Aceclofenac tablet uses

Aceclofenac tablet Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs) Aceclofenac tablet is a NSAID that inhibits both isoforms of COX enzyme, a key enzyme involved in the inflammatory cascade. COX-1 enzyme is a constitutive enzyme involved in prostacyclin production and protective functions of gastric mucosa whereas COX-2 is an inducible enzyme involved in the production of inflammatory mediators in response to inflammatory stimuli. Aceclofenac tablet displays more selectivity towards COX-2 (IC50 of 0.77uM) than COX-1 (IC50 of >100uM), which promotes its gastric tolerance compared to other NSAIDs. The primary metabolite, 4'-hydroxyaceclofenac, also minimally inhibits COX-2 with IC50 value of 36uM . Although the mode of action of aceclofenac is thought to mainly arise from the inhibition of synthesis of prostaglandins (PGE2), aceclofenac also inhibits the production of inflammatory cytokines, interleukins (IL-1β, IL-6), and tumor necrosis factors (TNF) . It is also reported that aceclofenac also affects the cell adhesion molecules from neutrophils [A19763]. Aceclofenac tablet also targets the synthesis of glycosaminoglycan and mediates chrondroprotective effects . Uses Aceclofenac tablet is used for the relief of pain and inflammation in both acute and chronic pain like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, gynaecological pain etc. Aceclofenac...

Identification Generic Name Aceclofenac DrugBank Accession Number DB06736 Background Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies Type Small Molecule Groups Approved, Investigational Structure Close Weight Average: 354.18 Monoisotopic: 353.0221633 Chemical Formula C 16H 13Cl 2NO 4 Synonyms • 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester • 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid • 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid • Aceclofenac • Acéclofénac Learn more Pharmacodynamics Aceclofenac is a NSAID that inhibits both isoforms of COX enzyme, a key enzyme involved in the inflammatory cascade. COX-1 enzyme is a constitutive enzyme involved in prostacyclin production and protective functions of gastric mucosa whereas COX-2 is an inducible enzyme involved in the production of inflammatory mediators in response to inflammatory stimuli. Aceclofenac displays more selectivity towards COX-2 (IC50 of 0.77uM) than COX-1 (IC50 of >100uM), which promotes its gastric tolerance compared to other NSAIDs. The primary metabolite, 4'-hydroxyaceclofenac, also minimally inhibits COX-2 with IC50 value of 36uM Mechanism of action Through COX-2 inhibition, ace...

Aceclofenac + Thiocolchicoside is a combination of two medicines: Aceclofenac and Thiocolchicoside, which relieves pain and relaxes the muscles. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles. • Aceclofenac + Thiocolchicoside helps relieve pain and muscle spasm that may occur due to strains, sprains, and muscle injuries. • It is usually used along with rest and physical therapy. • Take it with food to avoid an upset stomach. • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. • Avoid consuming alcohol when taking Aceclofenac + Thiocolchicoside as it may cause excessive drowsiness. Q. What is Aceclofenac+Thiocolchicoside? Aceclofenac+Thiocolchicoside is a combination of two medicines: Aceclofenac and Thiocolchicoside. This medication helps in relieving muscle pain. It relaxes the muscles by acting on the central nervous system and lowering chemical substance in the body that cause pain and inflammation. Q. Is it safe to use Aceclofenac+Thiocolchicoside? Yes, Aceclofenac+Thiocolchicoside is safe for most of the patients. However, in some patients it may cause some common unwanted side effects like nausea, vom...

Aceclofenac Tablet Uses, Combinations, Side-Effects. Aceclofenac Tablet is used to relieve pain in the conditions like Osteoarthritis, Rheumatoid Arthritis, and Ankylosing Spondylitis. Medicine Aceclofenac 100 g tabletalso used to treat the symptoms of fever, muscle pain, pain related to mensturation, dental and operation. • Gout • • Headache • Muscle pain • Dental pain • Post-operative pain • Pain during menstruation • Osteoarthritis • Rheumatoid arthritis • Ankylosing spondylitis Read also: Migraine vs. Headache, causes and treatment How Aceclofenac 100 MG Tablet Works in the body? It is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation, redness and swelling. Aceclofenac Tablet – combination, active content composition and active ingredients Tablet contains Aceclofenac and Paracetamol as active ingredients. Aceclofenac Tablet Side Effects • Abdominal pain • Constipation • • Epigastric pain • Skin rash • • Nausea • Indigestion Read also: Constipation treatment, causes and symptoms How to Use/take Aceclofenac 100 MG Tablet Consult with the doctor before using tablet. Inform your doctor about your current list of medications. Aceclofenac medicine Substitutes • Acemiz 100 MG Tablet • Aceroc 100 MG Tablet • Hifenac 100 MG Tablet • Movon 100 MG Tablet • Niplonac 100 MG Tablet Drug Interaction of Aceclofenac 100 MG Tablet Drinking alcohol with this medicine substantially increa...

