Carbimazole

This page has been archived. It has not been updated since 26/04/2018. External links and references may no longer work. Antithyroid medicines are used to treat an overactive thyroid gland (hyperthyroidism). Carbimazole is the most commonly used. You may require careful monitoring to get the right levels of these medicines for you. Most of the side-effects experienced are minor. However, when taking an antithyroid medicine, if you develop any of the side-effects (listed below) or any other signs of infection, you must stop the medicine and report this to your doctor immediately. An overactive thyroid is potentially serious and you should see a legitimate doctor before seeking help from herbal or homeopathic remedies. Antithyroid Medicines In this article • What are antithyroid medicines for hyperthyroidism? • Are there different types of antithyroid medication for hyperthyroidism? • How does antithyroid medication work? • Which is the best treatment for an overactive thyroid gland? • How do I take antithyroid medicine? • How quickly does antithyroid medication work? • How long is treatment needed for an overactive thyroid gland? • Will hyperthyroidism return after treatment with antithyroid medicines? • What would happen if I didn't take antithyroid medicines? • What are the possible side-effects of antithyroid medication? • Can I buy antithyroid medicines or do I need a prescription? • Who can and cannot take antithyroid medicines? • Are there homeopathy treatments for ov...

Medical uses Medical therapy for hyperthyroidism typically involves either titrating the dose of carbimazole until the patient becomes euthyroid or maintaining a high dose of carbimazole to suppress endogenous thyroid production, and then replacing thyroid hormone with levothyroxine ("block and replace"). Treatment is usually given for 18–24 months followed by a trial withdraw. The onset of anti-thyroid effect is rapid but the onset of clinical effects on thyroid hormone levels in the blood is much slower. This is because the large store of pre-formed T 3 and T 4 in the thyroid gland and bound to Adverse effects Whilst Its most serious rare side effect is Precautions Some people are allergic to [ verification needed] Carbimazole should be used judiciously in pregnancy as it crosses the placenta. It has (rarely) been associated with congenital defects, including For the above reasons, it is preferable to use • Therapeutic Goods Administration (TGA). 12 May 2022 . Retrieved 13 May 2022. • World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. • Lawrence N, Cheetham T, Elder C (September 2019). (PDF). Clinical Endocrinology. 3 (91): 417–423. • Kragie L, Turner SD, Patten CJ, Crespi CL, Stresser DM (August 2002). "Assessing pregnancy risks of azole antifungals using a high throughput aromatase inhibition assay". Endocrine Research. 28 (3): 129–40. • Brunton L, Chabner BA, Knollman B (2011). Goodman & Gilman's pharmacol...

Carbimazole is used to treat an overactive thyroid gland (hyperthyroidism). Keep your regular appointments with your doctor so that your condition can be monitored and any dose adjustments can be made. You will need to have regular blood tests. Common side-effects tend to be minor but, on occasions, carbimazole can cause serious blood disorders. If you get an infection, a sore throat, mouth ulcers, a high temperature (fever), or any unusual bruising, or if you just feel generally unwell, contact your doctor for advice straightaway. Type of medicine Antithyroid medicine Used for Hyperthyroidism Available as Tablets Antithyroid medicines like carbimazole are used to treat an Carbimazole may be used alone or together with other treatments for hyperthyroidism. It is also a treatment used to prepare a person for surgical removal of part or all of the thyroid gland (thyroidectomy), and before radio-iodine treatment. Before taking carbimazole Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking carbimazole it is important that your doctor or pharmacist knows: • If you are pregnant, trying for a baby, or breastfeeding. • If you have been told you have a blood or bone-marrow disorder. • If you have any problems with the way your liver works. • If you have ever suffered from an inflamed pancreas (acute pancreatitis). • If you are taking any other medicines. Thi...

Initial dose: 15mg to 60mg daily in two or three divided doses. Continue this dose until the patient becomes euthyroid, usually after 4 to 8 weeks. Subsequent therapy may be administered in one of two ways: Maintenance regimen: Maintenance dose: 5mg to 15mg daily. Continue therapy for at least six months, up to eighteen months maximum. Blocking-replacement regimen: Maintenance dose: 20mg to 60mg daily. Supplemental levothyroxine is given concurrently at a dose of 50micrograms to 150micrograms daily, to prevent hypothyroidism. Continue therapy for at least six months, up to eighteen months maximum. Initial dose: 15mg daily until euthyroid, then adjust as necessary. Higher doses may be required, particularly in thyrotoxic crisis. The following alternative dosing schedule may be suitable: Children aged 12 years to 18 years 30mg in single or divided doses until euthyroid, then gradually reduce to a maintenance dose of 30% to 60% of the initial dose. Children aged 1 month to 12 years 750 micrograms per kg (maximum dose 30mg) daily in single or divided doses until euthyroid, then gradually reduce to a maintenance dose of 30% to 60% of initial dose. Precautions and Warnings Females of childbearing potential Breastfeeding Glucose-galactose malabsorption syndrome Lactose intolerance Mild hepatic impairment Pregnancy Retrosternal goitre Discontinue treatment temporarily at time of administration of radio-iodine Contains lactose Monitor creatine kinase levels in patients reporting my...

