Background. Dostarlimab is an immune-checkpoint inhibitor that targets the programmed cell death 1 receptor. The combination of chemotherapy and immunotherapy may have synergistic effects in the.

Jemperli (dostarlimab) is a member of the anti-PD-1 monoclonal antibodies drug class and is commonly used for Endometrial Cancer, and Solid Tumors. The cost for Jemperli intravenous solution (gxly 500 mg/10 mL) is around $11,540 for a supply of 10 milliliters, depending on the pharmacy you visit.

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MSK researchers conducted a prospective study in which single agent dostarlimab, an anti-PD-1 monoclonal antibody, was administered every three weeks for six months in patients with mismatch repair-deficient stage 2 and 3 rectal adenocarcinoma, to be followed by standard chemoradiation and surgery.