Osteoporosis treatment

  1. A new therapy for osteoporosis: Romosozumab
  2. Osteoporosis: Everything You Need to Know
  3. Osteoporosis drugs: Which one is right for you?
  4. What is Osteoporosis?
  5. Osteoporosis Lifestyle Changes to Improve Bone Health
  6. Osteoporosis: Everything You Need to Know
  7. A new therapy for osteoporosis: Romosozumab
  8. Osteoporosis Lifestyle Changes to Improve Bone Health
  9. What is Osteoporosis?
  10. Osteoporosis drugs: Which one is right for you?


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A new therapy for osteoporosis: Romosozumab

Osteoporosis is a condition in which bones become porous (less dense) and weaker. It affects 10 million people in the United States: approximately eight million women and two million Which medications can help treat osteoporosis? There are currently several medications available to treat osteoporosis. These include medications that • block the breakdown of bone (anti-resorptive therapies). Examples include bisphosphonates such as alendronate (Fosamax), which is a pill, and zoledronate (Reclast), which is given intravenously. Other types of anti-resorptive agents include raloxifene (Evista) and denosumab (Prolia). • enhance the formation of bone (anabolic therapies). Examples include teriparatide (Forteo) and abaloparatide (Tymlos). Now, for the first time since 2010, a new class of medication is available to treat osteoporosis. Romosozumab (Evenity) is in a class called sclerostin inhibitors and is considered an anabolic agent. Sclerostin is a protein that helps regulate bone metabolism. Produced by osteocytes (bone cells), it inhibits bone formation (making new bone). Romosozumab binds sclerostin, which keeps it from blocking the signaling pathway for new bone formation. The result is an increase in new bone. To a lesser degree, it also decreases bone resorption (breakdown of bone). Romosozumab is approved by the FDA to treat osteoporosis in women who have completed menopause and are at high risk for fracture. A history of fracture due to osteoporosis, multiple risk facto...

Osteoporosis: Everything You Need to Know

Share on Pinterest What is osteoporosis? Osteoporosis is a condition that affects the bones. Its name comes from Latin for “porous bones.” The inside of a healthy bone has small spaces, like a honeycomb. Osteoporosis increases the size of these spaces, causing the bone to lose strength and density. In addition, the outside of the bone grows weaker and thinner. Osteoporosis can occur in people of any age, but it’s more common in older adults, especially women. More than People with osteoporosis are at a high risk of fractures, or bone breaks, while doing routine activities such as standing or walking. The most commonly affected bones are the ribs, hips, and the bones in the wrists and spine. The early stages of osteoporosis don’t cause any symptoms or warning signs. In most cases, people with osteoporosis don’t know they have the condition until they have a fracture. If • receding gums • weakened grip strength • weak and brittle nails If you don’t have symptoms but have a family history of osteoporosis, talking to your doctor can help you assess your risk. Without appropriate treatment, osteoporosis can worsen. As bones get thinner and weaker, the risk of fracture increases. Symptoms of severe osteoporosis can include a fracture from a fall or even from a strong sneeze or cough. They can also include back or neck pain, or loss of height. Back or neck pain or loss of height can be caused by a If you do have a Age The biggest risk factor of osteoporosis is age. Throughout you...

Osteoporosis drugs: Which one is right for you?

There's no one-size-fits-all answer when it comes to osteoporosis. Understanding your options begins with knowing what's available. Throughout our lives, our bones undergo constant renovation. In a process called bone turnover, cells called osteoclasts break down and remove old bone, and then cells called osteoblasts lay down new bone. After menopause, the rate of bone removal speeds up, and bone formation doesn't always keep pace. The net result can be bone loss and ultimately the weakened, brittle bones of Even if you've been diagnosed with osteoporosis, a fracture isn't inevitable. Many drugs available today can slow the rate of Your doctor will determine whether you have osteoporosis by measuring your bone density—usually at the hip and spine—using dual energy x-ray absorptiometry (DEXA). The result, expressed as a number called a T-score, compares your bone density with that of a healthy 30-year-old woman. The doctor will likely recommend medicine if you have • a T-score of –2.5 or lower—the definition of osteoporosis • a history of hip or vertebral (spinal) fracture caused by a fall while standing (in contrast to a fall from a height) • a T-score between –1.0 and –2.5 (called Osteoporosis treatment: Where to start To slow bone breakdown, many doctors first turn to one particular class of drugs. If someone has a very low T-score, doctors typically start with the bisphosphonates. There are several bisphosphonates to choose from: • pills, such as alendronate (Fosamax), ...

What is Osteoporosis?

