Lopramide tab

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Dosage Forms & Strengths liquid • 1mg/5mL • 1mg/7.5mL suspension • 1mg/7.5mL tablet • 2mg capsule • 2mg tablet chewable • 2mg Acute Diarrhea 4 mg initially, then 2 mg after each loose stool; not to exceed 16 mg/day (8 mg/day for self-medication); discontinue if no improvement seen within 48 hours Chronic Diarrhea 4 mg initially, then 2 mg after each loose stool until controlled, and then 4-8 mg/day in divided doses Traveler's Diarrhea 4 mg after first loose stool, then 2 mg after each subsequent stool; not to exceed 8 mg/day Dosage Forms & Strengths liquid • 1mg/5mL • 1mg/7.5mL suspension • 1mg7.5mL tablet • 2mg capsule • 2mg tablet chewable • 2mg Acute Diarrhea First Day of Treatment • 2-6 years (13-20 kg): 1 mg q8hr PO • 6-8 years: (20-30 kg): 2 mg q12hr PO • 8-12 years (>30 kg): 2 mg q8hr PO Second & Subsequent Doses • 0.1 mg/kg PO after each loose stool; not to exceed dose recommended for first 24 hours Chronic Diarrhea 0.08-0.24 mg/kg/day PO divided q12hr Traveler's Diarrhea 12 years: 4 mg after first loose stool, then 2 mg after each subsequent stool; not to exceed 8 mg/day Contraindicated (0) Serious - Use Alternative (37) • amisulpride amisulpride and loperamide both increase QTc interval. Avoid or Use Alternate Drug. ECG monitoring is recommended if coadministered. • anagrelide anagrelide and loperamide both increase QTc interval. Avoid or Use Alternate Drug. • artemether artemether and loperamide both increase QTc interval. Avoid or Use Alternate Drug. • artemeth...

Lopramide 2mg Tablet is used in the treatment of diarrhea. It should not be used in patients with dysentery (diarrhea with blood). Lopramide 2mg Tablet is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are headache, nausea, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Diarrhea can cause water loss and electrolyte imbalance, so drink plenty of fluids to help keep yourself hydrated. It is important to avoid this medicine if you have blood in your stool or if you are severely constipated. • You have been prescribed Lopramide 2mg Tablet for the treatment of diarrhea. • Diarrhea can cause water loss and electrolyte imbalance. Drink plenty of fluids to help keep you hydrated. • Consult your doctor if your diarrhea lasts for more than 48 hours. • Do not use Lopramide 2mg Tablet if you have blood in your sto...

WARNING: TORSADES DE POINTES AND SUDDEN DEATH • Cases of Torsades de Pointes, cardiac arrest, and death have been reported with the use of a higher than recommended dosages of Loperamide hydrochloride capsules (see • Loperamide hydrochloride capsules are contraindicated in pediatric patients less than 2 years of age (see • Avoid Loperamide hydrochloride capsules dosages higher than recommended in adults and pediatric patients 2 years of age and older due to the risk of serious cardiac adverse reactions (see Loperamide Description Loperamide hydrochloride, 4-(p-chlorophenyl)-4-hydroxy-N,N-dimethyl-a,adiphenyl-1-piperidinebutyramide monohydrochloride, is a synthetic antidiarrheal for oral use. The molecular formula for Loperamide hydrochloride, USP is C 29H 33ClN 2O 2HCl, with a molecular weight of 513.50. The structural formula is: Loperamide hydrochloride, USP is available in 2 mg capsules. Loperamide hydrochloride capsules, USP contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, microcrystalline cellulose, magnesium stearate, and sodium starch glycolate. The hard-capsule shell is composed of gelatin, sodium lauryl sulfate, and titanium dioxide. The capsules are printed with black ink composed of black iron oxide, potassium hydroxide, propylene glycol, and shellac. Related/similar drugs Loperamide - Clinical Pharmacology Mechanism of Action In vitro and animal studies show that Loperamide hydrochloride acts by slowing intestinal moti...

Loperamide: 7 things you should know Medically reviewed by • • • • • • • 1. How it works • Loperamide is used to treat diarrhea or loose stools. • Loperamide works on mu-opioid receptors in the gut wall to slow down the movement of the gut. This slows the contractions of the intestine, allowing more water to be absorbed back into the body through the intestinal wall, this makes the stool less watery and decreases the number of bowel movements. Loperamide does not affect the brain and central nervous system. Loperamide also suppresses the gastrocolic reflex and may directly inhibit fluid and electrolyte secretion or stimulate salt and water absorption. • Loperamide belongs to the class of medicines known as antidiarrheals. 2. Upsides • Loperamide is used to treat diarrhea. • Loperamide may also be used in people who have had an ileostomy (a surgical operation where part of the bowel is removed and the cut end diverted to the surface of the abdomen) to reduce the amount of bowel discharge. • Loperamide decreases the number of bowel movements and makes the stool less watery. • Loperamide is long-acting. • Tolerance to the antidiarrheal effect of loperamide has not been observed. • Unlikely to cause drowsiness. • Loperamide is available as a generic. 3. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: • Constipation (this may be a sign that too much loperami...

