Mupirocin ointment

Mupirocin is used as a topical treatment for bacterial skin infections (for example, Staphylococcus aureus or Streptococcus pyogenes. It is also useful in the treatment of superficial Staphylococcus aureus (MRSA) infections. Intranasal mupirocin before surgery is effective for prevention of post-operative wound infection with Staphylcoccus aureus and preventative intranasal or catheter-site treatment is effective for reducing the risk of catheter site infection in persons treated with chronic peritoneal dialysis. Resistance Shortly after the clinical use of mupirocin began, strains of Staphylococcus aureus that were S. aureus were isolated. One strain possessed low-level resistance (MuL: IleS). In IleS, a single amino acid mutation was shown to alter mupirocin resistance. MupA. Most strains of Most strains of Pseudomonas fluorescens are also resistant to mupirocin as they produce the antibiotic and it’s possible other species of [ citation needed] The mechanism of action of mupirocin differs from other clinical antibiotics, rendering [ citation needed] A second type of high-level resistant synthetase was discovered in 2012 and termed MupB. It was found in a Canadian Figure 5. MmpB is proposed to synthesize 9-HN with a 3-hydroxy-propionate starter unit and three malonyl-CoA extender units. The domain structure of MmpB is shown below alongside MupE, the proposed enoyl reductase required for complete saturation of 9-HN. ACP= Mupirocin is a mixture of several pseudomonic acids...

This medicine should only be used on the skin. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water. To help clear up your skin infection completely, keep using mupirocin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses. To use: • Wash your hands with soap and water before and after using this medicine. • Apply a thin layer to the affected area of the skin. Rub it in gently. • After applying this medicine, the treated area may be covered with a gauze dressing if desired. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. • For topical dosage form (cream): • For treatment of secondarily infected traumatic skin lesions: • Adults and children 3 months of age and older—Apply three times a day for 10 days. • Children younger than 3 months of age—Use and dose must be determined by your doctor. • For topical ...

Type of medicine An antibacterial skin preparation Used for Bacterial skin infections in adults and children Also called Bactroban® Available as Cream and ointment Mupirocin is an antibacterial cream/ointment which is used to treat small areas of skin infection. It is sometimes used to treat infections such as Mupirocin is used in particular to treat infections caused by bacteria called Staphylococcus aureus (MRSA). Infection with MRSA bacteria mainly occurs in people who are already ill in hospital. The infection can be difficult to treat and it can also spread to other people. There is also a nasal ointment which contains mupirocin. It is prescribed for people who have been in contact with people with MRSA infection. It helps to stop the infection from spreading to other people. See the separate medicine leaflet called Before using mupirocin To make sure that this is the right treatment for you, before you start using mupirocin it is important that your doctor knows: • If you are pregnant or breastfeeding - although mupirocin is not known to be harmful to babies, it is still important that you tell your doctor about this. • If you have a problem with the way your kidneys work. • If you have ever had an allergic reaction to a medicine, or to any skin preparation. How to use mupirocin • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about the preparation prescribed for you. • Wash ...

Bactroban Generic name: myoo-PEER-oh-sin] Drug class: Medically reviewed by • • • • • • • What is Bactroban? Bactroban is an antibiotic that prevents bacteria from growing on your skin. Bactroban topical (for use on the skin) is used to treat skin infections such as Bactroban may also be used for purposes not listed in this medication guide. Warnings Use Bactroban cream or ointment for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed. Avoid your eyes, nose, mouth, and lips when applying Bactroban. If medication gets in any of these areas, wash with water. Watch for signs of improvement in 3 to 5 days. If your condition gets worse or does not improve, see your doctor. A separate formulation, Bactroban nasal ointment, is available for nasal use. Before taking this medicine You should not use Bactroban cream or ointment if you are allergic to mupirocin. To make sure Bactroban is safe for you, tell your doctor if you have ever had: • kidney disease. Do not use Bactroban on a child without medical advice. The cream should not be used on a child younger than 3 months old. The ointment may be used on a child as young as 2 months old. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether mupirocin topical passes into breast milk or if it could harm a...