What to Know About Osteoporosis Osteoporosis, which means "porous bones," is a condition that causes bones to gradually thin and weaken, leaving them at greater risk of Although all bones can be affected by the disease, the bones of the spine, hip, and wrist are most likely to break. In older people, hip fractures can be particularly dangerous. Having to stay still for a long time during the healing process can lead to possibly deadly complications, like Of the estimated 10 million Americans who have What Causes Osteoporosis? When people are young, bone in their bodies is broken down and replaced continuously, a process known as bone remodeling. Bone mass usually peaks in a person's mid to late 20s. For women, the loss of bone density speeds up during the first 5 to 7 years after Although some loss of bone density is a natural part of aging, you’re at higher risk for getting the very porous bones and fractures associated with • Are thin or have a small frame • Smoke, drink more than moderately, or live a sedentary lifestyle • Have a family history of hip fracture • Had your ovaries removed, especially before age 40 • Are white or Asian Certain medical conditions that increase bone breakdown, including Bone Health and Your Lifestyle Habits Your everyday habits -- good and bad -- affect bone health. How do your habits stack up? • Vitamin D and calcium. Not getting enough vitamin D or calcium can weaken your bones. The National Institutes of Health recommends adults up to 70 ...

Osteoporosis Lifestyle Changes to Improve Bone Health

• Older age • Female sex assigned at birth • Thin-boned, slender body frame • Family history of osteoporosis • Low levels of estrogen or testosterone • Consuming a diet low in calcium and vitamin D • Using certain medications, such as glucocorticoids, proton pump inhibitors, and more • Family history of osteoporosis • Certain medical conditions like rheumatoid arthritis, gastrointestinal diseases, and more • Smoking, heavy alcohol drinking, and low physical activity levels Federal guidelines recommend that women over the age of 50 and men over the age of 70 get a daily calcium intake of 1,200 milligrams (mg) and a daily vitamin D intake of 800 international units (IU). A vitamin supplement may be recommended by your healthcare provider if you're not able to make dietary modifications. An exercise routine is a key part of an osteoporosis treatment plan. Just be sure to discuss with your healthcare provider which exercises will be safest for you based on your specific osteoporosis case. Limit Alcohol, Smoking, and Caffeine As with food, people with osteoporosis should also be mindful of the other substances they consume—like alcohol, tobacco, and caffeine. Remember that incorporating these lifestyle changes is meant to supplement osteoporosis medication and become a part of your treatment plan—not replace any prescriptions or therapies that your healthcare provider has recommended. Prevent Falls and Fractures It's important to reduce the risk of breaking or fracturing a bone...

Osteoporosis: Everything You Need to Know

Share on Pinterest What is osteoporosis? Osteoporosis is a condition that affects the bones. Its name comes from Latin for “porous bones.” The inside of a healthy bone has small spaces, like a honeycomb. Osteoporosis increases the size of these spaces, causing the bone to lose strength and density. In addition, the outside of the bone grows weaker and thinner. Osteoporosis can occur in people of any age, but it’s more common in older adults, especially women. More than People with osteoporosis are at a high risk of fractures, or bone breaks, while doing routine activities such as standing or walking. The most commonly affected bones are the ribs, hips, and the bones in the wrists and spine. The early stages of osteoporosis don’t cause any symptoms or warning signs. In most cases, people with osteoporosis don’t know they have the condition until they have a fracture. If • receding gums • weakened grip strength • weak and brittle nails If you don’t have symptoms but have a family history of osteoporosis, talking to your doctor can help you assess your risk. Without appropriate treatment, osteoporosis can worsen. As bones get thinner and weaker, the risk of fracture increases. Symptoms of severe osteoporosis can include a fracture from a fall or even from a strong sneeze or cough. They can also include back or neck pain, or loss of height. Back or neck pain or loss of height can be caused by a If you do have a Age The biggest risk factor of osteoporosis is age. Throughout you...

A new therapy for osteoporosis: Romosozumab

Osteoporosis is a condition in which bones become porous (less dense) and weaker. It affects 10 million people in the United States: approximately eight million women and two million Which medications can help treat osteoporosis? There are currently several medications available to treat osteoporosis. These include medications that • block the breakdown of bone (anti-resorptive therapies). Examples include bisphosphonates such as alendronate (Fosamax), which is a pill, and zoledronate (Reclast), which is given intravenously. Other types of anti-resorptive agents include raloxifene (Evista) and denosumab (Prolia). • enhance the formation of bone (anabolic therapies). Examples include teriparatide (Forteo) and abaloparatide (Tymlos). Now, for the first time since 2010, a new class of medication is available to treat osteoporosis. Romosozumab (Evenity) is in a class called sclerostin inhibitors and is considered an anabolic agent. Sclerostin is a protein that helps regulate bone metabolism. Produced by osteocytes (bone cells), it inhibits bone formation (making new bone). Romosozumab binds sclerostin, which keeps it from blocking the signaling pathway for new bone formation. The result is an increase in new bone. To a lesser degree, it also decreases bone resorption (breakdown of bone). Romosozumab is approved by the FDA to treat osteoporosis in women who have completed menopause and are at high risk for fracture. A history of fracture due to osteoporosis, multiple risk facto...

