Iodoform formula

Identification Generic Name Iodoform DrugBank Accession Number DB13813 Background Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions Type Small Molecule Groups Approved, Experimental, Vet approved Structure Learn more Pharmacodynamics Iodoform exhibits antibacterial activities after topical application. In a comparative study of wound dressing agents, iodoform gauze exerted an antibacterial effect 3 hours after the start of bacterial growth of E. coli and subsequently maintained the strong antibacterial effectiveness in vitro, while cell proliferation was enhanced at low concentrations of iodoform Mechanism of action While the mechanism of action of iodoform remains unclear, it is proposed that iodoform releases iodine, which denatures bacterial proteins by oxidation of the free iodine in vitro, high concentrations of iodoform was shown to decrease the viability of macrophages and epithelial cells and reduced the secretion of P. gingivalis-induced TNFα Absorption Iodoform is reported to be absorbed through denuded skin, wounds or mucous membranes Volume of distribution No pharmacokinetic data available. Protein binding No pharmacokinetic data available. Metabolism It is expected to be oxidized to iodine Hover over products below to view reaction partners • Iodoform • Learn more Toxicity Oral LD50, dermal LD50, and inhalation LC...

\( \newcommand\) • • • • • This page looks at how the triiodomethane (iodoform) reaction can be used to identify the presence of a CH 3CO group in aldehydes and ketones. There are two apparently quite different mixtures of reagents that can be used to do this reaction. They are, in fact, chemically equivalent. Using iodine and sodium hydroxide solution This is chemically the more obvious method. Iodine solution is added to a small amount of aldehyde or ketone, followed by just enough sodium hydroxide solution to remove the color of the iodine. If nothing happens in the cold, it may be necessary to warm the mixture very gently. A positive result is the appearance of a very pale yellow precipitate of triiodomethane (previously known as iodoform) - CHI 3. Apart from its color, this can be recognised by its faintly "medical" smell. It is used as an antiseptic on the sort of sticky plasters you put on minor cuts, for example. Using potassium iodide and sodium chlorate(I) solutions Sodium chlorate(I) is also known as sodium hypochlorite. Potassium iodide solution is added to a small amount of aldehyde or ketone, followed by sodium chlorate(I) solution. Again, if no precipitate is formed in the cold, it may be necessary to warm the mixture very gently. The positive result is the same pale yellow precipitate as before. The chemistry of the triiodomethane (iodoform) reaction A positive result - the pale yellow precipitate of triiodomethane (iodoform) - is given by an aldehyde or ke...

\( \newcommand\) • • • • • • • • • • • • • • • Beilstein Test The Beilstein test confirms the presence of a halogen in solution, although it does not distinguish between chlorine, bromine, or iodine. A copper wire is dipped into the halogen-containing solution and thrust into a flame. The copper oxide on the wire reacts with the organic halide to produce a copper-halide compound that gives a blue-green color to the flame. Procedure: In the fume hood, clean a looped copper wire by thrusting it into the tip of the blue cone of a Bunsen burner flame until it glows (Figure 6.46a). Be sure to "burn off" any residual liquid on the wire (make sure any green flames from previous tests are gone before you begin). Allow the copper to cool to room temperature, then dip it into a test tube containing 5-10 drops of your sample, coating it as much as possible (Figure 6.46b). If the sample is a solid, adhere some of the solid to the copper wire by first wetting the wire with distilled water then touching it to the solid. Immediately plunge the wire with sample into the blue cone of the flame. A positive result is a green flame, although it might be short-lived and faint (it may be easier to see if the fume hood light is turned off). A negative result is the absence of this green color (Figure 6.46c+d). Figure 6.46: a) Cleaning copper wire in a flame, b) Dipping copper wire into the reagent, c) Negative result (hexanes), d) Positive result (1-chlorobutane). Benedict's Test The Benedict's ...

Idoform Reaction Iodoform that is also known as Triiodomethane is a crystalline yellow chemical that belongs to the organic halogen group. Halogens are any of the 6 nonmetallic elements in Group 17 of the periodic table. Fluorine, chlorine, bromine, iodine, astatine, and Tennessee are the halogen elements. In the year 1822, George Simon Serullas published the first description of iodoform production. Iodine vapour reactions with steam over red hot coals and potassium response with ethanolic iodine in water were responsible for the synthesis’s appearance. Solutions containing acetone, inorganic iodides, and sodium carbonate produces iodoform in electrolysis aqueous. Several chemicals convert iodoform to methylene iodide, a thick liquid that is blue when pure but discoloured by residues of iodine, and is utilised as a heavy medium in gravity separation procedures. In 1880, the antibacterial qualities of iodoform were discovered, and it quickly became a valuable medical tool. However, more effective drugs have now taken its place. What exactly is iodoform? Iodoform is a crystalline yellow chemical that belongs to the organic halogen group. Triiodomethane is another name for it. You might be wondering what a halogen is. Halogens are any of the 6 nonmetallic elements in Group 17 of the periodic table. Fluorine, chlorine, bromine, iodine, astatine, and Tennessee are the halogen elements. The organoiodine substance iodoform has the formula CHl3. It has a deep and unmistakable fra...