Loperamide is a medication that comes in a capsule or tablet form. It treats occasional diarrhea by slowing down an overactive bowel. This reduces the number of bowel movements you have. You should only use this medication for a short amount of time. A common brand name of this medication is Imodium A-D®. What is this medication? LOPERAMIDE (loe PER a mide) treats occasional diarrhea. It works by slowing down an overactive bowel, which decreases the number of bowel movements. It belongs to a group of medications called antidiarrheals. It is often used for a short period of time. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Anti-Diarrheal, Imodium A-D, K-Pek II What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • A black or bloody stool • Bacterial food poisoning • Colitis or mucus in your stool • Currently taking an antibiotic medication for an infection • Fever • History of irregular heartbeat • Liver disease • Severe abdominal pain, swelling or bulging • An unusual or allergic reaction to loperamide, other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medication more often than d...

What Is Imodium? Imodium (loperamide hydrochloride) is an antidiarrheal used to treat diarrhea. Imodium is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowel through a surgical opening in the stomach). Imodium is available in generic form and over-the-counter (OTC). What Are Side Effects of Imodium? Imodiummay cause serious side effects including: • diarrhea that is watery or bloody, • stomach pain or bloating, • ongoing or worsening diarrhea, • fast or pounding heartbeats, • fluttering in your chest, • shortness of breath, and • lightheadedness Get medical help right away, if you have any of the symptoms listed above. Common side effects of Imodium include • dizziness, • drowsiness, • tiredness, • constipation, • stomach pain, • skin rash, or • itching. Tell your doctor if you experience serious side effects of Imodium including • severe constipation/nausea/vomiting, • stomach or abdominal pain, or • uncomfortable fullness of the stomach or abdomen. Seek medical care or call 911 at once if you have the following serious side effects: • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out; • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss ...

See also Warning section. If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this Take this medication by If you are taking the chewable tablet, take this medication on an empty If you are using the rapidly dissolving tablets, dry your hands before opening the Tell your doctor if your If you are taking this medication under your doctor's direction for ongoing If your doctor has prescribed this Stop taking this medication and get medical help right away if you have any very serious side effects, including: severe constipation/ A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking If you have any of the following health problems, consult your doctor or pharmacist before using this The rapidly dissolving tablets may contain aspartame or Loperamide may cause a condition that affects the The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using loperamide, tell your doctor or pharmacist of all the drugs you take and if you have any of the fo...

Loperamide: 7 things you should know Medically reviewed by • • • • • • • 1. How it works • Loperamide is used to treat diarrhea or loose stools. • Loperamide works on mu-opioid receptors in the gut wall to slow down the movement of the gut. This slows the contractions of the intestine, allowing more water to be absorbed back into the body through the intestinal wall, this makes the stool less watery and decreases the number of bowel movements. Loperamide does not affect the brain and central nervous system. Loperamide also suppresses the gastrocolic reflex and may directly inhibit fluid and electrolyte secretion or stimulate salt and water absorption. • Loperamide belongs to the class of medicines known as antidiarrheals. 2. Upsides • Loperamide is used to treat diarrhea. • Loperamide may also be used in people who have had an ileostomy (a surgical operation where part of the bowel is removed and the cut end diverted to the surface of the abdomen) to reduce the amount of bowel discharge. • Loperamide decreases the number of bowel movements and makes the stool less watery. • Loperamide is long-acting. • Tolerance to the antidiarrheal effect of loperamide has not been observed. • Unlikely to cause drowsiness. • Loperamide is available as a generic. 3. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: • Constipation (this may be a sign that too much loperami...

WARNING: TORSADES DE POINTES AND SUDDEN DEATH • Cases of Torsades de Pointes, cardiac arrest, and death have been reported with the use of a higher than recommended dosages of Loperamide hydrochloride capsules (see • Loperamide hydrochloride capsules are contraindicated in pediatric patients less than 2 years of age (see • Avoid Loperamide hydrochloride capsules dosages higher than recommended in adults and pediatric patients 2 years of age and older due to the risk of serious cardiac adverse reactions (see Loperamide Description Loperamide hydrochloride, 4-(p-chlorophenyl)-4-hydroxy-N,N-dimethyl-a,adiphenyl-1-piperidinebutyramide monohydrochloride, is a synthetic antidiarrheal for oral use. The molecular formula for Loperamide hydrochloride, USP is C 29H 33ClN 2O 2HCl, with a molecular weight of 513.50. The structural formula is: Loperamide hydrochloride, USP is available in 2 mg capsules. Loperamide hydrochloride capsules, USP contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, microcrystalline cellulose, magnesium stearate, and sodium starch glycolate. The hard-capsule shell is composed of gelatin, sodium lauryl sulfate, and titanium dioxide. The capsules are printed with black ink composed of black iron oxide, potassium hydroxide, propylene glycol, and shellac. Related/similar drugs Loperamide - Clinical Pharmacology Mechanism of Action In vitro and animal studies show that Loperamide hydrochloride acts by slowing intestinal moti...