Vasopressin

What is vasopressin? Vasopressin is used to treat Vasopressin is also used to treat or prevent certain conditions of the stomach after Vasopressin is used in emergency settings to raise blood pressure in adults who are in Vasopressin may also be used for purposes not listed in this medication guide. Related/similar drugs Before taking this medicine You should not be treated with vasopressin if you are allergic to vasopressin or chlorobutanol. Tell your doctor if you have ever had: • heart problems or • kidney disease; • • • In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine. Tell your doctor if you are pregnant. Vasopressin can cause premature labor contractions if you receive this medicine during the second or third trimester of pregnancy. You should not breastfeed within 1.5 hours after you are treated with vasopressin. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. How is vasopressin given? Vasopressin is injected into a muscle, or given as an infusion into a vein. A healthcare provider will give you this injection. To treat diabetes insipidus, vasopressin is sometimes given into the nose by nasal spray or medicine dropper, or insertion of a cotton pad that has been soaked in the medicine. Vasopressin can cause temporary side effects such as Drinking 1 or 2 glasses of water each time you receive an inj...

Indications and Usage for Vasopressin Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. Vasopressin Dosage and Administration Preparation of Solution Inspect parenteral drug products for particulate matter and discoloration prior to use, whenever solution and container permit. Vasopressin Injection Solution for Dilution, 20 units/mL Dilute Vasopressin injection in normal saline (0.9% sodium chloride) or 5% dextrose in water (D5W) prior to use for intravenous administration. Discard unused diluted solution after 18 hours at room temperature or 24 hours under refrigeration. Table 1 Preparation of diluted solutions Fluid restriction? Final concentration Mix Vasopressin injection Diluent No 0.1 units/mL 2.5 mL (50 units) 500 mL Yes 1 unit/mL 5 mL (100 units) 100 mL Administration In general, titrate to the lowest dose compatible with a clinically acceptable response. The recommended starting dose is: Post-cardiotomy shock: 0.03 units/minute Septic Shock: 0.01 units/minute Titrate up by 0.005 units/minute at 10- to 15-minute intervals until the target blood pressure is reached. There are limited data for doses above 0.1 units/minute for postcardiotomy shock and 0.07 units/minute for septic shock. Adverse reactions are expected to increase with higher doses. After target blood pressure has been maintained for 8 hours without the use of catecholamines, taper Vasopressin injecti...

What is vasopressin, and what is it used for? Vasopressin, also known as arginine vasopressin or antidiuretic hormone (ADH) is a natural substance primarily synthesized in the hypothalamus in the brain. Vasopressin regulates the body's fluid and Synthetically produced vasopressin is used to increase the blood pressure in adults who are in a state of severely • Contraction of smooth vessels around blood vessels that constricts the blood vessels and increases vascular resistance and arterial blood pressure • Increase in the reabsorption of water in the kidneys, reducing urine output and fluid loss, and increasing the blood volume • Contraction of smooth muscles in the gastrointestinal tract that promotes peristalsis, a series of contractions that move the gastrointestinal contents Vasopressin is typically administered with intravenous fluids and norepinephrine to restore normal blood pressure in adults in vasodilatory Off-label uses of vasopressin include: • • Abdominal distention that occurs after certain surgeries • To dispel shadows in abdominal x-ray (roentgenography) • Gastrointestinal hemorrhage • Part of Warnings • Do not use vasopressin in patients with known hypersensitivity to 8-L-arginine vasopressin, any of the components in vasopressin formulation, or chlorobutanol (multiple dose vial only, single dose vial does not contain chlorobutanol). • Reversible • Vasopressin may reduce heart rate and cardiac output, use with caution in patients with • Vasopressin may cau...