Alp normal range

You should not eat or drink anything for 6 hours before the test, unless your health care provider tells you otherwise. Many medicines can interfere with blood test results. • Your provider will tell you if you need to stop taking any medicines before you have this test. • DO NOT stop or change your medicines without talking to your provider first. The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women. The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. Abnormal results may be due to the following conditions: Higher-than-normal ALP levels • • Bone disease • Eating a fatty meal if you have blood type O or B • Healing fracture • • • Hyperthyroidism • Leukemia • Liver disease • Lymphoma • Osteoblastic bone tumors • Osteomalacia • • Sarcoidosis Lower-than-normal ALP levels • Hypophosphatasia • Hypothyroidism • Malnutrition • Pernicious anemia • • Wilson disease • Zinc deficiency Other conditions for which the test may be done: • • • • Gallstones • • • Pancreatitis • Fogel EL, Sherman S. Diseases of the gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 202...

Clinical Information Alkaline phosphatase (ALP) is present in a number of tissues including liver, bone, intestine, and placenta. The activity of ALP found in serum is a composite of isoenzymes from those sites and, in some circumstances, placental or Regan isoenzymes. Serum ALP is of interest in the diagnosis of 2 main groups of conditions: hepatobiliary disease and bone disease associated with increased osteoblastic activity. A rise in ALP activity occurs with all forms of cholestasis, particularly with obstructive jaundice. The response of the liver to any form of biliary tree obstruction is to synthesize more ALP. The main site of new enzyme synthesis is the hepatocytes adjacent to the biliary canaliculi. ALP is also elevated in disorders of the skeletal system that involve osteoblast hyperactivity and bone remodeling, such as Paget disease, rickets, osteomalacia, fractures, and malignant tumors. Moderate elevation of ALP may be seen in other disorders such as Hodgkin disease, congestive heart failure, ulcerative colitis, regional enteritis, and intra-abdominal bacterial infections. Interpretation Total Alkaline Phosphatase: Alkaline phosphatase (ALP) elevations tend to be more marked (more than 3-fold) in extrahepatic biliary obstructions (eg, by stone or cancer of the head of the pancreas) than in intrahepatic obstructions: the more complete the obstruction, the greater the elevation. With obstruction, serum ALP activities may reach 10 to 12 times the upper limit of ...

Overview What are liver function tests? Liver function tests are What are the five primary liver function tests? The most common liver tests include: • Liver enzymes test. Your • Total protein test. A total protein test measures levels of protein in your blood. Your liver makes protein, and low protein levels may indicate that your liver isn’t functioning optimally. • Bilirubin test. Bilirubin is a waste product that your liver deposits in bile. • LDH test. Lactate dehydrogenase (LDH) is an enzyme found in many of your body’s tissues, including your liver. • Prothrombin Time (PT) test. This test measures how long it takes for a sample of your blood to clot, a process that involves proteins that your liver produces. These tests are all part of a routine blood panel called a When are tests done to check liver function? Your healthcare provider might want to check these values to screen you for possible hepatitis or other liver diseases. If they already know that you have What kinds of things can a liver panel tell you? Different values and ratios of different substances may tell your healthcare provider: • If you have liver inflammation (hepatitis). • Whether the inflammation is • Whether you have a problem in your liver itself or in your bile ducts. • If your liver function is impaired, and if so, how much. • If your bile flow is impaired, and if so, how much. • Whether your medications are affecting your liver, and if so, how much. Test Details How do liver function tests ...

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A number of pitfalls can be encountered in the interpretation of common blood liver function tests. These tests can be normal in patients with chronic hepatitis or cirrhosis. The normal range for aminotransferase levels is slightly higher in males, nonwhites and obese persons. Severe alcoholic hepatitis is sometimes confused with cholecystitis or cholangitis. Conversely, patients who present soon after passing common bile duct stones can be misdiagnosed with acute hepatitis because aminotransferase levels often rise immediately, but alkaline phosphatase and γ-glutamyltransferase levels do not become elevated for several days. Asymptomatic patients with isolated, mild elevation of either the unconjugated bilirubin or the γ-glutamyltransferase value usually do not have liver disease and generally do not require extensive evaluation. Overall hepatic function can be assessed by applying the values for albumin, bilirubin and prothrombin time in the modified Child-Turcotte grading system. Abnormal LFTs often, but not always, indicate that something is wrong with the liver, and they can provide clues to the nature of the problem. However, normal LFTs do not always mean that the liver is normal. Patients with cirrhosis and bleeding esophageal varices can have normal LFTs. Of the routine LFTs, only serum albumin, bilirubin and prothrombin time (PT) provide useful information on how well the liver is functioning. Situation Comments Mildly elevated ALT level (less than 1.5 times norm...

An alkaline phosphatase level test (ALP test) measures the amount of alkaline phosphatase enzyme in your bloodstream. The test requires a simple blood draw and is often a routine part of other blood tests. Abnormal levels of ALP in your blood most often indicate a health concern with your The normal range of ALP varies from person to person and depends on your age, A 2013 research review showed that the normal range for a serum ALP level in healthy adults is The normal range runs higher in children and decreases with age. The best way to know what is normal or not is to discuss the results with your doctor, who will be able to interpret the lab’s specific result and reference ranges. What is alkaline phosphatase? ALP is an enzyme Your liver is one of the main sources of ALP, but some is also made in your bones, An ALP test may be performed to determine how well your liver and gallbladder are functioning or to identify concerns with your bones. Liver and gallbladder Checking ALP levels in the blood is a routine part of liver function and gallbladder tests. Symptoms such as The ALP test can be helpful in identifying conditions such as: • blockage of • • • some forms of You may also need an ALP test if you’re taking a medication that has the potential to damage your liver, such as acetaminophen (Tylenol). Measuring ALP is one way to check for that damage and is typically done together with other Bones The ALP test can be helpful in the diagnosis of bone concerns • • • ALP tes...

Overview Liver function tests are blood tests used to help diagnose and monitor liver disease or damage. The tests measure the levels of certain enzymes and proteins in your blood. Some of these tests measure how well the liver is performing its normal functions of producing protein and clearing bilirubin, a blood waste product. Other liver function tests measure enzymes that liver cells release in response to damage or disease. Why it's done Liver function tests can be used to: • Screen for liver infections, such as hepatitis • Monitor the progression of a disease, such as viral or alcoholic hepatitis, and determine how well a treatment is working • Measure the severity of a disease, particularly scarring of the liver (cirrhosis) • Monitor possible side effects of medications Liver function tests check the levels of certain enzymes and proteins in your blood. Levels that are higher or lower than normal can indicate liver problems. Some common liver function tests include: • Alanine transaminase (ALT). ALT is an enzyme found in the liver that helps convert proteins into energy for the liver cells. When the liver is damaged, ALT is released into the bloodstream and levels increase. • Aspartate transaminase (AST). AST is an enzyme that helps metabolize amino acids. Like ALT, AST is normally present in blood at low levels. An increase in AST levels may indicate liver damage, disease or muscle damage. • Alkaline phosphatase (ALP). ALP is an enzyme found in the liver and bone a...