Milk of magnesia formula

Dosage Forms & Strengths chewable tablet • 311mg • 400mg suspension • 7.75% • 400mg/5mL • 800mg/5mL • 1200mg/15mL • 2400mg/10mL Constipation Magnesium hydroxide (400 mg/5 mL): 30-60 mL/day PO at bedtime or in divided doses Magnesium hydroxide (800 mg/5 mL): 15-30 mL/day PO at bedtime or in divided doses Chewable tablet: 8 tablets/day PO at bedtime or in divided doses Acid Indigestion Magnesium hydroxide (400 mg/5 mL): 5-15 mL PO q4hr; no more than 4 doses per 24-hour period Chewable tablet: 2-4 tablets PO q4hr; no more than 4 doses per 24-hour period Dosage Forms & Strengths chewable tablet • 311mg • 400mg suspension • 7.75% • 400mg/5mL • 800mg/5mL • 1200mg/15mL • 2400mg/10mL Constipation 12 years: 8 tablets PO once daily or in divided doses Acid Indigestion Liquid • <12 years: Not recommended • ≥12 years: 5-15 mL (400 mg/5 mL) PO q4hr; no more than 4 doses per 24-hour period Chewable tablet • <12 years: Not recommended • ≥12 years: 2-4 tablets PO q4hr; no more than 4 doses per 24-hour period Contraindicated (0) Serious - Use Alternative (13) • baloxavir marboxil magnesium hydroxide will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Avoid or Use Alternate Drug. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Human studies not conducted. • demeclocycline magnesium hydroxide decreases levels of ...

Magnesium hydroxide - Mg(OH) 2 What is Magnesium hydroxide? Magnesium Hydroxide is an inorganic compound which has a low solubility in water. It is also called Milk of magnesia or magnesium(2+) hydroxide. Naturally, it occurs in the form of a mineral brucite and is a common compound found in antacids. The Mg(OH) 2. Table of Contents • • • • • • • History of Magnesium hydroxide In the year 1872, Charles Henry Phillips was the first to use the term milk of magnesia. It was used for the suspension of magnesium hydroxide Mg(OH) 2 formulated at about 8%w/v. Properties of Magnesium hydroxide – Mg(OH) 2 Magnesium hydroxide Mg(OH) 2 Molecular Weight of Magnesium hydroxide 58.3197 g/mol Density of Magnesium hydroxide 2.3446 g/cm 3 Melting Point of Magnesium hydroxide 350 °C Monoisotopic Mass 57.991 g/mol Structure of Magnesium hydroxide (Mg(OH) 2) Structure of Magnesium hydroxide Uses of Magnesium hydroxide (Mg(OH) 2) • Magnesium hydroxide is an excellent thermal conductor and poor electrical conductor. • It is used in suspensions as a laxative or • Used as a food additive. • It is widely used in waste-water treatment. • Used as a fire retardant. • It is used in wet plate collodion process as a photographic fixer. • It is used in gold mining. • Used in warehouses. Preparation of Magnesium hydroxide When a solution of magnesium salts is combined with alkaline water it instigates precipitation of solid magnesium hydroxide. The reaction is as follows: Mg 2+ + 2 OH − → Mg(OH) 2 Co...

\( \newcommand\) No headers Required Training Required PPE UC Lab Safety Fundamentals Lab coat, safety glasses/goggles , nitrile gloves Equipment Chemicals 400 mL Beaker 100 mL Milk of Magnesia Stir Rod 100 mL 6N HCl 100 mL 6N NaOH Procedure: • Pour 100 mL of Milk of Magnesia into the beaker • Add 6N HCl with stirring until suspension dissolves • Add 6N NaOH until suspension returns • Can be repeated multiple times Discussion: Milk of Magnesia is a milky white suspension of magnesium hydroxide, Mg(OH) 2, used as an antacid and laxative. Mg(OH) 2 is sparingly soluble in water. Mg(OH) 2⇌ Mg 2+ + 2 OH - K sp = 1.5x10 -11 Adding 6N HCl to the solution removes some of the OH - ions in the solution shifting the equilibrium to the right allowing more Mg(OH) 2 to dissolve. Adding 6N NaOH adds OH - and shifts the equilibrium to the left and causing Mg(OH) 2 to precipitate back out of solution. Hazards: 6N HCl and 6N NaOH can cause serious burns if contact is made with skin or eyes. If contact occurs, rinse the affected area with water for at least 15 minutes. SOP: Corrosive – Hydrochloric Acid, Sodium Hydroxide Disposal (by Storeroom) The solutions should be neutralized and flushed down the drain with copious water.

