Promethazine hydrochloride

Usual Adult Dose for: • • • • • • • • • Usual Pediatric Dose for: • • • • • Additional dosage information: • • • • • • Usual Adult Dose for Allergic Reaction Oral or Rectal: 6.25 to 12.5 mg orally or rectally before meals and at bedtime, if necessary, OR 25 mg orally or rectally once a day at bedtime Parenteral: 25 mg IM or IV once, and may be repeated within 2 hours if necessary Comments: • Once treatment begins, the dose should be reduced to the smallest effective amount needed to control symptoms. • Minor transfusion and/or amelioration of allergic reactions may be controlled with 25 mg doses. Uses: • Allergic conjunctivitis due to inhalant allergens and foods • Amelioration of allergic reactions to blood or plasma • Dermographism • In anaphylaxis as an adjunct to epinephrine and other standard measures after the acute symptoms have been controlled • Mild, uncomplicated allergic skin manifestations of urticaria and angioedema • Other uncomplicated allergic condition of the immediate type when oral therapy is impossible or contraindicated • Perennial and seasonal allergic rhinitis • Vasomotor rhinitis Usual Adult Dose for Allergic Rhinitis Oral or Rectal: 6.25 to 12.5 mg orally or rectally before meals and at bedtime, if necessary, OR 25 mg orally or rectally once a day at bedtime Parenteral: 25 mg IM or IV once, and may be repeated within 2 hours if necessary Comments: • Once treatment begins, the dose should be reduced to the smallest effective amount needed to control...

Promethazine Generic name: promethazine (oral) [ pro-METH-a-zeen] Brand name: Drug classes: Medically reviewed by • • • • • • • What is promethazine? Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. Promethazine also acts as an Promethazine is used to treat Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections. Warnings Stop using promethazine and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects. Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in a child in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age. Promethazine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which can increase some of the side effects of promethazine. There are many other medicines that can interact with promethazine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep...

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Read the Patient Information Leaflet if available from your Take this If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. The dosage is based on your age, medical condition, and response to treatment. In children, the dosage may also be based on Tell your doctor if your condition does not improve or if it worsens. Drowsiness, To relieve Remember that this Tell your doctor right away if you have any serious side effects, including: Get medical help right away if you have any very serious side effects, including: slow/shallow breathing, This medication may rarely cause a very serious condition called A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. See also Warning section. Before taking Before using this This drug may make you dizzy or drowsy or blur your Before having surgery, tell your doctor or This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use This medication may make you sweat less, making you more ...

Description and Brand Names Drug information provided by: US Brand Name • Phenergan • Promacot Descriptions Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult . Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures . Promethazine may also be used for other conditions as determined by your doctor . This medicine is only available with your doctor's prescription . This product is available in the following dosage forms: • Syrup • Tablet • Portions of this document last updated: June 01, 2023 Copyright: © Merative US L.P. 1973, 2023. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. • •

Promethazine is an antihistamine. You may need to take one or more doses during a day, depending upon the reason you are taking it. Make sure you carefully follow the directions on the label. Promethazine may affect your ability to drive and to use tools or machines. The most common side-effects are feeling sleepy, headache, dry mouth and blurred vision. Type of medicine An antihistamine Used for Allergic conditions such as hay fever; to prevent sickness (nausea); and as a sedative Also called Avomine®, Vertigon® (promethazine teoclate); Phenergan®, Sominex® (promethazine hydrochloride) Available as Tablets, oral liquid medicine and injection Promethazine belongs to a group of medicines known as sedating It is used to prevent (or treat) feelings of sickness (nausea). It is commonly recommended for It is also used to relieve allergies such as Promethazine also makes you feel sleepy (has a sedative effect). It may be taken (for a few days only) to help promote sleep in adults with Promethazine is available on prescription, or you can buy it without a prescription at pharmacies. It is not suitable for children under 2 years of age. Before taking promethazine To make sure this is the right treatment for you, before you start taking promethazine it is important that you discuss the treatment with a doctor or pharmacist if: • You are pregnant, trying for a baby or breastfeeding. • You have a problem with the way your liver works, or if you have a problem with your kidneys. • You...

Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. • For oral dosage form (tablets): • For allergy symptoms: • Adults and teenagers—12.5 milligrams (mg) before meals and at bedtime; or 25 mg at bedtime as needed. • Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. • Children younger than 2 years of age—Use and dose must be determined by your doctor . • For prevention of motion sickness: • Adults and teenagers—25 mg twice daily; this initial dose should be taken one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. On other days of travel, 25 mg may be taken on arising and again before the evening meal. • Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg one-half to one hour before tra...

Promethazine is an antihistamine medicine that relieves the symptoms of allergies. It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines. Promethazine is used for: • short-term sleep problems ( • allergies, including • feeling and being sick (vomiting) – due to • You can buy promethazine from pharmacies, where it's often sold as Avomine, Phenergan or Sominex. Promethazine is also available on prescription. It comes as tablets, capsules and a liquid that you swallow. You can also buy promethazine mixed with other medicines, such as • Do not drink alcohol while taking promethazine. Alcohol increases the risks of side effects. • To help you sleep, take promethazine 20 minutes before you go to bed. It normally takes about 30 minutes to work. • To prevent motion sickness, take promethazine the night before a long journey or 1 to 2 hours before a short journey. • Common side effects of promethazine include drowsiness, headaches, nightmares and feeling dizzy, restless or confused. • When promethazine is mixed with other medicines, it's also known by the brand names Fedril and Night Nurse. 3. Who can and cannot take promethazine Promethazine can be taken by most adults. Children under 6 should not be given cough and cold medicines containing promethazine if they have been bought at a pharmacy. These medicines should only be given if prescribed by a doctor. Some types of promethazine medicines are not suitable for chi...

• Promethazine oral tablet is available as a generic drug only. It doesn’t have a brand-name version. • Promethazine comes in four forms: oral tablet, oral solution, injectable solution, and rectal suppository. • Promethazine oral tablet is used to treat several conditions, such as allergies, motion sickness, nausea and vomiting, FDA warning: Breathing problems in young children • This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous. • Promethazine can cause breathing problems in young children. It should not be used in children younger than 2 years. In children this age, this drug may cause slowed breathing that may result in death. Caution should be used when giving this drug to children older than 2 years. Also, this drug should not be used in children who are taking other drugs that may cause slowed breathing. Other warnings • Extreme drowsiness warning: This drug may cause extreme drowsiness. Don’t drive a car or use machinery until you know how this drug affects you. • Neuroleptic malignant syndrome warning: The use of this drug is linked with neuroleptic malignant syndrome. This condition can be fatal. Symptoms can include • Dementia warning: Promethazine is a prescription drug. It comes as an oral tablet, an oral solution, an injectable solution, and a rectal suppository. Promethazine oral tablet is only available as a...