Ciprofloxacin

Ciprofloxacin is a • • • • abdominal infections in adults, when used in combination with • • joint and bone infections in adults • • • • • Ciprofloxacin is also approved to help prevent infections from inhaled For more information, see the “ Drug details Ciprofloxacin (also called ciprofloxacin hydrochloride) belongs to a class of drugs called fluoroquinolone Ciprofloxacin comes as an oral tablet in 100-milligram (mg), 250-mg, 500-mg, and 750-mg strengths. The drug also comes in other forms, but this article does not cover them. These include Brand-name versions Ciprofloxacin oral tablet is the generic version of the brand-name drug The other forms of ciprofloxacin have different brand-name drug versions. For information on those versions, talk with your doctor or pharmacist. Ciprofloxacin is a generic drug. A generic drug is an exact copy of the active drug in a brand-name medication. Cipro is the brand-name medication that ciprofloxacin is based on. A generic is considered to be as safe and effective as the original drug. Generics tend to cost less than brand-name drugs. If you’re interested in using Cipro instead of ciprofloxacin, talk with your doctor. They can tell you if Cipro comes in forms and strengths suitable for your condition. If you have insurance, you’ll also need to check whether your plan will cover Cipro. To learn more about how generics compare with brand-name drugs, see The Food and Drug Administration (FDA) approves prescription drugs such as ciproflox...

What Is Ciprofloxacin and How Does It Work? This Ciprofloxacin is available under the following different brand names: Susceptible organisms • Aeromonas hydrophila, Bacillus anthracis, Bacteroides fragilis, Campylobacter jejuni, Citrobacter freundii, Citrobacter diversus, Enterobacter cloacae, Enterococcus faecalis, Escherichia coli, Haemophilus ducreyi, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Legionella pneumophila, Morganella morganii, Moraxella catarrhalis, certain mycobacteria, Neisseria gonorrhoeae, Proteus mirabilis, Providencia spp, Pseudomonas aeruginosa, • First-line therapy: B anthracis, C freundii, C jejuni, Enterobacter spp, Hafnia alvei, S typhi, Salmonella spp, Shigella spp; no unanimity on others (e.g., K pneumoniae, M morganii, V cholerae, Y enterocolitica) What Are the Dosages of Ciprofloxacin? Dosage of Ciprofloxacin: Adult and Pediatric Dosage Forms and Strengths Infusion solution • 200 mg/100mL • 200 mg/20mL • 400 mg/40mL • 400 mg/200mL Oral suspension • 250 mg/5mL • 500 mg/5mL Tablet • 100 mg (adult only) • 250 mg • 500 mg • 750 mg Tablet, extended-release • 500 mg • 1000 mg Dosage Considerations– Should be Given as Follows: Acute • Mild/moderate: 500 mg orally every 12 hours or 400 mg intravenously (IV) every 12 hours for 10 days • Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for acute sinusitis Bone and Joint Infections • Mild/moderate: 500 mg orally eve...

This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions. This medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take one dose a day, try to take it at the same time each day. If you need to take this medicine for anthrax infection, your doctor will want you to begin using it as soon as possible after you are exposed to anthrax. You may swallow the Cipro® tablet whole or break it in half at the score line. Do not crush or chew it. Tell your doctor if you have trouble swallowing the tablet. Swallow the extended-release tablet whole. Do not crush, split, or chew it. Shake the oral liquid for at least 15 seconds just before each use. The oral liquid has small microcapsules floating in it. These microcapsules may look like bubbles or small beads. Do not chew the microcapsules when you take the oral liquid. Measure the oral liquid with the marked measuring spoon that comes with the bottle. You may take this medicine with or without food. However, Proquin® XR tablets should be taken with a main meal, preferably the evening meal. Drink plenty of fluids while you are using this medicine. Drinking extra water will help prevent some unwanted effects of ciprofloxacin. Do not take this medicine alone with milk, yogurt, or other dair...

Precautions Drug information provided by: It is very important that your doctor check your or your child's progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it. Blood and urine tests may be needed to check for unwanted effects. If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor. Do not use this medicine if you are also taking tizanidine (Zanaflex®). Tell your doctor if you or your child are also using theophylline (Theo-Dur®) or other products that contain caffeine (eg, coffee, soda, chocolate). Using these medicines together may increase the risk for more serious side effects. Ciprofloxacin may rarely cause inflammation (tendinitis) or tearing of a tendon (the cord that attaches muscles to bones). This can occur while you are taking the medicine or after you finish taking it. The risk of having tendon problems may be increased if you are over 60 years of age, are using steroid medicines (eg, dexamethasone, prednisolone, prednisone, Medrol®), have severe kidney problems, have a history of tendon problems (eg, rheumatoid arthritis), or if you have received an organ transplant (eg, heart, kidney, or lung). Check with your doctor right away if you have sudden pain or swelling in a tendon after exercise (eg, ankle, back of the knee or leg, shoulder, elbow, or wrist), bruise more easily after an injury, or a...