Description and Brand Names Drug information provided by: US Brand Name • Almora • Citrate Of Magnesia • Dewees Carminative • Elite Magnesium • Mag-Gel 600 • Maginex • Mag-Tab SR • Phillips Milk of Magnesia Canadian Brand Name • Citracal Slow Release • Mag 2 • Mag Citrate • Magnesium-Rougier • Royvac Magnesium Citrate Descriptions Magnesium is used as a dietary supplement for individuals who are deficient in magnesium. Although a balanced diet usually supplies all the magnesium a person needs, magnesium supplements may be needed by patients who have lost magnesium because of illness or treatment with certain medicines. Lack of magnesium may lead to irritability, muscle weakness, and irregular heartbeat. Injectable magnesium is given only by or under the supervision of a health care professional. Some oral magnesium preparations are available only with a prescription. Others are available without a prescription. Importance of Diet For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement. The best dietary sources of magnesium include green leafy vegetables, nuts, peas, beans, and cereal grains in which the germ or outer layers have no...

Brief Description: A solution of milk of magnesia and universal indicator in water is stirred while acetic acid is added. The indicator changes color as the acid is neutralized. As the suspended solid is consumed, the solution becomes clear. Purpose/Goal: Procedure demonstrates the neutralizing effect of magnesium hydroxide on an acid, color change of indicators with pH, and vividly illustrates how a commercial antacid works. Explanation of Experiment: Magnesium hydroxide reacts with acid to form water and magnesium ions: Mg(OH) 2 (s) + 2 H 3O + (aq) = 4 H 2O (l) + Mg 2+ (aq) Indicators are substances which have distinctly different colors in acidic or basic media. An insoluble base in water dissolves in the presence of acid. Milk of Magnesia has a neutralizing effect on stomach acid – this experiment shows its effects. Materials Preparation: • Milk of Magnesia – any brand should work - primary ingredient should be magnesium hydroxide - Mg(0H)2. • Universal Indicator - available from any chemical supplier. • Vinegar (ca. 5% acetic acid)- available from any grocery store. • Magnetic stirring bar and stirring plate, preferably lighted from below. • Beaker – 500 or 1000 mL Presentation: Place about 100 mL of Milk of Magnesia in a 500 mL beaker and dilute with tap water until the beaker is about half full. Add about 10 mL of Universal Indicator. The Universal Indicator will turn red on the far acidic end of the scale and dark blue on the alkaline side. Use the lighted magnetic...

Summary In this demonstration, students will observe a color change in a milk of magnesia solution as vinegar is added. Grade Level High school AP Chemistry Curriculum Framework This demonstration supports the following unit, topics and learning objectives: • Unit 4: Chemical Reactions • Topic 4.3: Representations of Reactions • TRA-1.C: Represent a given chemical reaction or physical process with a consistent particulate model. • Topic 4.5: Stoichiometry • SPQ-4.A: Explain changes in the amounts of reactants and products based on the balanced reaction equation for a chemical process. • Topic 4.7: Types of Reactions • TRA-2.A: Identify a reaction as acid-base, oxidation-reduction, or precipitation. • Unit 5: Kinetics • Topic 5.1: Reaction Rates • TRA-3.A: Explain the relationship between the rate of a chemical reaction and experimental parameters. • Unit 8: Acids and Bases • Topic 8.3: Weak Acid and Base Equilibria • SAP-9.C: Explain the relationship among pH, pOH, and concentrations of all species in a solution of a monoprotic weak acid or weak base. • Topic 8.7: pH and pKa • SAP-10.A: Explain the relationship between the predominant form of a weak acid or base in solution at a given pH and the pKa of the conjugate acid or the pKb of the conjugate base. Objectives By the end of this demonstration, students should be able to • Understand that a chemical change is taking place. • Recognize that an indicator causes the color change. • Realize that an acid base reaction is ta...