Read the Patient Information Leaflet if available from your Use this Use this medication regularly to get the most benefit from it. Continue to use it for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection. Avoid using this medication around your Tell your doctor if your condition does not get better in 3 to 5 days. Remember that this Although uncommon, mild burning or stinging after using this medication may occur. If you have severe burning, stinging, or irritation, stop using this medication and tell your doctor right away. This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: If you have these symptoms, do not use anti- Use of this medication for prolonged or repeated periods may result in a new A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking this medicine You should not use mupirocin topical if you are allergic to mupirocin. To make sure mupirocin topical is safe for you, tell your doctor if you have ever had: • kidney disease. Do not use mupirocin topical on a child without medical advice. The cream should not be used on a child younger than 3 months old. The ointment may be used on a child as young as 2 months old. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether mupirocin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. If you apply this medicine to your breast or nipple, wash the areas thoroughly before nursing your baby. How should I use mupirocin topical? Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not take by mouth. Topical medicine is for use only on the skin. If this medicine gets in your eyes, nose, or mouth, rinse with water. Wash your hands before and after applying mupirocin topical. Clean and dry the affected skin area. Use a cotton swab or gauze pad to apply a small amount of mupirocin topical as directed. Do not spread mupirocin topical over large areas of skin. Mupirocin topical is usually applied 3 times per day for 10 days. Use only a small amount of the medicine. Use a sterile gauze pad to cover the treated skin. Do not cover treated areas...

Mupirocin ointment is a medication that treats bacterial skin infections. It prevents bacteria growth and kills existing bacteria on your skin. You can rub this medication on your affected skin. Make sure you wash your hands before and after using the ointment. The brand names of this medication are Bactroban® and Centany®. What is this medication? MUPIROCIN (myoo PEER oh sin) treats skin infections caused by bacteria. It works by killing or preventing the growth of bacteria on the skin. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Bactroban, Centany, Centany AT What should I tell my care team before I take this medication? They need to know if you have any of these conditions: • Kidney disease • Large areas of burned or damaged skin • Stomach or intestine problems such as colitis • An unusual or allergic reaction to mupirocin, other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? This medication is for external use only. Do not take by mouth. Wash your hands before and after use. If you are treating a hand infection, only wash your hands before use. Do not get it in your eyes. If you do, rinse your eyes with plenty of cool tap water. Use it as directed on the prescription label at the same time every day. Do not use it more often than directed. Use the medication for the full course as directed by your...

Before taking this medicine You should not use mupirocin topical if you are allergic to mupirocin. To make sure mupirocin topical is safe for you, tell your doctor if you have ever had: • kidney disease. Do not use mupirocin topical on a child without medical advice. The cream should not be used on a child younger than 3 months old. The ointment may be used on a child as young as 2 months old. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. It is not known whether mupirocin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. If you apply this medicine to your breast or nipple, wash the areas thoroughly before nursing your baby. How should I use mupirocin topical? Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not take by mouth. Topical medicine is for use only on the skin. If this medicine gets in your eyes, nose, or mouth, rinse with water. Wash your hands before and after applying mupirocin topical. Clean and dry the affected skin area. Use a cotton swab or gauze pad to apply a small amount of mupirocin topical as directed. Do not spread mupirocin topical over large areas of skin. Mupirocin topical is usually applied 3 times per day for 10 days. Use only a small amount of the medicine. Use a sterile gauze pad to cover the treated skin. Do not cover treated areas...

Bactroban Generic name: myoo-PEER-oh-sin] Drug class: Medically reviewed by • • • • • • • What is Bactroban? Bactroban is an antibiotic that prevents bacteria from growing on your skin. Bactroban topical (for use on the skin) is used to treat skin infections such as Bactroban may also be used for purposes not listed in this medication guide. Warnings Use Bactroban cream or ointment for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed. Avoid your eyes, nose, mouth, and lips when applying Bactroban. If medication gets in any of these areas, wash with water. Watch for signs of improvement in 3 to 5 days. If your condition gets worse or does not improve, see your doctor. A separate formulation, Bactroban nasal ointment, is available for nasal use. Before taking this medicine You should not use Bactroban cream or ointment if you are allergic to mupirocin. To make sure Bactroban is safe for you, tell your doctor if you have ever had: • kidney disease. Do not use Bactroban on a child without medical advice. The cream should not be used on a child younger than 3 months old. The ointment may be used on a child as young as 2 months old. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether mupirocin topical passes into breast milk or if it could harm a...

This medicine should only be used on the skin. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water. To help clear up your skin infection completely, keep using mupirocin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses. To use: • Wash your hands with soap and water before and after using this medicine. • Apply a thin layer to the affected area of the skin. Rub it in gently. • After applying this medicine, the treated area may be covered with a gauze dressing if desired. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. • For topical dosage form (cream): • For treatment of secondarily infected traumatic skin lesions: • Adults and children 3 months of age and older—Apply three times a day for 10 days. • Children younger than 3 months of age—Use and dose must be determined by your doctor. • For topical ...