Aceclofenac is a non steroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It works by blocking the production of certain chemicals in the body that cause pain and inflammation. Aceclofenac tablets are available in various strengths, typically ranging from 50mg to 200mg. The usual adult dose is 100mg twice daily, taken with food. Aceclofenac Tablet Uses Aceclofenac tablets are used to relieve pain and inflammation associated with various conditions, including: Rheumatoid arthritis: A chronic inflammatory disorder that affects the joints. Osteoarthritis: a degenerative joint disease that commonly affects the knees, hips, and hands. Ankylosing spondylitis: a type of arthritis that primarily affects the spine, causing pain and stiffness. Musculoskeletal disorders: conditions that affect the muscles, bones, and joints, such as tendonitis, bursitis, and gout. Acute pain: such as back pain, dental pain, menstrual cramps, and postoperative pain. How Does Aceclofenac Work in the Body Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain chemicals in the body called prostaglandins. Prostaglandins are involved in causing pain, inflammation, and fever in the body. Aceclofenac inhibits the activity of the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. By blocking the COX enzy...

What Is Clanza CR? Clanza CR (aceclofenac tablet, film coated) is a nonsteroidal anti-inflammatory drug (NSAID) indicated for rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and periarthritis of scapulohumerous, lumbago, ischiadynia, and pain caused by nonaticular rheumatism. What Are Side Effects of Clanza CR? Side effects of Clanza CR include: • gastrointestinal disorders (indigestion/heartburn, abdominal pain, nausea), • rash, • redness, • hives, • symptoms of bedwetting, • headache, • dizziness, and • drowsiness Dosage for Clanza CR The recommended adult dose of Clanza CR is 200 mg daily, taken as one dose (every 24 hours). Clanza CR In Children The dosage and indication of Clanza CR is not established yet for children with less than 6 years old. What Drugs, Substances, or Supplements Interact with Clanza CR? Clanza CR may interact with other medicines such as: • lithium, • digoxin, • oral antidiabetic agents, • anticoagulants, • diuretics, and • other analgesics Tell your doctor all medications and supplements you use. Clanza CR During Pregnancy and Breastfeeding Since there is no information on the safe use of Clanza CR during pregnancy and lactation, the use of Clanza CR should be avoided during pregnancy and while breastfeeding. Additional Information Our Clanza CR (aceclofenac tablet, film coated) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not ...

( 1) Aceclofenac and paracetamol are two pain-relieving medication which are often comes in one package. These tablets treat various conditions that cause pain, including headaches, dental pain, and muscle aches. Further, aceclofenac and Paracetamol are both non-steroidal anti-inflammatory drugs (NSAIDs), which means they work by reducing inflammation and swelling. You will learn more about aceclofenac and paracetamol tablet uses and their benefits. The tablets are effective and you can tolerate them if they cause any side effects. It is essential to know the potential side effects and precautions with their uses. This blog will take a closer look at the uses, side effects, and precautions of aceclofenac and paracetamol tablets. Table of Contents • 1 Aceclofenac and Paracetamol Tablet • 1.1 Aceclofenac and Paracetamol Tablet Uses • 1.2 Side Effects • 1.3 Benefits • 1.4 Price of Aceclofenac and Paracetamol Tablet in India • 1.5 Precautions • 1.6 Conclusion • 1.7 Frequently Asked Questions related to Aceclofenac and Paracetamol Tablet • 1.7.1 Q1. Why do people take Aceclofenac and Paracetamol Tablets? • 1.7.2 Q2. How Aceclofenac and Paracetamol Tablet works? • 1.7.3 Q3. What are the side effects of Aceclofenac and Paracetamol Tablet? • 1.7.4 Q4. What is the application of the tablet? Aceclofenac and Paracetamol Tablet Aceclofenac and paracetamol tablets are products helps to treat mild to moderate pain. These tablets effectively reduce pain associated with sprains, strains, ...