Thyroid normal range

Clinical Information Thyroglobulin (Tg) is a thyroid-specific glycoprotein (approximately 660 kDa) that serves as the source for thyroxine (T4) and triiodothyronine (T3) production within the lumen of thyroid follicles. For T4 and T3 release, Tg is reabsorbed into thyrocytes and proteolytically degraded, liberating T4 and T3 for secretion. Small amounts of intact Tg are secreted alongside T4 and T3 and are detectable in the serum of healthy individuals, with levels roughly paralleling thyroid size (0.5-1.0 ng/mL Tg per gram thyroid tissue, depending on thyroid-stimulating hormone: TSH level). In situations of disordered thyroid growth (eg, goiter), increased thyroid activity (eg, Graves disease), or glandular destruction (eg, thyroiditis) larger amounts of Tg may be released into the circulation. Clinically, the main use of serum Tg measurements is in the follow-up of differentiated follicular cell-derived thyroid carcinoma. Because Tg is thyroid-specific, serum Tg concentrations should be undetectable, or very low, after the thyroid gland is removed during treatment for thyroid cancer. Current clinical guidelines consider a serum Tg of more than 1 ng/mL in an athyrotic individual as suspicious of possible residual or recurrent disease. To improve diagnostic accuracy, it is recommended this measurement be initially obtained after TSH stimulation, either following thyroid hormone withdrawal or after injection of recombinant human TSH. Most patients will have a relatively lo...

A TSH test measures the amount of TSH in your blood. By measuring TSH levels, you can find out if your thyroid is making the right level of thyroid hormones. If your TSH levels are too high or too low, that might mean that the hormone is stimulating your thyroid too much or not enough, potentially pointing to a condition that needs addressing. The pituitary and thyroid glands work together to maintain the level of thyroid hormones in your blood. As the pituitary releases more TSH, more thyroid hormones get released. TSH levels may increase or decrease in different health conditions. In some cases, the TSH levels rise before the symptoms of the disease even appear. What Is a TSH Test? A TSH test measures the level of TSH in your blood. Knowing how much TSH is in your blood can reveal whether your thyroid is working properly. A healthcare provider will perform a TSH test by drawing blood from a vein in your arm. That blood sample is then sent to a laboratory, where levels of TSH in the blood are measured. • Graves’ disease: This autoimmune disorder that attacks the thyroid is the most common cause. • Toxic multinodular goiter: This condition, which involves an enlarged thyroid gland, is the most common cause among older people. • Inflammation of the thyroid (thyroiditis): This can be due to medication or a viral infection and can also happen after pregnancy. Treatment for Abnormal TSH Levels If you have abnormal levels of TSH, your healthcare provider will likely order more ...