• • • • • • • • • What is carbimazole? It comes as 5mg, 10mg, 15mg and 20mg tablets. What is carbimazole used for? • Carbimazole is used to treat people with an overactive thyroid gland, also known as For some people, taking carbimazole for several months may be enough to return thyroid function to normal. For others, carbimazole is used to lower the amount of thyroid hormones in the body in preparation for treatment with radioactive iodine, or surgery to remove all or part of the thyroid gland (thyroidectomy). 💡Key facts • Carbimazole treatment is suitable for adults and children. • Women should use effective contraception to avoid getting pregnant while taking carbimazole. • You may need to take a dose once, twice or three times a day. Always follow your doctors instructions. • During treatment you'll need to have regular • The most common side effects are feeling sick, upset stomach, headache, joint pain, skin rash and itching. • On rare occasions carbimazole can cause problems with your blood cells, so you need to tell your doctor immediately if you develop a sore throat, mouth ulcers, bruising, fever or feel generally unwell. • Do not • It's usually fine to drink alcohol while you're taking carbimazole. 9 sneaky symptoms of thyroid problems How does carbimazole work? The thyroid gland uses a chemical called iodine to make thyroid hormones (T3 and T4). Iodine must be converted to a usable form in the body before the thyroid gland can combine it with other components to...

PACKAGE LEAFLET: INFORMATION FOR THE USER CARBIMAZOLE 5MG TABLETS Carbimazole Tablets are available in two strengths: 5mg and 20mg. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you:  Keep this leaflet. You may need to read it again.  If you have any further questions, ask your doctor or pharmacist.  This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.  If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4. What is in this leaflet: 1. What Carbimazole is and what it is used for 2. What you need to know before you take Carbimazole 3. How to take Carbimazole 4. Possible side effects 5. How to store Carbimazole 6. Contents of the pack and other information 1. WHAT CARBIMAZOLE IS AND WHAT IT IS USED FOR The name of your medicine is Carbimazole 5 mg tablets or Carbimazole 20 mg tablets (called Carbimazole in this leaflet). This belongs to a group of medicines called 'anti-thyroid' medicines. Carbimazole is used for adults and children with an overactive thyroid gland (called 'hyper-thyroidism').  It works by reducing the amount of thyroid hormones made in your thyroid gland  It can be used on its own, or with other treatments for an over-active thyroid gland  It can also be used before part of the thyroid gland has been removed...

• Carbimazole is used for the treatment of hyperthyroidism. • You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid. • It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. • Stop taking Carbimazole and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin. • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding. Q. Can I just stop taking Carbimazole? No, you should not stop taking Carbimazole even if you start feeling better. You may have to take it for several months depending on your investigations. The duration of the treatment will continue till the thyroid hormone levels return to normal. This duration may vary from six months to 18 months. Your doctor will decide when the treatment should be stopped. Q. My sister is taking Carbimazole for overactive thyroid gland. She frequently gets sore throat and stops and restarts the treatment again and again. Is there any risk if she continues to take Carbimazole when she has sore throat? Very rarely, Carbimazole interferes with the bone marrow and causes a drastic drop in white blood cells. These white blood cells are a part of the body's defense against bacterial infections, such as sore throats. So, ...

Carbimazole is a medicine used to treat an Your thyroid controls things like your heart rate and body temperature. When it makes too many hormones, you can have symptoms such as weight loss, mood swings and feeling irritable. Carbimazole helps to ease these symptoms by reducing the amount of hormones your thyroid produces. This medicine is only available on prescription. It usually comes as tablets. If you are unable to swallow tablets, your doctor may be able to prescribe carbimazole as a liquid. Sometimes your doctor will prescribe carbimazole together with a 2. Key facts • You’ll have blood tests before and during treatment with carbimazole. • When you first start taking this medicine, it can take up to 3 weeks to see an improvement in your symptoms. • Side effects usually only happen in the first 8 weeks and tend not to last long. • One rare side effect can be a sudden drop in your white blood cell count. This makes it harder to fight infections. • If you are pregnant, your dose of carbimazole needs to be monitored carefully. 3. Who can and cannot take carbimazole Most adults, children and babies can take carbimazole. However, carbimazole is not suitable for everyone. To make sure it's safe for you, tell your doctor if you: • have ever had an allergic reaction to carbimazole or any other medicines • have had severe pancreas problems ( • are due to have radioactive iodine treatment for your • have liver problems or a problem with your blood • have a swollen thyroid ( • ...