Osteoporosis Lifestyle Changes to Improve Bone Health

• Older age • Female sex assigned at birth • Thin-boned, slender body frame • Family history of osteoporosis • Low levels of estrogen or testosterone • Consuming a diet low in calcium and vitamin D • Using certain medications, such as glucocorticoids, proton pump inhibitors, and more • Family history of osteoporosis • Certain medical conditions like rheumatoid arthritis, gastrointestinal diseases, and more • Smoking, heavy alcohol drinking, and low physical activity levels Federal guidelines recommend that women over the age of 50 and men over the age of 70 get a daily calcium intake of 1,200 milligrams (mg) and a daily vitamin D intake of 800 international units (IU). A vitamin supplement may be recommended by your healthcare provider if you're not able to make dietary modifications. An exercise routine is a key part of an osteoporosis treatment plan. Just be sure to discuss with your healthcare provider which exercises will be safest for you based on your specific osteoporosis case. Limit Alcohol, Smoking, and Caffeine As with food, people with osteoporosis should also be mindful of the other substances they consume—like alcohol, tobacco, and caffeine. Remember that incorporating these lifestyle changes is meant to supplement osteoporosis medication and become a part of your treatment plan—not replace any prescriptions or therapies that your healthcare provider has recommended. Prevent Falls and Fractures It's important to reduce the risk of breaking or fracturing a bone...

What is Osteoporosis?

What to Know About Osteoporosis Osteoporosis, which means "porous bones," is a condition that causes bones to gradually thin and weaken, leaving them at greater risk of Although all bones can be affected by the disease, the bones of the spine, hip, and wrist are most likely to break. In older people, hip fractures can be particularly dangerous. Having to stay still for a long time during the healing process can lead to possibly deadly complications, like Of the estimated 10 million Americans who have What Causes Osteoporosis? When people are young, bone in their bodies is broken down and replaced continuously, a process known as bone remodeling. Bone mass usually peaks in a person's mid to late 20s. For women, the loss of bone density speeds up during the first 5 to 7 years after Although some loss of bone density is a natural part of aging, you’re at higher risk for getting the very porous bones and fractures associated with • Are thin or have a small frame • Smoke, drink more than moderately, or live a sedentary lifestyle • Have a family history of hip fracture • Had your ovaries removed, especially before age 40 • Are white or Asian Certain medical conditions that increase bone breakdown, including Bone Health and Your Lifestyle Habits Your everyday habits -- good and bad -- affect bone health. How do your habits stack up? • Vitamin D and calcium. Not getting enough vitamin D or calcium can weaken your bones. The National Institutes of Health recommends adults up to 70 ...

Osteoporosis drugs: Which one is right for you?

There's no one-size-fits-all answer when it comes to osteoporosis. Understanding your options begins with knowing what's available. Throughout our lives, our bones undergo constant renovation. In a process called bone turnover, cells called osteoclasts break down and remove old bone, and then cells called osteoblasts lay down new bone. After menopause, the rate of bone removal speeds up, and bone formation doesn't always keep pace. The net result can be bone loss and ultimately the weakened, brittle bones of Even if you've been diagnosed with osteoporosis, a fracture isn't inevitable. Many drugs available today can slow the rate of Your doctor will determine whether you have osteoporosis by measuring your bone density—usually at the hip and spine—using dual energy x-ray absorptiometry (DEXA). The result, expressed as a number called a T-score, compares your bone density with that of a healthy 30-year-old woman. The doctor will likely recommend medicine if you have • a T-score of –2.5 or lower—the definition of osteoporosis • a history of hip or vertebral (spinal) fracture caused by a fall while standing (in contrast to a fall from a height) • a T-score between –1.0 and –2.5 (called Osteoporosis treatment: Where to start To slow bone breakdown, many doctors first turn to one particular class of drugs. If someone has a very low T-score, doctors typically start with the bisphosphonates. There are several bisphosphonates to choose from: • pills, such as alendronate (Fosamax), ...