Sodium bicarbonate injection dose

DOSAGE AND ADMINISTRATION Sodium Bicarbonate Injection, USP is administered by the intravenous route. In cardiac arrest, a rapid intravenous dose of one to two 50 mL vials (44.6 to 100 mEq) may be given initially and continued at a rate of 50 mL (44.6 to 50 mEq) every 5 to 10 minutes if necessary (as indicated by arterial pH and blood gas monitoring) to reverse the acidosis. Caution should be observed in emergencies where very rapid infusion of large quantities of bicarbonate is indicated. Bicarbonate solutions are hypertonic and may produce an undesirable rise in plasma sodium concentration in the process of correcting the metabolic acidosis. In cardiac arrest, however, the risks from acidosis exceed those of hypernatremia. In less urgent forms of metabolic acidosis, Sodium Bicarbonate Injection, USP may be added to other intravenous fluids. The amount of bicarbonate to be given to older children and adults over a four-to-eight-hour period is approximately 2 to 5 mEq/kg of body weight – depending upon the severity of the acidosis as judged by the lowering of total CO 2 content, blood pH and clinical condition of the patient. In metabolic acidosis associated with shock, therapy should be monitored by measuring blood gases, plasma osmolarity, arterial blood lactate, hemodynamics and cardiac rhythm. Bicarbonate therapy should always be planned in a stepwise fashion since the degree of response from a given dose is not precisely predictable. Initially an infusion of 2 to 5 mE...

What Is Sodium Bicarbonate? Sodium What Are Side Effects of Sodium Bicarbonate? Common side effects of sodium bicarbonate include: • fever • infection at the site of injection • • fluid leakage from injection site, or • fluid overload ( Dosage for Sodium Bicarbonate Dosage of Sodium Bicarbonate depends on the condition being treated and the weight of the patient. What Drugs, Substances, or Supplements Interact with Sodium Bicarbonate? Sodium Bicarbonate may interact with other drugs. Tell your doctor all prescription and over-the-counter medications and supplements you use. Sodium Bicarbonate During Pregnancy and Breastfeeding During pregnancy, Sodium Bicarbonate should only be used if prescribed. Consult your doctor before breast-feeding. Additional Informationa Our Sodium Bicarbonate (sodium bicarbonate 5% injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Find Lowest Prices on DESCRIPTION 5% Composition Ionic Concentration (mEq/L) Sodium Bicarbonate (sodium bicarbonate 5% injection) , USP (NaHCO 3) (g/L) Osmolarity (mOsmol/L) (calc.) *pH Sodium Bicarbonate 5% Sodium Bicarbonate Injection, USP 50 1190 8 (7.0 to 8.5) 595 595 Approximately 0.007% edetate disodium added as a stabilizer. *pH adjusted with carbon dioxide. INDICATIONS Sodium Bicarbonate (sodium bicarbonate 5% injection) Injection may be indicated in the treatment of metabolic acidosis which can occur in seve...

DESCRIPTION Sodium Bicarbonate Injection, USP is a sterile, nonpyrogenic, hypertonic solution of sodium bicarbonate (NaHCO 3) in water for injection for administration by the intravenous route as an electrolyte replenisher and systemic alkalizer. The solution is offered in a concentration of 8.4% with a pH of 7.8 (7.0 to 8.5). Carbon dioxide or nitrogen may be used to adjust pH. See table in The solution contains no bacteriostat, antimicrobial agent or added buffer and is intended only for use as a single-dose injection. When smaller doses are required, the unused portion should be discarded with the entire unit. Sodium bicarbonate, 84 mg is equal to one milliequivalent each of Na + and HCO 3¯. Sodium Bicarbonate, USP is chemically designated NaHCO 3, a white crystalline powder soluble in water. Water for Injection, USP is chemically designated H 2O.

ADVERSE REACTIONS Overly aggressive therapy with Sodium Bicarbonate Injection, USP can result in metabolic alkalosis (associated with muscular twitchings, irritability and tetany) and hypernatremia. Inadvertent extravasation of intravenously administered hypertonic solutions of sodium bicarbonate have been reported to cause chemical cellulitis because of their alkalinity, with tissue necrosis, ulceration or sloughing at the site of infiltration. Prompt elevation of the part, warmth and local injection of lidocaine or hyaluronidase are recommended to reduce the likelihood of tissue sloughing from extravasated I.V. solutions. DESCRIPTION Sodium Bicarbonate Injection, USP is a sterile, nonpyrogenic, hypertonic solution of sodium bicarbonate (NaHCO 3 ) in water for injection for administration by the intravenous route as an electrolyte replenisher and systemic alkalizer. Solutions are offered in concentrations of 4.2%, 7.5% and 8.4%. See table in HOW SUPPLIED section for contents and characteristics. The solutions contain no bacteriostat, antimicrobial agent or added buffer and are intended only for use as a single-dose injection, the approximate pH of the solutions is 8. When smaller doses are required, the unused portion should be discarded. Sodium bicarbonate, 84 mg is equal to one milliequivalent each of Na + and HCO 3 - . Sodium Bicarbonate, USP is chemically designated NaHCO 3 , a white crystalline powder soluble in water. Water for Injection, USP is chemically designate...