Dostarlimab

• Chemical and physical data C 6420 H 9832 N 1690 O 2014 S 44 144 325.73g·mol −1 Dostarlimab, sold under the brand name Jemperli, is a The most common side effects reported in the US include Dostarlimab was approved for the treatment of endometrial cancer in both the United States and the European Union in April 2021. Based on the Garnet trial, dostarlimab gained accelerated approval from the US Medical uses [ ] In the United States, dostarlimab is In the European Union, dostarlimab is indicated as In August 2021, the US Endometrial cancer [ ] Endometrial cancer (EC) is a disease where cancerous cells reside in the lining of the Solid tumors [ ] Solid tumors are tumors that do not contain any liquid or Side effects [ ] Serious adverse reactions in >2% of patients included Immune-mediated adverse reactions can occur including The most common side effects reported while taking this medication during a trial were Symptoms of overdose are similar to the side effect profile of the medication, so it could involve significant Immune-mediated adverse reactions [ ] Dostarlimab is a monoclonal antibody that binds to PD-1 to block it from binding PD-1 ligands to remove inhibition of immune response. Examples of immune-mediated adverse reactions include immune-mediated Pregnancy and lactation [ ] Dostarlimab can cause harm to a fetus. Data is not available regarding the presence of dostarlimab in breastmilk. Hepatotoxicity [ ] Dostarlimab causes mild to moderate elevations to serum am...

What is dostarlimab? Dostarlimab is used to treat adults with certain cancers after other treatments did not work or stopped working, and/or the Your doctor will make sure you have the correct tumor type to be treated with dostarlimab. Dostarlimab may also be used for purposes not listed in this medication guide. Before taking this medicine Tell your doctor if you have ever had: • breathing problems; or • immune system problems. May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use Do not breastfeed while using dostarlimab, and for at least 4 months after your last dose. Dostarlimab side effects Get emergency medical help if you have signs of an allergic reaction ( or a severe skin reaction ( Some side effects may occur during the injection. Tell your caregiver if you feel light-headed, chilled or feverish, itchy, or short of breath. Dostarlimab strengthens your immune system to help it attack cancer cells, but it may also attack healthy cells and you could develop serious or fatal side effects. Dostarlimab may cause serious side effects. Call your doctor at once if you have: • new or worsening cough, shortness of breath; • chest pain, irregular heartbeats; • a light-headed feeling, like you might pass out; • a seizure; • confusion, hallucinations, eye pain or redness, vision problems; • severe stomach pain, • low red blood cells ( • low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough; • kidney problems--s...