Creatinine clearance calculator

Equations for Estimating Creatinine Clearance or GFR • • • • • • Considerations and Variations of Creatinine Clearance • CrCl) versus Glomerular Filtration Rate ( GFR) • • • • • • • • 1 Particularly for renally dosing medications, the Cockcroft-Gault equation has been the long-standing gold standard for the estimation of creatinine clearance for decades. The original study was based on data from 249 male patients with stable renal function. The study used actual body weight, but mentioned that a correction factor of some kind should be used in patients with marked obesity or ascites. $$ \\ CrCl =\frac *0.85\;(if\;female) $$ CKD-EPI 2 The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation was developed as a follow-up to the GFR (less than 60 mL/min/1.73 m 2), but more accurate at a higher GFR. The CKD-EPI equation was developed and validated retrospectively in 8,254 patients from 10 studies. The study included all patients age > 20 years old who were not pregnant and did not have renal failure (defined as an e GFR< 15 mL/min/1.73 m 2). The data set included 45% women and 87% non-black patients. $$ \\ GFR\;(mL/min/1.73 m^2) =\\ Black\;females,\;SCr\;\le\;0.7\;mg/dL:\\ 166 * (SCr/0.7)^ $$ 3 DEPRECATED Published as a "Letter to the Editor", the Jelliffe equation does not require a patient's height or weight because it describes renal function normalized to a body surface area of 1.73 m 2. While this was a landmark equation for its era, its use has become depr...

Creatinine Clearance Calculator (CrCL) Check out the Advanced Multi-clearance Calculator Creatinine Clearance Calculator Patient Name: Location: Age: Scr: Sex: Select serum creatinine reference standard: [ Height: Weight: Is the serum creatinine (Scr) currently stable: Restrict the maximum calculated clearance to this value: Creatinine Clearance methods Cockcroft and Gault equation utilizing the tbw (Total body weight) to calculate an estimated CrCL Cockcroft and Gault equation: CrCl = [(140 - age) x TBW] / (Scr x 72) (x 0.85 for females) Cockcroft and Gault equation utilizing the ibw (Ideal body weight) to calculate an estimated creatinine clearance Cockcroft and Gault equation: CrCl = [(140 - age) x IBW] / (Scr x 72) (x 0.85 for females) Note: if the ABW (actual body weight) is less than the IBW use the actual body weight for calculating the CRCL. Estimate Ideal body weight in (kg) Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet. Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet. Cockcroft and Gault equation utilizing the adjusted body weight to calculate an estimated creatinine clearance. CrCl = [(140 - age) x AjBW] / (Scr x 72) Note: (Multiply result by 0.85 for females) AjBW = adjusted body weight: AjBW = IBW + 0.4( ABW - IBW) Estimated IBW: Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet. Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet. Some studies have shown that utilizing the adjusted body weight improves accuracy compared to other co...