Acute glomerulonephritis

Acute Glomerulonephritis Acute glomerulonephritis (AGN) is kidney disease characterized by proliferation and inflammation of the glomeruli. From: Pediatric Clinical Advisor (Second Edition), 2007 Related terms: • Proteinuria • Rheumatic Fever • Acute Kidney Injury • Microhematuria • Therapeutic Procedure • Patient • Inpatient Stanford T. Shulman, ... Robert R. Tanz, in Principles and Practice of Pediatric Infectious Diseases (Sixth Edition), 2023 Epidemiology PSAGN (“Bright disease”) was described by Richard Bright in 1836 as hematuria after scarlet fever. Unlike ARF, PSAGN occurs as a consequence of either GAS pharyngitis or pyoderma. PSAGN is primarily a disease of preschool and school-aged children; approximately 60% of patients are between 2 and 12 years of age. The exact incidence of PSAGN is difficult to determine because many cases are asymptomatic; however, PSAGN is the most common form of acute glomerulonephritis and acute renal insufficiency in children. Certain M types of GAS associated with pharyngitis (e.g., M1, M2, M3, M4, M12, and M15), in addition to certain M types associated with pyoderma (e.g., M49, M52, M55, M59, M60, and M61), are commonly associated with PSAGN and are considered nephritogenic. 79 Although PSAGN most often is a sporadic disease, it also can occur in epidemic forms. Concomitant presence of ARF and PSAGN is unusual in a population and very rare in a patient. John R. Sedor, in Nephrology Secrets (Fourth Edition), 2019 1. What is the syndr...