Principle of dialysis

• Two tubes are connected via your • If your doctor prescribes blood thinner as part of your treatment, it will be added to keep your blood from clotting while it’s in the machine. • A pressure monitor and pump work together to keep the flow at the right rate. • Your blood enters the dialyzer, where it is filtered. • Dialysate solution enters the dialyzer. It draws the waste out of your blood. • Used dialysate solution is pumped out of the machine and discarded. • Your blood goes through another pressure monitor and an air trap to make sure it’s safe to go back into your body. • Your cleaned blood returns to your body through the second tube attached to your access site. What is dialysate? Dialysate is a fluid that is made up of water, electrolytes and salts. During dialysis, dialysate helps to clean your blood inside the dialyzer by removing waste products and balancing electrolytes. Your nephrologist will prescribe the dialysate that is right for your body’s needs. • The core of the dialyzer is made up of thousands of tiny mesh tubes. • Your blood flows inside each tube, and the dialysate stays on the outside of the tubes. • Tiny pores in the tubes let waste and excess fluids pass from your blood into the dialysate. • Your cleaned blood then leaves the dialyzer and is returned to your body. How is my dialysis treatment monitored? During your dialysis session, detailed information will show on the machine’s monitoring screen. Every function will be monitored, including th...

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Please Dialysis Core Curriculum (2021) Co-Chairs: Nwamaka D. Eneanya, MD, MPH, FASN; B. Peter Emile Sawaya, MD, FASN Deputy Chair: Javier A. Neyra, MD, MS, FASN Over 850 million people worldwide are affected by kidney diseases. Recognizing the importance and centrality of dialysis therapy to training and patient care, ASN has updated the Dialysis Core Curriculum to close the knowledge and/or performance-in-practice gaps of nephrology professionals regarding quality, patient-centered healthcare. This curriculum consists of PowerPoint slides that cover the breadth of dialysis, including basic principles to treatment options to complications to administration considerations, and more. New features include: downloadable presentations with notes and a zoom feature. Please note, audio is not included as part of the PowerPoint file. Questions? Please contact

Table of Contents • • • • • • • • • • • • • • • • • • • • • • • • • • • • • What is the role of diffusion in dialysis? Summary of diffusion with hemodialysis The formal definition of diffusion in dialysis is movement of solutes as a result of random molecular motions across a semipermeable membrane down its concentration gradient. With dialysis most of the toxin removal is accomplished by diffusion. What should KT V be? In continuous ambulatory peritoneal dialysis (CAPD), the guidelines recommend a weekly Kt/V of at least 2.0, taking into account any remaining kidney function along with the CAPD treatment. In PD, Kt/V is measured by collecting drained dialysate along with any urine you produce in a 24-hour period. What is TMP in dialysis? The major driving force that determines the rate of ultrafiltration or convective flow is the difference in hydrostatic pressure between the blood compartment and the dialysate compartments across the dialysis membrane; this is called the transmembrane pressure (TMP). Read More: What is competitive non competitive and uncompetitive inhibition? What chemicals are used in dialysis? Dialysate, also called dialysis fluid, dialysis solution or bath, is a solution of pure water, electrolytes and salts, such as bicarbonate and sodium. The purpose of dialysate is to pull toxins from the blood into the dialysate. What is recommended frequency of dialysis? Usually, each hemodialysis treatment lasts about four hours and is done three times per week....