all 1.4 million of them!) are enough to make each one of us unique. On average, a human gene will have 1-3 bases that differ from person to person. These differences can change the shape and function of a protein, or they can change how much protein is made, when it's made, or where it's made.

• Afrikaans • Alemannisch • العربية • Asturianu • Azərbaycanca • বাংলা • Bân-lâm-gú • Башҡортса • Беларуская • Беларуская (тарашкевіца) • Български • Bosanski • Català • Čeština • ChiShona • Cymraeg • Dansk • Davvisámegiella • Deutsch • Eesti • Ελληνικά • Español • Esperanto • Euskara • فارسی • Français • Frysk • Gaeilge • Galego • ГӀалгӀай • 한국어 • Հայերեն • हिन्दी • Hrvatski • Ido • Bahasa Indonesia • IsiXhosa • IsiZulu • Íslenska • Italiano • עברית • Jawa • ಕನ್ನಡ • ქართული • Қазақша • Kiswahili • Kreyòl ayisyen • Kriyòl gwiyannen • Kurdî • Кыргызча • Ladin • ລາວ • Latina • Latviešu • Lietuvių • Magyar • Македонски • മലയാളം • მარგალური • مصرى • Bahasa Melayu • 閩東語 / Mìng-dĕ̤ng-ngṳ̄ • Монгол • မြန်မာဘာသာ • Nederlands • नेपाली • 日本語 • Nordfriisk • Norsk bokmål • Norsk nynorsk • Occitan • Oromoo • Oʻzbekcha / ўзбекча • ਪੰਜਾਬੀ • پنجابی • پښتو • Patois • Polski • Português • Română • Runa Simi • Русский • Саха тыла • Scots • Shqip • Sicilianu • සිංහල • Simple English • سنڌي • Slovenčina • Slovenščina • Soomaaliga • Српски / srpski • Srpskohrvatski / српскохрватски • Suomi • Svenska • Tagalog • தமிழ் • తెలుగు • ไทย • Тоҷикӣ • ᏣᎳᎩ • Türkçe • Українська • اردو • Vahcuengh • Tiếng Việt • 文言 • Winaray • 吴语 • ייִדיש • 粵語 • 中文 A gene is a region of In gene (from γένος, generation birth gender) can have several different meanings. The Mendelian gene is a basic unit of During The transmission of genes to an organism's A gene can acquire The term gene was introduced by Danish botanist, ...

Researchers have found a number of genes that are linked to Alzheimer's disease. Some genes increase the likelihood of getting the disease, called risk genes. Others ensure getting the disease, called deterministic genes. Deterministic genes are rare. However, genes are just part of what's involved in getting Alzheimer's disease. • APOE e2. This is the least common. It reduces the risk of Alzheimer's. • APOE e4. This gene is a little more common. It increases the risk of Alzheimer's. And it's linked to getting a worse form of the disease. • APOE e3. This most common gene doesn't seem to affect the risk of Alzheimer's. Genes aren't the only factor One copy of the APOE gene comes from the mother and another from the father. Having at least one APOE e4 gene doubles or triples the risk of getting Alzheimer's disease. Some people have two APOE e4 genes, one from each parent. Having two genes increases the risk of getting Alzheimer's disease even more, about eight- to twelvefold. But not everyone who has one or even two APOE e4 genes gets Alzheimer's disease. And many people who don't have an APOE e4 gene get the disease. That suggests that the APOE e4 gene increases risk but is not a cause. There's likely more to getting Alzheimer's disease than just genes, such as lifestyle, race, ethnicity and environment. Other late-onset genes As gene research goes on, researchers are finding links between late-onset Alzheimer's and a number of other genes. Examples include: • ABCA7. This g...

• A gene is a small section of • The purpose of • Each gene contains the information required to build specific proteins needed in an organism. • The human • Genes come in different forms, called • In humans, alleles of particular genes come in pairs, one on each • An individual’s • For example, for a gene that determines eye colour there may be several different alleles. One allele may result in blue eyes, while another might result in brown eyes. The final colour of the individual’s eyes will depend on which alleles they have and how they interact. • The characteristic associated with a certain allele can sometimes be

Somatic gene therapy: Somatic gene therapy aims to correct a defect in the DNA of a somatic cell or to provide an RNA molecule to treat or prevent a genetic disease in the person who is undergoing the therapy. This treatment may be used if you have an inherited mutation or if the mutation developed due to environmental factors. Some research using gene augmentation therapy involves the insertion of a healthy DNA molecule or an RNA sequence into a cell, but not into the DNA of the recipient. This has been shown in experimental studies to trigger the production of healthy proteins, but future copies of the cell are not expected to contain the healthy gene. • Cystic fibrosis: An inherited disorder in which thick mucus is produced, clogging the airways and blocking the secretion of digestive enzymes • Sickle cell disease: An inherited disorder that results in abnormal hemoglobin production (the protein that carries oxygen in the red blood cells) • Leber's hereditary optic neuropathy (LHON): An inherited disorder that causes the death of cells in the • Inherited or acquired retinal disease: Conditions that damage to the • WW domain-containing oxidoreductase (WWOX) epileptic encephalopathy syndrome: A genetic condition resulting in severe epilepsy, developmental delays, and early death • Spinocerebellar ataxia and autosomal recessive 12 (SCAR12): An inherited disorder resulting in seizures in infancy, developmental delays, and inability to coordinate movement • Cancer: Many type...