Kojic acid

3. Color code: red = O, gray = C, dark blue = Fe, white = H. Deprotonation of the ring-OH group converts kojic acid to kojate. Kojate chelates to iron(III), forming a red complex Fe(HOCH 2C 5OH 2O 2) 3. This kind of reaction may be the basis of the biological function of kojic aicd, that is, to solubilize ferric iron. Being a multifunctional molecule, kojic acid has diverse organic chemistry. The • Bjerrum, J., et al. Stability Constants, Chemical Society, London, 1958. • ^ a b c Bentley, R. (2006). "From miso, sake and shoyu to cosmetics: a century of science for kojic acid". Nat. Prod. Rep. 23 (6): 1046–1062. • Yabuta T (1924). "The constitution of kojic acid, a γ-pyrone derivative formed by Aspergillus oryzae from carbohydrates". 125: 575–587. • Parvez, Shoukat; Kang, Moonkyu; Chung, Hwan-Suck; Cho, Chongwoon; Hong, Moo-Chang; Shin, Min-Kyu; Bae, Hyunsu (2006). "Survey and mechanism of skin depigmenting and lightening agents". Phytotherapy Research. 20 (11): 921–34. • • Nurchi, Valeria M.; Lachowicz, Joanna I.; Crisponi, Guido; Murgia, Sergio; Arca, Massimiliano; Pintus, Anna; Gans, Peter; Niclos-Gutierrez, Juan; Domínguez-Martín, Alicia; Castineiras, Alfonso; Remelli, Maurizio (2011-05-27). "Kojic acid derivatives as powerful chelators for iron(III) and aluminium(III)". Dalton Transactions. 40 (22): 5984–5998. • • Veverka, M., Dubaj, T., Gallovič, J., Jorík, V., Veverková, E., Danihelová, M., & Šimon, P. (2015). Cocrystals of quercetin: synthesis, characterization, and...