Neomycin sulphate polymyxin b sulfate and bacitracin zinc powder

DESCRIPTION: Neomycin and polymyxin B sulfates, bacitracin zinc and hydrocortisone acetate ophthalmic ointment is a sterile antimicrobial and anti-inflammatory ointment for ophthalmic use. Each gram contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, bacitracin zinc equivalent to 400 bacitracin units, hydrocortisone acetate 10 mg (1 %), in a white petrolatum and mineral oil base. Bacitracin zinc is the zinc salt of bacitracin, a mixture of related cyclic polypeptides (mainly bacitracin A) produced by the growth of an organism of the licheniformis group of Bacillus subtilis var Tracy. It has a potency of not less than 40 bacitracin units per mg. The structural formula is: CLINICAL PHARMACOLOGY: Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body's defense mechanism against infection, concomitant antimicrobial drugs may be used when this inhibition is considered to be clinically significant in a particular case. When a decision to administer both a corticosteroid and antimicrobials is made, the administration of such drugs in combination has the advantage of greater patient compliance and convenience, with the added assurance that the appropriate dosage of all drugs is administered. When each type of drug is in the same formulation, compatibility of ingredients is assured and the correct volume of dru...

Bacitracin, neomycin, and polymyxin B (topical) Generic name: bacitracin, neomycin, and polymyxin B (topical) [ BAS-i-TRAY-sin, NEE-oh-MYE-sin, POL-ee-MIX-in-B] Brand names: Tribiotic Plus, NEO TO GO!, Curad Triple Antibiotic Dosage form: topical ointment (400 units-3.5 mg-5000 units/g) Drug class: • • • • • • Related/similar drugs Before taking this medicine You should not use this medication if you are allergic to bacitracin, neomycin, or polymyxin B. Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially: • chronic ear infections; or • a ruptured (torn) eardrum. It is not known whether bacitracin, neomycin, and polymyxin B topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether bacitracin, neomycin, and polymyxin B topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Bacitracin, neomycin, and polymyxin B topical should not be used on a child younger than 2 years old without medical advice. How should I use bacitracin, neomycin, and polymyxin B? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Before you apply this medication, wash the skin area with soap and water and then dry it thoroughly. Do not apply the ointment over large skin areas. Do not use on a ...

Bacitracin Zinc Plus Neomycin Plus Polymyxin B A triple antibiotic ointment or antiseptic skin sealant, an iodine/alcohol disinfectant solution (DuraPrep, 3M US, St. Paul, MN) (see Chapter 10), may be applied at the insertion site on the skin to decrease the risk of infection. From: Equine Surgery (Fourth Edition), 2012 Related terms: • Antiinfective Agent • Antibiotic Agent • Psittacine • Ratite • Passeriformes • Parrot • Columbidae • Ostrich In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (Fifteenth Edition), 2006 General Information The polymyxins are antibacterial agents that are produced from different strains of Bacillus polymyxa. Because of their poor tissue distribution and their substantial nephrotoxicity and neurotoxicity, they are mainly restricted to topical use. However, they can be considered for serious systemic infections caused by multidrug-resistant Gram-negative bacteria (1–4). The polymyxins that are used clinically are polymyxin B (rINN) and colistin (pINN, formerly known as polymyxin E). Colistimethate sodium (rINN, also called colistin methanesulfonate and colistin sulfomethate sodium) is prepared from colistin. The polymyxins are cationic, basic, and amphipathic polypeptides that interact with lipopolysaccharides in the outer membrane of bacilli. They potently neutralize endotoxin, reduce blood endotoxin concentrations in patients with septic shock during direct hemoperfusion over immobili...

Neosporin is a brand of triple-antibiotic ointment. It contains bacitracin zinc, neomycin sulfate, and polymyxin B sulfate. Bacitracin ointment is also available, and it does not include the other two antibiotics. While both types of cream can help treat minor scratches, cuts, and burns, many people are allergic to bacitracin. In this article, learn more about the differences between Neosporin and bacitracin-only ointments and whether they are necessary. Share on Pinterest People with weak immune systems may benefit from antibiotic ointments, as they can reduce the risk of infection. Bacitracin and Neosporin are both topical antibiotics — medicated creams that a person can use directly on their skin. Doctors sometimes call Neosporin “neo-bac-polym” because of the combination of antibiotics that it contains. Some pharmacies also sell triple antibiotic ointments that are generic versions of Neosporin. The formulations in these vary among manufacturers — they may contain slightly different ingredients from Neosporin or different proportions of each ingredient. Bacitracin ointment only contains one antibiotic. This means that Neosporin offers broader antibiotic coverage that may fight more types of bacteria. However, no recent research has directly compared Neosporin to bacitracin-only ointment, so it is unclear whether one is safer or more effective than the other. Doctors have used bacitracin and ointments containing it since Bacitracin and Neosporin ointments have similar u...