In humans, the skeletal system consists of bones, joints and associated cartilages. An adult human has 206 bones in their body and variety of different joints. Skeletal System Diagram. Image shows a human skeleton with the major bones labeled.

Skeletal fluorosis is a long-term bone disease that develops when prolonged fluoride toxicity leads to osteosclerosis and bone deformities that result in crippling pain and debility. The disease is endemic to many countries due to environmental or industrial exposures.